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Florinef (Fludrocortisone)

Prescription medicineOnly Available By Prescription

Top brand choice

Strength Pack Size Qty
Pack Size

You'll have option to make 4 interest-free payments by credit card once your order is confirmed using

What if I find a lower price with another pharmacy?

We guarantee the lowest price on all of our prescription products. If you find your medications cheaper at any other recognized licensed mail order pharmacy, we will not only match their price, we will beat it by 25% of the difference. It is our 125% price match guarantee!

Example: If you find a product on Canada Drugs Direct for $50.00 and find the same product for $40.00 at another mail order pharmacy, we will provide you with a $12.50 discount, bringing your total to $37.50.

To get the discount please make sure to mention the price match to the customer service team when they call to collect payment for your order. Or call toll free at 1-888-904-8467 to place the order through the phone.

Terms & Conditions of Program

  • Guaranteed lowest price is only valid at the time of sale.
  • We will only match the current advertised price.
  • Products must be identical and in stock at the time of placing an order with a licensed mail order pharmacy. They must be an online Canadian pharmacy with an address in Canada.
  • Products must be authentic in brand and size (same manufacturer, same country of manufacture, same pack size, same strength and same quantity).
  • Products must be new. We cannot match the price of any used, short expiry or expired product.
  • Price match can only be issued over the phone with our customer service team. Please note at this time we cannot offer price matching for the products Ozempic or Saxenda.
What is a Generic Drug?

A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.

The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.

Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.


Florinef is a prescription adrenal gland disease medication that addresses low glucocorticoid levels and re-establishes salt and water balances as well as normalizing blood pressure. Fludrocortisone can be a treatment for Addison's disease too as well as for adrenocortical insufficiency, and this medication also helps with better breaking down of carbohydrates in your diet. Florinef uses also include for hypothyroidism as this medication works very well to bring up blood pressure levels when needed.

You can buy Florinef with a doctor's prescription, and your best price on it will be when you order medication online from Canada Drugs Direct.

Fact Table







Legal status


Chemical Name


Elimination half-life

3.5 hours

Dosage (Strength)






Protein binding


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ATC code






Routes of administration

By mouth


The standard Florinef dosage is to take the medication once daily or as indicated in your prescription. It is also best to take the medication at around the same time every day.

Do not exceed dosage regulations as indicated in your prescription.


The active ingredient in Florinef is Fludrocortisone.


Tell your doctor if you have any history of fungal blood infections, bleeding problems, blood clots, brittle bones (osteoporosis), diabetes, eye problems, heart problems, high blood pressure, infections, kidney or liver disease, mental or mood disorders, low blood minerals, stomach or intestinal problems, seizure, or thyroid problems before beginning on Florinef.

This medication may cause the body to retain salt (sodium) and get rid of excessive levels of other salts like calcium and potassium. Also tell your doctor of any physiological conditions or dietary preferences that might be relevant given this information and using Florinef.

Florinef may also mask signs of infection and put you at greater risk of infections while you are being treated with the medication.

It is best to not be immunized or vaccinated while using Florinef, and you should also be mindful of avoiding exposing to chicken pox or measles while using it.

Florinef may cause diabetics to have difficulty controlling their blood sugar levels. Older people may be more susceptible to Florinef side effects, especially water retention.


There is the possibility of drug interaction risks between Florinef and other Rx medications, including aldesleukin, digoxin, antiplatelet drugs like clopidogrel, blood thinners like dabigatran and warfarin, NSAIDs like aspirin, celecoxib and ibuprofen, hormonal birth control pills, estrogens, immunosuppressants like cyclosporine, mifepristone, rifampin/rifabutin, and certain anti-seizure medicines like phenytoin. Tell your doctor of all medications you are currently taking before getting a prescription and proceeding to buy Florinef.

Side Effects

Florinef side effects are uncommon, but some users may experience skin appearance changes, enhanced bruising or bleeding, dizziness, slow wound healing, signs of infection, bone and joint pain, muscle pain, puffy face or swelling of hands or feet, exhaustion, increased thirst and urination, unusual weight gain, or muscle weakness. If Florinef side effects are experienced, then you should discontinue use and speak with your doctor again regarding adrenal gland dysfunction treatment options.

IMPORTANT NOTE: The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.


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