Glyxambi (Empagliflozin/Linagliptin)

Prescription medicineOnly Available By Prescription

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What if I find a lower price with another pharmacy?

We guarantee the lowest price on all of our prescription products. If you find your medications cheaper at any other recognized licensed mail order pharmacy, we will not only match their price, we will beat it by 25% of the difference. It is our 125% price match guarantee!

Example: If you find a product on Canada Drugs Direct for $50.00 and find the same product for $40.00 at another mail order pharmacy, we will provide you with a $12.50 discount, bringing your total to $37.50.

To get the discount please make sure to mention the price match to the customer service team when they call to collect payment for your order. Or call toll free at 1-888-904-8467 to place the order through the phone.

Terms & Conditions of Program

  • Guaranteed lowest price is only valid at the time of sale.
  • We will only match the current advertised price.
  • Products must be identical and in stock at the time of placing an order with a licensed mail order pharmacy. They must be an online Canadian pharmacy with an address in Canada.
  • Products must be authentic in brand and size (same manufacturer, same country of manufacture, same pack size, same strength and same quantity).
  • Products must be new. We cannot match the price of any used, short expiry or expired product.
  • Price match can only be issued over the phone with our customer service team. Please note at this time we cannot offer price matching for the products Ozempic or Saxenda.
What is a Generic Drug?

A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.

The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.

Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.


Your healthcare provider may prescribe Glyxambi if you have type 2 diabetes mellitus. Type 2 diabetes is a condition where insulin levels are not high enough to manage blood sugar. This typically happens when a person's insulin resistance is too high, or the pancreatic cells are damaged.

Glyxambi cannot be used in people with type 1 diabetes mellitus.


Take Glyxambi exactly as directed by your doctor. Do not stop taking it without consulting your doctor first.

The standard dosage is one tablet by mouth once daily. It is available in the following formulations:

  • Empagliflozin/linagliptin 10/5 mg
  • Empagliflozin/linagliptin 25/5 mg


The active ingredients in Glyxambi are empagliflozin and linagliptin.

Empagliflozin works by causing a person to urinate extra glucose, and linagliptin helps regulate insulin and glucose levels after a person eats.


There are many potential drug-drug interactions with Glyxambi. Tell your doctor and pharmacist if you are taking any of the following:

  • Apalutamide
  • Carbamazepine
  • Enzalutamide
  • Fosphenytoin
  • Lumacaftor
  • Lumacaftor-ivacaftor
  • Mitotane
  • Phenobarbital
  • Phenytoin
  • Primidone
  • Rifampin (rifampicin)
  • Insulins
  • Carbamazepine 
  • Clotrimazole 
  • Dexamethasone 
  • Fosamprenavir 
  • Indinavir 
  • Morphine 
  • Nelfinavir 
  • Phenobarbital 
  • Phenothiazines 
  • Phenytoin 
  • Prazosin 
  • Retinoic acid
  • Rifampin 
  • Ritonavir 
  • Saquinavir 
  • St. John's Wort
  • Spironolactone 
  • Tipranavir 
  • Sulfonylureas


Tell your doctor if you have a history of kidney or liver problems before you start this medication.

Use with caution if you have a history of pancreatitis.

Ask your doctor for a full list of precautions that apply to you.

Side Effects

Possible Glyxambi may include the following:

  • Acute kidney injury
  • Bullous pemphigoid
  • Fournier's gangrene
  • Hypoglycemia
  • Increased hematocrit
  • Increased serum cholesterol
  • Nasopharyngitis
  • Rhabdomyolysis
  • Severe arthralgia
  • Skin rash
  • Upper respiratory tract infection
  • Urinary tract infection


  1. Glyxambi [package insert]. Indianapolis, IN: Eli Lilly and Company; 2015.

IMPORTANT NOTE: The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.

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