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E.E.S. granules (Erythromycin)

Prescription medicineOnly Available By Prescription

Top brand choice

Strength Pack Size Qty
200mg/5ml 100 ml
Pack Size
200mg/5ml 200 ml
Pack Size

You'll have option to make 4 interest-free payments by credit card once your order is confirmed using

Top Generic choice

Strength Pack Size Qty
200mg/5ml 100 ml
Pack Size
200mg/5ml 200 ml
Pack Size

You'll have option to make 4 interest-free payments by credit card once your order is confirmed using

What if I find a lower price with another pharmacy?

We guarantee the lowest price on all of our prescription products. If you find your medications cheaper at any other recognized licensed mail order pharmacy, we will not only match their price, we will beat it by 25% of the difference. It is our 125% price match guarantee!

Example: If you find a product on Canada Drugs Direct for $50.00 and find the same product for $40.00 at another mail order pharmacy, we will provide you with a $12.50 discount, bringing your total to $37.50.

To get the discount please make sure to mention the price match to the customer service team when they call to collect payment for your order. Or call toll free at 1-888-904-8467 to place the order through the phone.

Terms & Conditions of Program

  • Guaranteed lowest price is only valid at the time of sale.
  • We will only match the current advertised price.
  • Products must be identical and in stock at the time of placing an order with a licensed mail order pharmacy. The must be a member of CIPA (Canadian International Pharmacy Association).
  • Products must be authentic in brand and size (same manufacturer, same country of manufacture, same pack size, same strength and same quantity).
  • Products must be new. We cannot match the price of any used, short expiry or expired product.
  • Price match can only be issued over the phone with our customer service team
What is a Generic Drug?

A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.

The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.

Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.


E.E.S. granules is a type of oral liquid suspension that your doctor can prescribe to treat the following:

  • Acute pelvic inflammatory disease
  • Chlamydia
  • Diphtheria
  • Legionnaires' Disease
  • Listeriosis
  • Lower respiratory tract infection
  • Mild to moderate upper respiratory tract infections
  • Pertussis
  • Skin and skin structure infections
  • Syphilis

E.E.S. granules works by inhibiting RNA-dependent protein synthesis while the bacteria genetic code is being copied. It binds to the 50S ribosomal subunit resulting in blockage of transpeptidation.

Fact Table






30% - 65%

Legal status


Chemical Name


Elimination half-life

1.5 hours

Dosage (Strength)

200mg/5ml 100 ml, 200mg/5ml 200 ml




E.E.S. granules

Protein binding


PubChem CID






ATC code






Routes of administration



Take E.E.S. granules exactly as prescribed by your healthcare provider. The dosage, frequency, and length of therapy will vary greatly based on what is being treated.


The active ingredient in E.E.S. granules is erythromycin.


The most common drug-drug interactions with this medication can include:2

  • Abametapir
  • Amiodarone
  • Aprepitant
  • Astemizole
  • Asunaprevir
  • BCG (Intravesical)
  • Bosutinib
  • Budesonide (Topical)
  • Cholera Vaccine
  • Cisapride
  • Domperidone
  • DOXOrubicin 
  • Dronedarone
  • Eletriptan
  • Entrectinib
  • Ergot Derivatives
  • Flibanserin
  • Fluconazole
  • Fosaprepitant
  • Fusidic Acid
  • Infigratinib
  • Ivabradine
  • Lemborexant
  • Levoketoconazole
  • Lomitapide
  • Lonafarnib
  • Lovastatin
  • Mizolastine
  • PAZOPanib
  • Neratinib
  • Pimozide
  • Pralsetinib
  • QT-prolonging Class III Antiarrhythmics
  • QuiNIDine
  • Red Yeast Rice
  • Saquinavir
  • Simeprevir
  • Sirolimus 
  • Terfenadine
  • Topotecan
  • VinCRIStine 


Erythromycin and similar medications can cause abnormalities in the heart rhythm. Tell your doctor if you have a history of heart conditions.

Use caution if you have a history of liver disease.

Use extreme caution if you have a diagnosis of myasthenia gravis before taking this drug.

Some dosage forms contain benzyl alcohol, which can cause toxicity in young infants.

Side Effects

Erythromycin side effects can include:

  •  Abdominal pain
  • Abnormal liver function tests
  • Anaphylaxis
  • Anorexia
  • Diarrhea
  • Erythema multiforme
  • Hearing loss
  • Hepatitis
  • Interstitial nephritis
  • Nausea
  • Oral candidiasis
  • Pancreatitis
  • Pruritus
  • Pseudomembranous colitis
  • QTc prolongation
  • Seizure
  • Skin rash
  • Stevens-Johnson syndrome
  • Torsade de Pointes
  • Toxic epidermal necrosis
  • Urticaria
  • Ventricular arrhythmia
  • Ventricular tachycardia
  • Vomiting
  • Weakness


E.E.S. [package insert]. Atlanta, GA: Arbor Pharmaceuticals; 2012.

IMPORTANT NOTE: The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.

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