Canada Drugs Direct

Visiting from Canada?

Want to save up to 80% on your medications? Signup below to be notified if we open a Canadian Online Pharmacy.

I agree to receive email updates from Canada Drugs Direct

Looking for Call us toll free 1-800-500-2897

Durezol (difluprednate) Ophthalmic Emulsion

Prescription medicineOnly Available By Prescription

Top brand choice

Strength Pack Size Qty
Pack Size

You'll have option to make 4 interest-free payments by credit card once your order is confirmed using

Top Generic choice

Strength Pack Size Qty
Pack Size

You'll have option to make 4 interest-free payments by credit card once your order is confirmed using

What if I find a lower price with another pharmacy?

We guarantee the lowest price on all of our prescription products. If you find your medications cheaper at any other recognized licensed mail order pharmacy, we will not only match their price, we will beat it by 25% of the difference. It is our 125% price match guarantee!

Example: If you find a product on Canada Drugs Direct for $50.00 and find the same product for $40.00 at another mail order pharmacy, we will provide you with a $12.50 discount, bringing your total to $37.50.

To get the discount please make sure to mention the price match to the customer service team when they call to collect payment for your order. Or call toll free at 1-888-904-8467 to place the order through the phone.

Terms & Conditions of Program

  • Guaranteed lowest price is only valid at the time of sale.
  • We will only match the current advertised price.
  • Products must be identical and in stock at the time of placing an order with a licensed mail order pharmacy. The must be a member of CIPA (Canadian International Pharmacy Association).
  • Products must be authentic in brand and size (same manufacturer, same country of manufacture, same pack size, same strength and same quantity).
  • Products must be new. We cannot match the price of any used, short expiry or expired product.
  • Price match can only be issued over the phone with our customer service team
What is a Generic Drug?

A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.

The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.

Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.


Durozel is a prescription eye drop that contains a steroid medication. It can be used to treat:

  • Pain and inflammation after ocular (eye) surgery
  • Endogenous anterior uveitis

After surgery, the eye becomes inflamed as part of the healing process. However, symptoms of inflammation can be painful and irritating. Durezol works like other corticosteroids to reduce the response of the immune system and reduce these symptoms.

Anterior uveitis can be caused by multiple things, including a side effect of medication, eye injury, animal scratches, infections, or autoimmune disorders. Durezol reduces the inflammation associated with this condition.

Fact Table







Legal status


Chemical Name


Elimination half-life


Dosage (Strength)



No Known Risk



Protein binding


PubChem CID






ATC code






Routes of administration

Eye drops


The standard dosages are as follows:

  • Pain and inflammation after ocular (eye) surgery: 1 drop into the affected eye four times daily for two weeks, and then two times daily for another two weeks
  • Endogenous anterior uveitis: 1 drop into the affected eye four times daily for two weeks

Do not touch the tip of the eyedropper to the eye to avoid bacterial contamination of the bottle.


The active ingredient in this medication is difluprednate.


Durezol can interact with the following eye medications:

  • Acular
  • Acular LS
  • Acuvail
  • Bromfenac ophthalmic
  • BromSite
  • Diclofenac ophthalmic
  • Flurbiprofen ophthalmic
  • Ilevro
  • Ketorolac ophthalmic
  • Ketorolac/phenylephrine ophthalmic
  • Nepafenac ophthalmic
  • Nevanac
  • Omidria
  • Prolensa
  • Voltaren Ophthalmic


Wait 15 minutes after applying this medication before putting in contact lenses.

If used after surgery, the same bottle should not be used for both eyes.

Side Effects

The most common Durezol eye drops side effects include:

  • Anterior chamber inflammation
  • Blepharitis
  • Blurred vision
  • Cataract
  • Conjunctival edema
  • Corneal edema 
  • Crusting of the eyelid
  • Decreased visual acuity
  • Dry eye syndrome
  • Eye irritation
  • Eye pain
  • Eye pruritus 
  • Headache
  • Increased intraocular pressure
  • Increased lacrimation
  • Ocular hyperemia
  • Photophobia
  • Uveitis


  1. Durezol [package insert]. East Hanover, NJ: Novartis; 2020.

IMPORTANT NOTE: The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.

product-reviews Product Reviews