Forteo (Teriparatide)

Prescription medicineOnly Available By Prescription

What if I find a lower price with another pharmacy?

We guarantee the lowest price on all of our prescription products. If you find your medications cheaper at any other recognized licensed mail order pharmacy, we will not only match their price, we will beat it by 25% of the difference. It is our 125% price match guarantee!

Example: If you find a product on Canada Drugs Direct for $50.00 and find the same product for $40.00 at another mail order pharmacy, we will provide you with a $12.50 discount, bringing your total to $37.50.

To get the discount please make sure to mention the price match to the customer service team when they call to collect payment for your order. Or call toll free at 1-888-904-8467 to place the order through the phone.

Terms & Conditions of Program

  • Guaranteed lowest price is only valid at the time of sale.
  • We will only match the current advertised price.
  • Products must be identical and in stock at the time of placing an order with a licensed mail order pharmacy. They must be an online Canadian pharmacy with an address in Canada.
  • Products must be authentic in brand and size (same manufacturer, same country of manufacture, same pack size, same strength and same quantity).
  • Products must be new. We cannot match the price of any used, short expiry or expired product.
  • Price match can only be issued over the phone with our customer service team. Please note at this time we cannot offer price matching for the products Ozempic or Saxenda.
What is a Generic Drug?

A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.

The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.

Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.

Description

Forteo (teriparatide injection) is a recombinant form of human parathyroid hormone (PTH 1–34) indicated for the treatment of osteoporosis in adults at high risk for fracture. It stimulates new bone formation by activating osteoblasts more than osteoclasts, leading to increased bone mineral density (BMD) and strength. Forteo is approved for use in postmenopausal women with osteoporosis, men with primary or hypogonadal osteoporosis, and both sexes with glucocorticoid-induced osteoporosis who are at high fracture risk or have failed other therapies.

Fact Table

Formula

C181H291N55O51S2

License

US FDA (2002); EMA

Bioavailability

~95% (subcutaneous)

Legal status

Prescription only

Chemical Name

Teriparatide (recombinant human parathyroid hormone 1-34)

Elimination half-life

~1 hour (subcutaneous injection)

Dosage (Strength)

20 mcg/day (pen delivers 28 doses; 600 mcg/2.4 mL)

Pregnancy

Category C – risk cannot be ruled out

Brands

Forteo, Terifrac (India), Bonsity (biosimilar)

Protein binding

Not protein-bound; rapidly cleared

PubChem CID

16132397

MedlinePlus

a605030

ChEBI

CHEBI:75039

ATC code

H05AA02

DrugBank

DB06285

KEGG

D04572

Routes of administration

Subcutaneous injection (abdomen or thigh)

Directions

Forteo is administered subcutaneously once daily at a dose of 20 mcg, typically in the thigh or abdomen.

  • Supplied in a pre-filled multi-dose pen delivering 28 daily doses.
  • Store refrigerated (2°C to 8°C / 36°F to 46°F); do not freeze.
  • Discard the pen 28 days after first use, even if medication remains.

Patients should be instructed on proper self-injection technique and use of the pen. Calcium and vitamin D supplementation should be provided as needed.

Ingredients

Each 80 mcL dose contains:

  • Teriparatide 20 mcg

Inactive ingredients:

  • Acetic acid, sodium acetate, mannitol, metacresol (preservative), and water for injection

Contraindications

Forteo is contraindicated in patients with:

  • Hypercalcemia
  • Bone metastases or history of skeletal malignancies
  • Paget’s disease of bone
  • Unexplained elevations of alkaline phosphatase
  • Pediatric patients or those with open epiphyses
  • Prior external beam or implant radiation therapy involving the skeleton
  • Hypersensitivity to teriparatide or formulation components

Cautions

Boxed Warning: In animal studies, teriparatide caused osteosarcoma. While the relevance to humans is unknown, use is limited to a lifetime maximum of 2 years.

Use caution in patients with urolithiasis, as teriparatide may raise serum calcium levels. Monitor serum calcium, urinary calcium excretion, and orthostatic blood pressure, particularly in the first weeks of therapy. Avoid use in patients at increased baseline risk of osteosarcoma. Not recommended in children or young adults with open epiphyses.

Side Effects

Common and potential side effects include:

  • Nausea
  • Leg cramps
  • Dizziness or orthostatic hypotension
  • Arthralgia
  • Hypercalcemia (mild and transient)
  • Injection site reactions
  • Rare: osteosarcoma (boxed warning), hyperuricemia, antibody formation

IMPORTANT NOTE: The information provided above is for general awareness and educational purposes only. It is not intended to diagnose, treat, or replace professional medical or veterinary advice. Always consult your physician, pharmacist, or veterinarian regarding the safety, suitability, and proper use of any medication for yourself or your pet.

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