Eucrisa (Crisaborole)

Prescription medicineOnly Available By Prescription

Top brand choice

Strength Pack Size Qty
Ointment 20mg/g (2%)
Pack Size

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What if I find a lower price with another pharmacy?

We guarantee the lowest price on all of our prescription products. If you find your medications cheaper at any other recognized licensed mail order pharmacy, we will not only match their price, we will beat it by 25% of the difference. It is our 125% price match guarantee!

Example: If you find a product on Canada Drugs Direct for $50.00 and find the same product for $40.00 at another mail order pharmacy, we will provide you with a $12.50 discount, bringing your total to $37.50.

To get the discount please make sure to mention the price match to the customer service team when they call to collect payment for your order. Or call toll free at 1-888-904-8467 to place the order through the phone.

Terms & Conditions of Program

  • Guaranteed lowest price is only valid at the time of sale.
  • We will only match the current advertised price.
  • Products must be identical and in stock at the time of placing an order with a licensed mail order pharmacy. They must be an online Canadian pharmacy with an address in Canada.
  • Products must be authentic in brand and size (same manufacturer, same country of manufacture, same pack size, same strength and same quantity).
  • Products must be new. We cannot match the price of any used, short expiry or expired product.
  • Price match can only be issued over the phone with our customer service team. Please note at this time we cannot offer price matching for the products Ozempic or Saxenda.
What is a Generic Drug?

A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.

The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.

Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.


Eucrisa, or Crisaborole, is a topical prescription medication primarily used to treat mild to moderate atopic dermatitis, commonly known as eczema, in pediatric and adult patients.

It belongs to the class of non-steroidal phosphodiesterase 4 (PDE-4) inhibitors. The active ingredient works by increasing cyclic adenosine monophosphate (cAMP) levels and reducing inflammation involved in the immune response, relieving symptoms associated with eczema.


Apply a thin layer to the affected area(s) twice daily.

Eucrisa is for external use only. Do not use in the eyes, ears, nose, vagina, or other mucus membranes.

The hands should be washed thoroughly after each application, and contact with the eyes, mouth, and other mucous membranes should be avoided.

Do not apply Eucrisa to open wounds or sores.


The active ingredient in Eucrisa is crisaborole.

Inactive ingredients include the following:

  • Butylated hydroxytoluene
  • Diglycerides
  • Edetate calcium disodium
  • Monoglycerides
  • Paraffin
  • Propylene glycol
  • White petrolatum


There are no significant drug-drug interactions between Eucrisa and other medications. However, tell your doctor and pharmacist about all other drugs you are taking before starting Eucrisa.


Patients using Eucrisa should exercise caution and inform their healthcare provider about any existing medical conditions, especially those related to skin infections or sensitivities. Following the prescribed dosage and application instructions is essential to prevent any adverse effects.

Do not use this drug if you have any allergies to Eucrisa or inactive ingredients. Hypersensitivity reactions may occur at the application site and can include redness, swelling, itching, hives, and trouble breathing.

Tell your doctor if you have any history of kidney problems because Eucrisa is mainly metabolized by the kidneys.

Side Effects

Common adverse reactions to this drug may include:

  • Application site pain
  • Hypersensitivity reaction


Eucrisa [package insert]. New York, NY: Pfizer; March 2020.

IMPORTANT NOTE: The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.

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