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Hulio (Adalimumab)

Prescription medicineOnly Available By Prescription

What if I find a lower price with another pharmacy?

We guarantee the lowest price on all of our prescription products. If you find your medications cheaper at any other recognized licensed mail order pharmacy, we will not only match their price, we will beat it by 25% of the difference. It is our 125% price match guarantee!

Example: If you find a product on Canada Drugs Direct for $50.00 and find the same product for $40.00 at another mail order pharmacy, we will provide you with a $12.50 discount, bringing your total to $37.50.

To get the discount please make sure to mention the price match to the customer service team when they call to collect payment for your order. Or call toll free at 1-888-904-8467 to place the order through the phone.

Terms & Conditions of Program

  • Guaranteed lowest price is only valid at the time of sale.
  • We will only match the current advertised price.
  • Products must be identical and in stock at the time of placing an order with a licensed mail order pharmacy. The must be a member of CIPA (Canadian International Pharmacy Association).
  • Products must be authentic in brand and size (same manufacturer, same country of manufacture, same pack size, same strength and same quantity).
  • Products must be new. We cannot match the price of any used, short expiry or expired product.
  • Price match can only be issued over the phone with our customer service team
What is a Generic Drug?

A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.

The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.

Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.


Hulio is an injection available by prescription only. It is used for the treatment of rheumatoid arthritis, juvenile idiopathic arthritis, psoriatic arthritis, ankylosing spondylitis, adult crohn's disease, ulcerative colitis, and plaque psoriasis.

Hulio is supplied as a 40 mg/0.8 mL single-dose prefilled pen for injection. It is also supplied as a prefilled plastic syringe for injection in the following strengths:

  • 40 mg/0.8 mL
  • 20 mg/0.4 mL

Fact Table




US DailyMed and EMA


64% (subcutaneous), 0% (by mouth)

Legal status


Chemical Name


Elimination half-life

10–20 days

Dosage (Strength)

40 mg/0.8 mL, 20 mg/0.4 mL


Consult doctor



Protein binding

Not Available

PubChem CID

Not Assigned




Not Assigned

ATC code






Routes of administration



The instructions that come with your Hulio prescription should be carefully read and followed. Use Hulio as prescribed by your doctor. Tell your doctor or pharmacist about any questions or concerns you may have.

Hulio dosage depends on the condition being treated. It also depends on the weight of the patient when being used to treat juvenile idiopathic arthritis. 

Your healthcare provider will teach you how and when to inject Hulio. Wait until your healthcare provider has shown you how to properly inject Hulio before you inject it yourself. 


The active ingredient in Hulio is adalimumab-fkjp, a tumor necrosis factor (TNF) blocker.

Methionine, monosodium glutamate, polysorbate 80, sorbitol, and Water for Injection, USP are the inactive ingredients. Hydrochloric acid is also added for pH balance. 


Hulio has no known contraindications.


Hulio has FDA Boxed Warnings regarding the increased risk of serious infections that can lead to hospitalization or death. In addition, there is a FDA Boxed Warning regarding the risk of lymphoma and other malignancies that can be fatal with the use of TNF blockers, including adalimumab products.

  • Before beginning treatment with Hulio, discuss the following with your doctor:
    • All the medications you use
    • Your allergies
    • Your health history and current health problems
    • Your pregnancy or breastfeeding status
  • Hulio has been associated with serious allergic reactions, including anaphylaxis. Seek emergency care immediately if you experience difficulty breathing, a rash, swelling of your lips, tongue, or throat, or other signs and symptoms of a severe reaction.
  • Hepatitis B virus in patients who are carriers of the virus may be reactivated with Hulio use.
  • Multiple sclerosis, optic neuritis, or Guillain-Barré syndrome may occur or worsen with Hulio use.
  • Hulio may cause abnormal blood cell counts. Seek medical care right away if you experience signs and symptoms of blood disorders or infection, including fever, bruising, bleeding, or pale appearance of the skin.
  • Hulio may cause heart failure. Seek medical care immediately if you experience difficulty breathing, swelling, or rapid weight gain.
  • Hulio may cause lupus-like syndrome.
  • Live vaccines are not recommended during treatment with Hulio.

Side Effects

Infections, injection site reactions, headache, and rash are some Hulio side effects. However, contact your doctor right away if you experience side effects that bother you or won't go away.


  1. Hulio (adalimumab-fkjp) injection, for subcutaneous use. Morgantown, WV: Mylan Pharmaceuticals Inc.; 2020.

IMPORTANT NOTE: The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.

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