Fosamax Plus D (Alendronate / Colecalciferol)

Also Known as Fosavance

Prescription medicineOnly Available By Prescription

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Strength Pack Size Qty
70mg 2800IU
Pack Size
70mg 5600IU
Pack Size

You'll have option to make 4 interest-free payments by credit card once your order is confirmed using

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Strength Pack Size Qty
Pack Size
Pack Size

You'll have option to make 4 interest-free payments by credit card once your order is confirmed using

What if I find a lower price with another pharmacy?

We guarantee the lowest price on all of our prescription products. If you find your medications cheaper at any other recognized licensed mail order pharmacy, we will not only match their price, we will beat it by 25% of the difference. It is our 125% price match guarantee!

Example: If you find a product on Canada Drugs Direct for $50.00 and find the same product for $40.00 at another mail order pharmacy, we will provide you with a $12.50 discount, bringing your total to $37.50.

To get the discount please make sure to mention the price match to the customer service team when they call to collect payment for your order. Or call toll free at 1-888-904-8467 to place the order through the phone.

Terms & Conditions of Program

  • Guaranteed lowest price is only valid at the time of sale.
  • We will only match the current advertised price.
  • Products must be identical and in stock at the time of placing an order with a licensed mail order pharmacy. They must be an online Canadian pharmacy with an address in Canada.
  • Products must be authentic in brand and size (same manufacturer, same country of manufacture, same pack size, same strength and same quantity).
  • Products must be new. We cannot match the price of any used, short expiry or expired product.
  • Price match can only be issued over the phone with our customer service team. Please note at this time we cannot offer price matching for the products Ozempic or Saxenda.
What is a Generic Drug?

A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.

The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.

Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.


Fosamax Plus D (Alendronate and cholecalciferol) is a medication used to treat osteoporosis in postmenopausal women and to increase bone mass in men with osteoporosis.

Fosamax Plus D is a combination medication that includes both alendronate and vitamin D. Taken together, this combination helps to increase the formation of bone tissue and prevent bone loss to osteoporosis. 


Take Fosamax Plus D once weekly. It should be taken on the same day each week on an empty stomach at least 30 minutes before the first meal of the day.


FOSAMAX 70 mg/2800 I.U. contains 70 mg of alendronate sodium and 2800 international units of vitamin D.

Alendronate Sodium

Alendronate sodium belongs to the drug class bisphosphonates. It localizes to sites of bone formation and is taken up by osteoclasts, which are responsible for bone resorption. After it is taken up by osteoclasts, it adheres to their cell membrane and acts as a cellular scaffold for bone formation. Alendronate is permanently incorporated into bone tissue and the administration must continue to prevent bone loss and to cause the formation of new bone mass.

Vitamin D

Vitamin is a naturally occuring hormone that is formed in skin cells upon exposure to ultraviolet (UV) light. Vitamin D may also be absorbed orally in the diet. 

Vitamin D is responsible for regulating calcium and phosphate levels in the body. It increases the absorption of the minerals calcium and phosphate and regulates how much is lost via renal excretion.


Osteonecrosis (ONJ) of the jaw has been reported in patients taking bisphosphonates. Risk factors include invasive dental procedures, cancer, drug interactions, poor oral hygiene, and certain comorbid disorders. The risk of ONJ may increase with the duration of exposure.

Fosamax Plus D is not recommended for patients with impaired renal function.

This is not a complete list of warnings and precautions; speak with your doctor about your known medical history before starting Fosamax Plus D.

Side Effects

Common adverse effects of Fosamax Plus D include:

  • Abdominal pain
  • Acid regurgitation
  • Constipation
  • Diarrhea
  • Dyspepsia
  • Musculoskeletal pain
  • Nausea

If you experience any of these side effects, speak with your prescriber.

Those looking for where to buy Fosamax Plus D can purchase the medication from Canada Drugs Direct. Buy Fosamax Plus D with a valid prescription from your doctor. 


  1. Fosamax Plus D [Package Insert]. Whitehouse Station, NJ: Merck, 2007.

IMPORTANT NOTE: The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.

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