Halaven (Eribulin)

Prescription medicineOnly Available By Prescription
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What if I find a lower price with another pharmacy?

We guarantee the lowest price on all of our prescription products. If you find your medications cheaper at any other recognized licensed mail order pharmacy, we will not only match their price, we will beat it by 25% of the difference. It is our 125% price match guarantee!

Example: If you find a product on Canada Drugs Direct for $50.00 and find the same product for $40.00 at another mail order pharmacy, we will provide you with a $12.50 discount, bringing your total to $37.50.

To get the discount please make sure to mention the price match to the customer service team when they call to collect payment for your order. Or call toll free at 1-888-904-8467 to place the order through the phone.

Terms & Conditions of Program

  • Guaranteed lowest price is only valid at the time of sale.
  • We will only match the current advertised price.
  • Products must be identical and in stock at the time of placing an order with a licensed mail order pharmacy. They must be an online Canadian pharmacy with an address in Canada.
  • Products must be authentic in brand and size (same manufacturer, same country of manufacture, same pack size, same strength and same quantity).
  • Products must be new. We cannot match the price of any used, short expiry or expired product.
  • Price match can only be issued over the phone with our customer service team. Please note at this time we cannot offer price matching for the products Ozempic or Saxenda.
What is a Generic Drug?

A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.

The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.

Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.

Description

Halaven is a prescription medication used primarily to treat metastatic breast cancer and liposarcoma that has spread to other parts of the body. It is often prescribed for patients who have previously undergone other chemotherapy treatments.

Eribulin belongs to a class of drugs known as microtubule dynamics inhibitors. It stops the growth of cancer cells, ultimately leading to their death.

Fact Table
Formula C40H59NO11
License FDA approved
Bioavailability Not applicable (intravenous administration)
Legal status Prescription only
Chemical Name (2S,3R)-2-[(2R)-2-[(1R)-1-[(2R)-2-Methoxy-3-(methoxymethyl)-3,4,5,6-tetrahydropyran-2-yl]-3-methyl-2-oxo-2,3-dihydro-1H-pyrrolo[1,2-c][1,3]thiazol-4-yl]propyl]-3-[(2S,3R)-3-methyl-2-[(2R)-oxiran-2-yl]-4-oxopyrrolidin-3-yl]butyl methacrylate
Elimination half-life Approximately 40 hours
Dosage (Strength) 1 mg/2 mL solution for injection
Pregnancy Not recommended; consult a healthcare provider
Brands Halaven
Protein binding Approximately 49-65%
PubChem CID 10099248
MedlinePlus a611048
ChEBI 68820
ATC code L01XX41
DrugBank DB05886
KEGG D09732
Routes of administration Intravenous

Directions

Halaven is administered as an intravenous injection. The typical dosage is determined based on the body surface area and is usually given on days 1 and 8 of a 21-day cycle.

The dosage may be adjusted based on the response to treatment and if any side effects occur.

Halaven is given under the supervision of a healthcare professional, typically in a clinical setting.

Ingredients

The active ingredient in Halaven is eribulin.

Interactions

The most common interactions with Halaven may include:

  • Adagrasib
  • Amiodarone
  • Amisulpride
  • Anagrelide
  • Apomorphine
  • Aripiprazole
  • Aripiprazole Lauroxil
  • Arsenic Trioxide
  • Atazanavir
  • Azithromycin
  • Bepridil
  • Buprenorphine
  • Buserelin
  • Ceritinib
  • Chloroquine
  • Cisapride
  • Citalopram
  • Clarithromycin
  • Clofazimine
  • Clothiapine
  • Clozapine
  • Crizotinib
  • Dabrafenib
  • Dasatinib
  • Degarelix
  • Delamanid
  • Deslorelin
  • Deutetrabenazine
  • Dexmedetomidine
  • Domperidone
  • Donepezil
  • Dronedarone
  • Efavirenz
  • Encorafenib
  • Entrectinib
  • Escitalopram
  • Etrasimod
  • Fexinidazole
  • Fingolimod
  • Fluconazole
  • Fluoxetine
  • Formoterol
  • Foscarnet
  • Fostemsavir
  • Gepirone
  • Givinostat
  • Glasdegib
  • Gonadorelin
  • Goserelin
  • Histrelin
  • Hydroxychloroquine
  • Hydroxyzine
  • Iloperidone
  • Inotuzumab Ozogamicin
  • Itraconazole
  • Ivabradine
  • Ivosidenib
  • Ketoconazole
  • Lefamulin
  • Lenvatinib
  • Leuprolide
  • Levofloxacin
  • Levoketoconazole
  • Lofexidine
  • Macimorelin
  • Mesoridazine
  • Methadone
  • Metronidazole
  • Mirtazapine
  • Mobocertinib
  • Moxifloxacin
  • Nafarelin
  • Nilotinib
  • Olanzapine
  • Ondansetron
  • Osilodrostat
  • Osimertinib
  • Oxaliplatin
  • Ozanimod
  • Pacritinib
  • Panobinostat
  • Paroxetine
  • Pasireotide
  • Pazopanib
  • Phenobarbital
  • Pimavanserin
  • Pimozide
  • Piperaquine
  • Pitolisant
  • Ponesimod
  • Posaconazole
  • Primidone
  • Quetiapine
  • Quizartinib
  • Relugolix
  • Ribociclib
  • Saquinavir
  • Selpercatinib
  • Sertraline
  • Sevoflurane
  • Siponimod
  • Solifenacin
  • Sotalol
  • Sparfloxacin
  • Sulpiride
  • Sunitinib
  • Tacrolimus
  • Terfenadine
  • Thioridazine
  • Trazodone
  • Triclabendazole
  • Triptorelin
  • Vandetanib
  • Vardenafil
  • Vemurafenib
  • Venlafaxine
  • Vilanterol
  • Vinflunine
  • Voclosporin
  • Ziprasidone
  • Zuclopenthixol

Cautions

Halaven can cause serious side effects, including severe neutropenia, which increases the risk of infections.

Tell your doctor if you develop numbness, tingling, or pain in your extremities.

Tell your doctor if you have a history of heart or kidney problems before starting this drug.

Do not use this drug if you are pregnant or breastfeeding.

Side Effects

Common side effects of this drug include:

  • Alopecia
  • Anemia, All grades
  • Anemia, Grade 3 or greater
  • Constipation
  • Fatigue
  • Febrile neutropenia
  • Hypocalcemia
  • Hypokalemia
  • Nausea
  • Neutropenia, All grades
  • Neutropenia, Grade 3 or greater
  • Peripheral neuropathy
  • Prolonged QT interval
  • Sepsis
  • Neutropenic sepsis
  • Thrombocytopenia, Grade 3 or greater

References

Halaven [package insert]. Nutley, NJ: Eisai; September 2022.



IMPORTANT NOTE: The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.

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