Only Available By Prescription
Top brand choice
| Strength | Pack Size | Qty | |
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Strength
Dog Small Chewable under 25lbs (Blue Box)
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Strength
Dog Medium Chewable 26-50lbs (Green Box)
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Strength
Dog Large Chewable 51-100lbs (Brown Box)
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You'll have option to make 4 interest-free payments by credit card once your order is confirmed using
Top Generic choice
| Strength | Pack Size | Qty | |
|---|---|---|---|
|
Strength
Dog Small Chewable under 25lbs (Blue Box)
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Strength
Dog Small Chewable under 25lbs (Blue Box)
|
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|
Strength
Dog Medium Chewable 26-50lbs (Green Box)
|
|||
|
Strength
Dog Large Chewable 51-100lbs (Brown Box)
|
You'll have option to make 4 interest-free payments by credit card once your order is confirmed using
We guarantee the lowest price on all of our prescription products. If you find your medications cheaper at any other recognized licensed mail order pharmacy, we will not only match their price, we will beat it by 25% of the difference. It is our 125% price match guarantee!
Example: If you find a product on Canada Drugs Direct for $50.00 and find the same product for $40.00 at another mail order pharmacy, we will provide you with a $12.50 discount, bringing your total to $37.50.
To get the discount please make sure to mention the price match to the customer service team when they call to collect payment for your order. Or call toll free at 1-888-904-8467 to place the order through the phone.
Terms & Conditions of Program
A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.
The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.
Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.
Heartgard Plus offers a convenient and effective solution for preventing heartworm disease in dogs, providing peace of mind, and ensuring the health and well-being of their canine companions. However, it is important to administer the medication as a veterinarian directs and monitors for potential adverse reactions.
Heartgard Plus is a veterinary medication specifically formulated to prevent dog heartworm disease. It combines two active ingredients: ivermectin and pyrantel pamoate. Ivermectin is a broad-spectrum antiparasitic medication that works by interfering with the nervous system of heartworm larvae, preventing them from maturing into adults..
Pyrantel pamoate acts against roundworms and hookworms by paralyzing their muscles, allowing them to be expelled from the body through bowel movements. Heartgard Plus is a chewable tablet and is administered orally to dogs monthly.
| Fact Table | |
|---|---|
| Formula |
Ivermectin: C48H74O14 Pyrantel: C11H14N2S |
| License | FDA approved for veterinary use |
| Bioavailability |
Ivermectin: Approximately 35-40% Pyrantel: Poorly absorbed; primarily acts in the gastrointestinal tract |
| Legal status | Over-the-counter in many regions (veterinary) |
| Chemical Name |
Ivermectin: 22,23-Dihydroavermectin B1a and B1b mixture Pyrantel: 1,4,5,6-Tetrahydro-1-methyl-2-[2-(2-thienyl)vinyl]pyrimidine |
| Elimination half-life |
Ivermectin: Approximately 12-56 hours Pyrantel: Approximately 4-6 hours |
| Dosage (Strength) | Tablets and chewables: Dosage varies by animal weight, e.g., 68 mcg Ivermectin and 57 mg Pyrantel for dogs 51-100 lbs |
| Pregnancy | Consult a veterinarian; generally considered safe |
| Brands | Heartgard Plus |
| Protein binding |
Ivermectin: Approximately 93% Pyrantel: Not well-defined |
| PubChem CID |
Ivermectin: 6321424 Pyrantel: 5281031 |
| MedlinePlus | Not available |
| ChEBI |
Ivermectin: 7937 Pyrantel: 8690 |
| ATC code | Not available |
| DrugBank |
Ivermectin: DB00602 Pyrantel: DB11154 |
| KEGG |
Ivermectin: D01644 Pyrantel: D00413 |
| Routes of administration | Oral (chewable tablets) |
Heartgard Plus tablets are typically administered yearly to provide continuous protection against heartworm disease.
The dosage is based on the dog's weight, and it is important to follow the dosing schedule recommended by the veterinarian.
Administering Heartgard Plus regularly and on time is crucial for preventing heartworm infection and ensuring the dog's long-term health.
The active ingredients in Heartgard Plus are ivermectin and pyrantel.
The most common drug-drug interactions may include:
Heartgard Plus is generally safe for dogs of all breeds and sizes, including puppies as young as six weeks old.
Heartgard Plus should be used cautiously in dogs with a known hypersensitivity to the active ingredients. It is not recommended for cats or dogs with severe heartworm infections.
The most common side effects may include:
Heartgard Plus [package insert]. Duluth, GA: Boehringer Ingelheim; 2018.
Exceptional Customer Service
We pride ourselves on delivering excellent customer service with as much accessibility as possible.
If you have any questions at all, or would like to place an order, you are encouraged to contact us by toll-free
phone 1-888-904-8467 or email info@canadadrugsdirect.com.
Top Safety and Quality
Canada Drugs Direct employs dedicated, professional licensed pharmacists to ensure that each and every order is reviewed before it is dispensed for the safety and health of our customers. At CanadaDrugsDirect.com, your health is our top priority.
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