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Femring (Estradiol acetate)

Prescription medicineOnly Available By Prescription
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What if I find a lower price with another pharmacy?

We guarantee the lowest price on all of our prescription products. If you find your medications cheaper at any other recognized licensed mail order pharmacy, we will not only match their price, we will beat it by 25% of the difference. It is our 125% price match guarantee!

Example: If you find a product on Canada Drugs Direct for $50.00 and find the same product for $40.00 at another mail order pharmacy, we will provide you with a $12.50 discount, bringing your total to $37.50.

To get the discount please make sure to mention the price match to the customer service team when they call to collect payment for your order. Or call toll free at 1-888-904-8467 to place the order through the phone.

Terms & Conditions of Program

  • Guaranteed lowest price is only valid at the time of sale.
  • We will only match the current advertised price.
  • Products must be identical and in stock at the time of placing an order with a licensed mail order pharmacy. The must be a member of CIPA (Canadian International Pharmacy Association).
  • Products must be authentic in brand and size (same manufacturer, same country of manufacture, same pack size, same strength and same quantity).
  • Products must be new. We cannot match the price of any used, short expiry or expired product.
  • Price match can only be issued over the phone with our customer service team
What is a Generic Drug?

A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.

The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.

Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.

Description

Femring is a vaginal ring that contains a female hormone called estradiol acetate. Femring is used to treat hot flashes, vaginal irritation, and vaginal dryness in menopausal women.

Directions

You or your doctor may insert Femring. Hands should be washed before and after inserting the ring. Follow the instructions that come with your prescription. Call your doctor if you need help with inserting the ring.

Femring should remain in place for 3 months. After 3 months you should remove your old ring and insert a new ring. 

Ingredients

The active ingredient in Femring is the female hormone, estradiol acetate.

Contraindications

You should not use Femring if you have any of the following conditions:

  • Undiagnosed abnormal genital bleeding
  • Known, suspect, or have a history of breast cancer
  • Have or suspect estrogen-dependent neoplasia
  • Known or a history of deep vein thrombosis or a pulmonary embolism
  • Known or have had a stroke or heart attack within the past year
  • Liver problems or liver disease
  • Allergic to estradiol acetate or any of the other ingredients in Femring
  • Pregnant or suspect you are pregnant. Tell your doctor if you plan to become pregnant

Cautions

WARNING: ENDOMETRIAL CANCER, CARDIOVASCULAR DISORDERS AND PROBABLE DEMENTIA FOR ESTROGEN-ALONE THERAPY

ENDOMETRIAL CANCER

There is an increased risk of endometrial cancer in a woman with a uterus who uses unopposed estrogens. Adding a progestin to estrogen therapy has been shown to reduce the risk of endometrial hyperplasia, which may be a precursor to endometrial cancer. Adequate diagnostic measures, including directed or random endometrial sampling when indicated, should be undertaken to rule out malignancy in postmenopausal women with undiagnosed persistent or recurring abnormal genital bleeding. 

CARDIOVASCULAR DISORDERS AND PROBABLE DEMENTIA

Estrogen-alone therapy should not be used for the prevention of cardiovascular disease or dementia. 

The Women's Health Initiative (WHI) estrogen-alone substudy reported increased risks of stroke and deep vein thrombosis (DVT) in postmenopausal women (50 to 79 years of age) during 7.1 years of treatment with daily oral conjugated estrogens (CE) [0.625 mg], relative to placebo. 

The Women's Health Initiative Memory Study (WHIMS) estrogen-alone ancillary study of the WHI reported increased risk of developing probable dementia in postmenopausal women 65 years of age or older during 5.2 years of treatment with daily CE (0.625 mg)-alone, relative to placebo. It is unknown whether this finding applies to younger postmenopausal women.

In the absence of comparable data, these risks should be assumed to be similar for other doses of CE and other dosage forms of estrogens.

Estrogens with or without progestins should be prescribed at the lowest effective doses and for the shortest duration consistent with treatment goals and risks for the individual woman.

WARNING: CARDIOVASCULAR DISORDERS, BREAST CANCER AND PROBABLE DEMENTIA FOR ESTROGEN PLUS PROGESTIN THERAPY

Estrogens plus progestin therapy should not be used for the prevention of cardiovascular disease or dementia. 

The WHI estrogen plus progestin substudy reported increased risks of DVT, pulmonary embolism, stroke, and myocardial infarction in postmenopausal women (50 to 79 years of age) during 5.6 years of treatment with daily oral CE (0.625 mg) combined with medroxyprogesterone acetate (MPA) [2.5 mg], relative to placebo. 

The WHI estrogen plus progestin substudy also demonstrated an increased risk of invasive breast cancer. 

The WHIMS estrogen plus progestin ancillary study of the WHI reported an increased risk of developing probable dementia in postmenopausal women 65 years of age or older during 4 years of treatment with daily CE (0.625 mg) combined with MPA (2.5 mg), relative to placebo. It is unknown whether this finding applies to younger postmenopausal women. 

In the absence of comparable data, these risks should be assumed to be similar for other doses of CE and MPA therapy and other combinations and dosage forms of estrogens and progestins.

Estrogens with or without progestins should be prescribed at the lowest effective doses and for the shortest duration consistent with treatment goals and risks for the individual woman.

  • Tell your doctor about any allergies you have.
  • Tell your doctor about all the prescription and over-the-counter medications you take, including vitamins and herbal supplements.
  • Femring may increase your risk for gallbladder disease.
  • Femring may cause elevations in your blood calcium levels.
  • Femring may cause vision problems.
  • Tell your doctor if you have high blood pressure.
  • Tell your doctor if you have high cholesterol.
  • Tell your doctor if you have thyroid problems.
  • Tell your doctor if you are going to have surgery.
  • Tell your doctor if you are pregnant or plan to become pregnant.
  • Tell your doctor if you are breastfeeding or plan to breastfeed.

Side Effects

Femring can cause side effects such as breast pain, headache, spotting or irregular vaginal bleeding, stomach cramps, bloating, nausea, vomiting, and hair loss. These are not all the possible side effects. Contact your doctor right away if you experience side effects that are troublesome or persistent.

Seek emergency care immediately if you experience:

  • Signs and symptoms of a blood clot such as chest pain, vision problems, breathing problems, cough, pain, swelling, redness, or warmth in the leg
  • Signs and symptoms of a stroke such as weakness on one side of your body, trouble breathing, headaches, slurred speech, vision problems
  • Signs and symptoms of a heart attack such as chest pain, cold sweats, pain in the left arm, trouble breathing

With a valid prescription, you can purchase Femring online at a competitive price at Canada Drugs Direct.

References:

  1. Femring Prescribing Information. Rockaway, NJ: Warner Chilcott Inc.; 2005.
  2. Estradiol acetate vaginal ring (Femring). Cleveland Clinic. Accessed January 30, 2022. 


IMPORTANT NOTE: The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.

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