Emend (Aprepitant)

Prescription medicineOnly Available By Prescription

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What if I find a lower price with another pharmacy?

We guarantee the lowest price on all of our prescription products. If you find your medications cheaper at any other recognized licensed mail order pharmacy, we will not only match their price, we will beat it by 25% of the difference. It is our 125% price match guarantee!

Example: If you find a product on Canada Drugs Direct for $50.00 and find the same product for $40.00 at another mail order pharmacy, we will provide you with a $12.50 discount, bringing your total to $37.50.

To get the discount please make sure to mention the price match to the customer service team when they call to collect payment for your order. Or call toll free at 1-888-904-8467 to place the order through the phone.

Terms & Conditions of Program

  • Guaranteed lowest price is only valid at the time of sale.
  • We will only match the current advertised price.
  • Products must be identical and in stock at the time of placing an order with a licensed mail order pharmacy. They must be an online Canadian pharmacy with an address in Canada.
  • Products must be authentic in brand and size (same manufacturer, same country of manufacture, same pack size, same strength and same quantity).
  • Products must be new. We cannot match the price of any used, short expiry or expired product.
  • Price match can only be issued over the phone with our customer service team. Please note at this time we cannot offer price matching for the products Ozempic or Saxenda.
What is a Generic Drug?

A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.

The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.

Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.


EMEND (Aprepitant) is prescribed to treat chemotherapy-induced nausea and vomiting (CINV). EMEND is typically prescribed by oncologists and administered during chemotherapy regimens.

EMEND is used in combination with other antiemetics in patients taking moderately or highly emetic chemotherapy regimens.

EMEND works by blocking substance P/neurokinin 1 (NK1) receptors. NK1 receptors generate feelings of nausea and vomiting. EMEND blocks these receptors to prevent CINV.


EMEND should be taken exactly as directed by the oncologist. 

EMEND can be taken with or without food. Do not crush or open the capsules; swallow them whole.

EMEND is usually taken on the following schedule:

  • Day 1: 125 mg by mouth 1 hour before chemotherapy
  • Day 2: 80 mg by mouth 1 hour before chemotherapy
  • Day 3: 80 mg by mouth 1 hour before chemotherapy


The active ingredient in EMEND is aprepitant.


There are many possible drug interactions when taking EMEND. Some of the examples may include:

  • Benzodiazepines
  • Carbamazepine
  • Clarithromycin
  • Dexamethasone
  • Diltiazem
  • Dolasetron
  • Granisetron
  • Hormonal contraceptives
  • Itraconazole
  • Ketoconazole
  • Methylprednisolone
  • Nefazodone
  • Nelfinavir
  • Ondansetron
  • Phenytoin
  • Pimozide
  • Rifampin
  • Ritonavir
  • Troleandomycin
  • Warfarin


Do not take EMEND for long periods. It should only be used for short amounts of time when receiving chemotherapy.

Side Effects

EMEND side effects may include the following:

  • Abdominal pain
  • Asthenia
  • Constipation
  • Cough
  • Decreased appetite
  • Decreased white blood cells
  • Dehydration
  • Diarrhea
  • Dizziness
  • Dyspepsia
  • Fatigue
  • Headache
  • Hiccups
  • Hypotension
  • Increased liver enzymes
  • Neutropenia


  1. Emend [package insert]. Whitehouse Station, NC: Merck; 2015.

IMPORTANT NOTE: The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.

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