Erleada (Apalutamide)

Prescription medicineOnly Available By Prescription
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Strength Pack Size Qty
Strength
60mg
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Strength
240mg
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What if I find a lower price with another pharmacy?

We guarantee the lowest price on all of our prescription products. If you find your medications cheaper at any other recognized licensed mail order pharmacy, we will not only match their price, we will beat it by 25% of the difference. It is our 125% price match guarantee!

Example: If you find a product on Canada Drugs Direct for $50.00 and find the same product for $40.00 at another mail order pharmacy, we will provide you with a $12.50 discount, bringing your total to $37.50.

To get the discount please make sure to mention the price match to the customer service team when they call to collect payment for your order. Or call toll free at 1-888-904-8467 to place the order through the phone.

Terms & Conditions of Program

  • Guaranteed lowest price is only valid at the time of sale.
  • We will only match the current advertised price.
  • Products must be identical and in stock at the time of placing an order with a licensed mail order pharmacy. They must be an online Canadian pharmacy with an address in Canada.
  • Products must be authentic in brand and size (same manufacturer, same country of manufacture, same pack size, same strength and same quantity).
  • Products must be new. We cannot match the price of any used, short expiry or expired product.
  • Price match can only be issued over the phone with our customer service team. Please note at this time we cannot offer price matching for the products Ozempic or Saxenda.
What is a Generic Drug?

A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.

The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.

Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.

Description

Erleada (Apalutamide) is an androgen receptor inhibitor prescribed for the management of specific types of prostate cancer. It works by obstructing the action of androgens, which are male hormones that can promote tumor growth in the prostate. Classified as a nonsteroidal antiandrogen, it can help treat metastatic castration-sensitive prostate cancer and non-metastatic castration-resistant prostate cancer. Doctors prescribe Erleada to control the progression of prostate cancer that is either still responsive to treatments lowering testosterone levels or that has become resistant to such treatments.

Directions

Erleada is taken orally, and patients typically swallow the tablets whole without crushing, chewing, or breaking them. The standard dosage for individuals is 240 mg once daily. Patients can take Erleada with or without food. It should be taken alongside a gonadotropin-releasing hormone (GnRH) analog or after a bilateral orchiectomy (removal of the testicles).

Ingredients

Apalutamide is the active ingredient in Erleada. The inactive ingredients may include lactose monohydrate, croscarmellose sodium, magnesium stearate, and colloidal silicon dioxide, forming the tablet's core.

Contraindications

No contraindications are listed on the FDA label. However, avoid taking or using this medication if you have a known hypersensitivity to Apalutamide or any component of the formulation.

Cautions

  • Before starting Erleada, inform your doctor about:
    • Any medical conditions you have
    • All medications being taken
    • Whether you partner is pregnant or breastfeeding
  • Patients taking Erleada may face risks related to heart and brain blood vessels, such as ischemic heart disease and cerebrovascular disorders.
  • There is an increased risk of bone fractures in patients using Erleada. Assessing bone health and fracture risk is key, and treatment following established guidelines for bone protection may be necessary.
  • Falls are more common in patients taking Erleada, particularly in older adults. Assessing and managing factors that increase fall risk is an important part of treatment with Erleada.
  • Seizures have been reported in a small percentage of patients on Erleada. If a seizure occurs, the medication should be stopped permanently.
  • In rare cases, severe skin reactions, including Stevens-Johnson syndrome and toxic epidermal necrolysis, have been reported among those taking Erleada. If symptoms of these severe skin reactions appear, Erleada should be paused and, if confirmed, discontinued permanently.
  • Erleada can be harmful to an unborn baby. Men with partners of childbearing potential should use effective contraception during treatment to prevent potential harm to the fetus.

Side Effects

Common Erleada side effects include feeling extremely tired, experiencing weight loss, joint pain, high blood pressure, rashes, hot flashes, diarrhea, decreased appetite, fractures, and falls. Patients are advised to notify their healthcare provider if they develop a rash or any other listed symptoms.

Serious side effects of Erleada can include heart disease, stroke, or mini-strokes. Patients should be vigilant for signs like chest pain, shortness of breath, speech or vision difficulties, numbness or weakness, dizziness, or balance issues. The medication also increases the risks of falls, fractures, and seizures. In addition, severe skin reactions, which can be life-threatening, involve symptoms like escalating rashes, fever, swollen lymph nodes, blisters, or peeling skin. Immediate medical attention is vital if these serious symptoms occur.

References:

  1. Erleada (Apalutamide) Product Monograph. Horsham, PA: Janssen Pharmaceuticals; 2023.
  2. Erleada (Apalutamide) Drug Label Information. Horsham, PA: Janssen Pharmaceuticals; 2023.



IMPORTANT NOTE: The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.

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