GlucaGen HypoKit (Glucagon)

Prescription medicineOnly Available By Prescription
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What if I find a lower price with another pharmacy?

We guarantee the lowest price on all of our prescription products. If you find your medications cheaper at any other recognized licensed mail order pharmacy, we will not only match their price, we will beat it by 25% of the difference. It is our 125% price match guarantee!

Example: If you find a product on Canada Drugs Direct for $50.00 and find the same product for $40.00 at another mail order pharmacy, we will provide you with a $12.50 discount, bringing your total to $37.50.

To get the discount please make sure to mention the price match to the customer service team when they call to collect payment for your order. Or call toll free at 1-888-904-8467 to place the order through the phone.

Terms & Conditions of Program

  • Guaranteed lowest price is only valid at the time of sale.
  • We will only match the current advertised price.
  • Products must be identical and in stock at the time of placing an order with a licensed mail order pharmacy. They must be an online Canadian pharmacy with an address in Canada.
  • Products must be authentic in brand and size (same manufacturer, same country of manufacture, same pack size, same strength and same quantity).
  • Products must be new. We cannot match the price of any used, short expiry or expired product.
  • Price match can only be issued over the phone with our customer service team. Please note at this time we cannot offer price matching for the products Ozempic or Saxenda.
What is a Generic Drug?

A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.

The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.

Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.

Description

Glucagon for Injection is used by adults and pediatric patients who have diabetes to treat severe low blood sugar. It may also be used to temporarily halt the movement of the gastrointestinal tract in adults during radiologic examinations.


Fact Table

Formula

C153H225N43O49S

License

US DailyMed, EU EMA

Bioavailability

significantly lower

Legal status

Rx-Only

Chemical Name

Glucagon

Elimination half-life

26 minutes

Dosage (Strength)

One Kit

Pregnancy

Consult doctor

Brands

GlucaGen HypoKit

Protein binding

Not Available

PubChem CID

16132283

MedlinePlus

a682480

ChEBI

5391

ATC code

H04AA01

DrugBank

DB00040

KEGG

D00116

Routes of administration

Nasal, intravenous (IV), intramuscular injection (IM), subcutaneous injection

Directions

The instructions that come with your Glucagon prescription should be followed. Go over the information with your family or caregivers. If you have any questions or concerns, you should talk to your doctor or pharmacist.

Glucagon Kits include a single-use vial of 1 mg Glucagon for Injection and a prefilled syringe of 1 mL of diluent for Glucagon.

Incorporate 1 mL of diluent into the glucagon vial. The vial should be swirled gently until the powder has dissolved and any particles can't be seen. Make sure that there are no particles or discoloration within the vial. The solution should be clear. If the solution appears cloudy or contains particulate matter, you should not use it. Next, the appropriate dose of Glucagon should be drawn up. Inject Glucagon subcutaneously, intramuscularly, or intravenously. Only healthcare professionals should perform intravenous injection. You should dispose of any unused medication after use. 

Recommended dosage for the treatment of severe low blood sugar in adults and pediatrics who weigh 20 kg or more: inject 1 mg (1 mL) subcutaneously or intramuscularly into the upper arm, thigh, or buttocks. Another dose may be administered while waiting for emergency care if there is no response to the glucagon after 15 minutes.

Recommended dosage for treatment in pediatrics who weigh under 20 kg: Inject 0.5 mg (0.5 mL) or dose equal to 20 mcg to 30 mcg per kg subcutaneously or intramuscularly into the upper arm, thigh, or buttocks. Another dose may be administered while waiting for emergency care if there is no response to the glucagon after 15 minutes.

Store Glucagon for Injection at temperatures between 68°F-77°F (20°C-25°C).

Ingredients

Each Glucagon Emergency Kit includes 1 mg Glucagon for Injection and a prefilled syringe containing 1 mL of diluent. 

Contraindications

If you have pheochromocytoma or insulinoma, you should not use glucagon. 

If you have any allergy to glucagon or any of its excipients, you should not use glucagon.

If you have glucagonoma, you should not use glucagon as a diagnostic aid. 

Cautions

  • Before beginning treatment with glucagon, tell your doctor:
    • If you have any allergies
    • About any medications you may take
      • Drug interactions can occur with use of other medications such as beta blockers, indomethacin, anticholinergic drugs, warfarin, and insulin. Ask your doctor if you do not know whether or not you take these medications.
    • If you have any health conditions
    • If you are pregnant or breastfeeding 
  • Patients with insulinoma may experience low blood sugar that may require treatment with oral or intravenous glucose.
  • Severe allergic reactions can occur with glucagon. Immediately seek emergency attention if you develop a rash, trouble breathing, low blood pressure, or swelling of your face, lips, tongue, or throat.
  • Patients who do not have enough glycogen present in their liver may not respond as well to glucagon. Patients who are in starvation, have adrenal insufficiency, or have chronic low blood sugar may not have enough glycogen. These patients may require treatment with glucose.
  • A skin rash called necrolytic migratory erythema may be caused by continuous administration of glucagon. Once treatment with glucagon is ceased, this condition goes away.
  • High blood sugar in patients with diabetes may be caused by using glucagon as a diagnostic aid.
  • High blood pressure and rapid heart rate in patients with heart disease may be caused by using glucagon as a diagnostic aid. 
  • Patients with glucagonoma may experience secondary low blood sugar with the use of glucagon. 

Side Effects

Immediately talk to your doctor if you develop side effects that persist or bother you. Some side effects associated with glucagon for Injection include: reactions at the injection site, nausea, vomiting, headache, dizziness, weakness, paleness of the skin, diarrhea, drowsiness, and low blood pressure.

Reference:

  1. Glucagon for Injection, for subcutaneous, intramuscular, or intravenous use. Indianapolis, IN: Lilly USA, LLC; 2021.


IMPORTANT NOTE: The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.

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