Floxin (Ofloxacin)

Description

Floxin, also known by its generic name Ofloxacin, is a fluoroquinolone antibiotic that targets a wide range of bacterial infections. This medication blocks the replication of bacterial DNA, an essential process for bacterial growth and survival. Floxin is a broad-spectrum antibiotic suitable for treating illnesses such as bronchitis, pneumonia, skin infections, and urinary tract infections.

Directions

Floxin is typically available in different forms, such as oral tablets and ear drops. The dosage and dosage form will depend on the infection being treated and the severity of symptoms. Oral administration of Ofloxacin typically requires swallowing the tablets whole, usually once or twice a day. It's crucial to complete the full course as prescribed, even if symptoms improve sooner, to prevent the development of resistant bacteria. Follow the specific instructions provided by your healthcare provider.

Ingredients

Ofloxacin is the main active ingredient in Floxin. Inactive ingredients may include hydroxypropyl cellulose, hypromellose, and magnesium stearate.

Contraindications

Avoid taking or using this medication if you have a history of hypersensitivity or allergies to Ofloxacin or any other quinolone antibiotics.

Cautions

• Consult a healthcare provider about the following before starting Floxin:
• Any allergies you may have
• If you are pregnant or breastfeeding
• Any other medical conditions you have
• Any medications you are currently taking
• Floxin can lead to tendon problems, such as tendinitis or even tears, across all ages. This is especially true for the Achilles tendon. Older adults, those using steroids, and people with kidney, heart, or lung transplants are at higher risk.
• Before and during your Floxin treatment, you'll need tests to check how your liver is doing, as Floxin can cause liver issues.
• Pay attention to any new or worsening breathing problems. Floxin might cause lung issues, necessitating a change in your medication plan.
• If you have high blood pressure, it needs to be controlled before starting Floxin. Your doctor will monitor your blood pressure closely after starting the medication.
• Because Floxin can affect your heart's rhythm, it's important to have this monitored, especially if you're already at risk for heart conditions.
• Floxin can make your skin more sensitive to sunlight, so it's advised to limit sun exposure and avoid tanning beds while on this medication.
• For those with conditions like myasthenia gravis that cause muscle weakness, Floxin may exacerbate these symptoms. It's generally recommended to avoid Floxin if you have such conditions.
• Floxin can cause issues like seizures, agitation, or confusion. It should be used with caution in individuals prone to seizures.
• Be aware of possible serious allergic reactions to Floxin, which can occur even after the first dose. Symptoms like swelling, difficulty breathing, or hives mean you should stop the medication and seek immediate medical attention.
• The safety and effectiveness of Floxin in children, pregnant women, and nursing mothers have not been established. Additionally, it can cause harm to an unborn baby, and there's a potential for serious side effects in nursing infants.

Side Effects

Floxin commonly causes nausea, insomnia, headaches, dizziness, diarrhea, vomiting, rash, pruritus, and symptoms like genital irritation and taste disturbances. Most of these effects are mild to moderate and occur at the beginning of the treatment.

Serious Floxin antibiotic side effects may include an increased risk of tendonitis and tendon rupture, especially in individuals over 60, those on corticosteroid therapy, and patients with certain transplants. It can worsen muscle weakness in people with myasthenia gravis. Central nervous system effects such as seizures, confusion, and hallucinations have been reported. Nerve pain in the arms and legs, serious hypersensitivity reactions, and Clostridium difficile-associated diarrhea are also potential serious side effects. Immediate discontinuation of Floxin and professional medical help are advised if serious symptoms develop.

References:

1. Floxin (Ofloxacin) Product Monograph. Raritan, NJ: Ortho-McNeil-JanssenPharmaceuticals; 2011.
2. Floxin (Ofloxacin) Product Monograph. Montvale, NJ: Daiichi Pharmaceutical Corporation; 2005.

About Dr. Gerardo Sison (Page Author)

An honors graduate of the University of Florida, Dr. Sison started his pharmacy career in a community setting, extending his services to hospitals and clinics over time. He has also worked in medication therapy management, advising patients on proper medication use for their chronic health conditions. Read More....