Elinzanetant

Prescription medicineOnly Available By Prescription

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We guarantee the lowest price on all of our prescription products. If you find your medications cheaper at any other recognized licensed mail order pharmacy, we will not only match their price, we will beat it by 25% of the difference. It is our 125% price match guarantee!

Example: If you find a product on Canada Drugs Direct for $50.00 and find the same product for $40.00 at another mail order pharmacy, we will provide you with a $12.50 discount, bringing your total to $37.50.

To get the discount please make sure to mention the price match to the customer service team when they call to collect payment for your order. Or call toll free at 1-888-904-8467 to place the order through the phone.

Terms & Conditions of Program

  • Guaranteed lowest price is only valid at the time of sale.
  • We will only match the current advertised price.
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  • Products must be authentic in brand and size (same manufacturer, same country of manufacture, same pack size, same strength and same quantity).
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What is a Generic Drug?

A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.

The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.

Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.

Description

Lynkuet (elinzanetant) is a non-hormonal prescription medication used to reduce moderate to severe hot flashes and other menopause-related symptoms. It works by blocking NK-1 and NK-3 receptors in the brain, which play a role in temperature control and vasomotor symptoms. Unlike hormone replacement therapy, Lynkuet does not contain estrogen.

Fact Table

Formula

C33H35F7N4O3

License

US FDA, Health Canada, MHRA, EMA

Bioavailability

Not established

Legal status

Rx-only

Chemical Name

N-[6-[(7S,9aS)-7-(hydroxymethyl)-3,4,6,7,9,9a-hexahydro-1H-pyrazino[2,1-c][1,4]oxazin-8-yl]-4-(4-fluoro-2-methylphenyl)pyridin-3-yl]-2-[3,5-bis(trifluoromethyl)phenyl]-N,2-dimethylpropanamide

Elimination half-life

Approximately 45 hours

Dosage (Strength)

60mg capsules; 120mg orally once daily

Pregnancy

Not indicated in pregnancy

Brands

Lynkuet

Protein binding

99.7%

PubChem CID

16063568

MedlinePlus

N/A

ChEBI

N/A

ATC code

G02CX07

DrugBank

DB18968

KEGG

D12123

Routes of administration

Oral

Directions

This medication is taken orally as two 60 mg soft capsules once daily at bedtime. Patients can take the medication with or without food, and taking it at the same time each day may help maintain consistent levels in the body. The capsule should be swallowed whole with water and shouldn't be crushed or chewed.

Ingredients

Elinzanetant is the active ingredient in this drug.

Cautions

Before taking this medication, you may want to consult a healthcare provider about the following:

  • Any existing health conditions
  • Any allergies
  • A list of all medications currently being taken

Elinzanetant may interact with certain medications. Strong CYP3A4 inhibitors should not be taken with it, and the dose may need to be lowered if used with moderate CYP3A4 inhibitors. Always tell your doctor about all other medicines you are taking.

The safety of elinzanetant has not been established in women with menopause caused by medical treatments or in those with a history of estrogen-related cancers. Your doctor will weigh the potential benefits and risks before prescribing it in these cases.

This medicine can cause fatigue, dizziness, or drowsiness. Avoid driving or operating heavy machinery if you feel these effects while taking it.

Elinzanetant should not be used during pregnancy or while breastfeeding. Animal studies suggest risks to the fetus and drug transfer into milk, though human data are lacking.

This drug is not recommended for people under 18 or over 65 years old, as safety and effectiveness have not been studied in these groups.

Contraindications

Avoid taking this medication if any of the following apply:

  • Hypersensitivity to any formulation ingredient
  • Concomitant use of strong CYP3A4 inhibitors
  • Known or suspected pregnancy

Side Effects

The most common side effects of Lynkuet seen in studies were headache, tiredness, and sleepiness. Some people also reported stomach discomfort, diarrhea, dizziness, muscle spasms, or rash. These side effects were usually mild to moderate and happened more often than in those given a placebo.

More serious side effects were uncommon, though some people stopped treatment because of fatigue, headache, diarrhea, or stomach pain. Rare cases of sensitivity to sunlight have been reported, but it’s unclear how significant this is. Less frequent side effects included palpitations, mood changes, ringing in the ears, and changes in blood tests such as thyroid or blood sugar levels.

References



IMPORTANT NOTE: The information provided above is for general awareness and educational purposes only. It is not intended to diagnose, treat, or replace professional medical or veterinary advice. Always consult your physician, pharmacist, or veterinarian regarding the safety, suitability, and proper use of any medication for yourself or your pet.

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