Durolane (Sodium Hyaluronate)

Prescription medicineOnly Available By Prescription

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Strength Pack Size Qty
60mg 3ml
Pack Size

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What if I find a lower price with another pharmacy?

We guarantee the lowest price on all of our prescription products. If you find your medications cheaper at any other recognized licensed mail order pharmacy, we will not only match their price, we will beat it by 25% of the difference. It is our 125% price match guarantee!

Example: If you find a product on Canada Drugs Direct for $50.00 and find the same product for $40.00 at another mail order pharmacy, we will provide you with a $12.50 discount, bringing your total to $37.50.

To get the discount please make sure to mention the price match to the customer service team when they call to collect payment for your order. Or call toll free at 1-888-904-8467 to place the order through the phone.

Terms & Conditions of Program

  • Guaranteed lowest price is only valid at the time of sale.
  • We will only match the current advertised price.
  • Products must be identical and in stock at the time of placing an order with a licensed mail order pharmacy. They must be an online Canadian pharmacy with an address in Canada.
  • Products must be authentic in brand and size (same manufacturer, same country of manufacture, same pack size, same strength and same quantity).
  • Products must be new. We cannot match the price of any used, short expiry or expired product.
  • Price match can only be issued over the phone with our customer service team. Please note at this time we cannot offer price matching for the products Ozempic or Saxenda.
What is a Generic Drug?

A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.

The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.

Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.


Durolane is a medicated injection used by patients who did not experience improvement with non-pharmacological therapies or simple pain relievers such as acetaminophen to relieve pain due to osteoarthritis of the knee.

Sodium hyaluronate that helps lubricate and cushion the knee joints is contained in Durolane injection; this provides pain relief.


If you have any questions or concerns about Durolane, talk to your doctor. You and your doctor should discuss your treatment schedule. 

Durolane 60 mg/3 mL comes in 3 mL pre-filled syringes. Each mL of Durolane contains 20 mg of stabilized sodium hyaluronate. One syringe of Durolane should be injected into the knee joint. 


One pre-filled syringe includes 20 mg of stabilized sodium hyaluronate per mL. Sodium chloride, potassium dihydrogen phosphate, disodium hydrogen phosphate dihydrate, and water for injection are other included ingredients.


Do not use Durolane injections if you have infections in the knee joint; also, do not use Durolane if you have infections or diseases at the injection site of the skin.

Avoid using Durolane injections if you have an allergy to sodium hyaluronate or any of the other ingredients contained in the medication.


  • Before beginning treatment with Durolane, tell your doctor:
    • About any allergies you may have
    • About any medications you take 
    • If you have any health problems or conditions 
    • If you are currently pregnant or breastfeeding
  • When using Durolane, strict aseptic administration technique is recommended.
  • Each Durolane injection is a single-dose. The injection must be used once the package is opened. Do not re-use Durolane injections. Properly dispose of any syringes and unused Durolane.
  • If the syringe blister package is opened or damaged, do not use.
  • You should not use skin disinfectants that contain quaternary ammonium salts.
  • Do not inject Durolane into blood vessels, outside of the joint, or into the synovial tissue or capsule. 
  • Use caution while using Durolane if you have pre-existing chondrocalcinosis; the injection could cause an attack.
  • Avoid participating in strenuous or prolonged weight-bearing activities within 48 hours of receiving a Durolane injection.
  • Pain or swelling of the affected knee joint after receiving a Durolane injection may occur.
  • Store Durolane at temperatures between 32°F-86° F (0°F-30° C).

Side Effects

Immediately tell your doctor If you develop troublesome or persistent side effects. Pain at the injection site and swelling and pain at the joint are side effects associated with Durolane. 


Durolane Instructions for Use. Durham, NC: Bioventus LLC.

IMPORTANT NOTE: The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.

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