Dupixent (Dupilumab)

Prescription medicineOnly Available By Prescription

What if I find a lower price with another pharmacy?

We guarantee the lowest price on all of our prescription products. If you find your medications cheaper at any other recognized licensed mail order pharmacy, we will not only match their price, we will beat it by 25% of the difference. It is our 125% price match guarantee!

Example: If you find a product on Canada Drugs Direct for $50.00 and find the same product for $40.00 at another mail order pharmacy, we will provide you with a $12.50 discount, bringing your total to $37.50.

To get the discount please make sure to mention the price match to the customer service team when they call to collect payment for your order. Or call toll free at 1-888-904-8467 to place the order through the phone.

Terms & Conditions of Program

  • Guaranteed lowest price is only valid at the time of sale.
  • We will only match the current advertised price.
  • Products must be identical and in stock at the time of placing an order with a licensed mail order pharmacy. They must be an online Canadian pharmacy with an address in Canada.
  • Products must be authentic in brand and size (same manufacturer, same country of manufacture, same pack size, same strength and same quantity).
  • Products must be new. We cannot match the price of any used, short expiry or expired product.
  • Price match can only be issued over the phone with our customer service team. Please note at this time we cannot offer price matching for the products Ozempic or Saxenda.
What is a Generic Drug?

A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.

The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.

Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.

Description

Dupixent (dupilumab) is available as a subcutaneous injection for the treatment of atopic dermatitis, asthma, chronic rhinosinusitis with nasal polyps, eosinophilic esophagitis, and prurigo nodularis.

Dupixent single-dose prefilled syringes with needle shields are available in the following concentrations:

  • 300 mg/2 mL
  • 200 mg/1.14 mL
  • 100 mg/0.67 mL

Dupixent single-dose prefilled pens are available in the following strengths:

  • 300 mg/2 mL
  • 200 mg/1.14 mL

Fact Table

Formula

C6512H10066N1730O2052S46

License

US DailyMed, US FDA

Bioavailability

Dupilumab is administered by injection and does not have a specific bioavailability value since it acts systemically

Legal status

Rx-only

Chemical Name

Dupilumab

Elimination half-life

The elimination half-life of dupilumab is approximately 26 days

Dosage (Strength)

Typically ranging from 150 mg to 300 mg

Pregnancy

Consult Doctor

Brands

Dupixent is the primary brand name for dupilumab

Protein binding

Dupilumab does not significantly bind to plasma proteins

PubChem CID

Not available because this is not a discrete structure

MedlinePlus

a617021

ChEBI

The ChEBI (Chemical Entities of Biological Interest) entry for dupilumab is not available as it is a protein-based drug

ATC code

D11AH05

DrugBank

DB12159

KEGG

D10354

Routes of administration

Dupilumab is administered by subcutaneous injection

Directions

Dupixent should be administered as directed by your doctor. Contact your doctor or pharmacy about any questions or concerns that arise.

Dupixent dosing depends on the condition being treated. Weight is also taken into consideration when dosing for pediatric patients.

Information regarding how to inject Dupixent, how much to inject, and how often to inject will be provided to you by your doctor.

Ingredients

The active ingredient in Dupixent is dupilumab. L-arginine hydrochloride, L-histidine, polysorbate 80, sodium acetate, sucrose, and water for injection are the inactive ingredients included.

Contraindications

Dupixent should not be administered to patients who are allergic to any of its ingredients or excipients.

Cautions

  • Before you start treatment with Dupixent injections, inform your doctor of:
    • All the medications you take
    • Your allergies
    • Your current health problems and past medical history
    • Your pregnancy or breastfeeding status
  • Hypersensitivity reactions, including anaphylaxis, serum sickness, swelling underneath the skin, hives, rash, tender bumps under the skin, and skin lesions, may occur during treatment with Dupixent. Seek immediate medical care if you develop any of these reactions.
  • Eye problems may occur during treatment with Dupixent. Call your doctor immediately if you have eye symptoms.
  • Call your doctor immediately if you develop a rash, worsening pulmonary symptoms, and/or nerve pain.
  • Corticosteroids should not be stopped abruptly when you start Dupixent treatment. Slow taper off steroids.
  • Call your doctor immediately if you have problems with your joints during treatment with Dupixent.
  • Be sure to receive treatment for helminth infections before you begin using Dupixent.
  • Patients on Dupixent should not receive live vaccines.

Side Effects

Conjunctivitis, blepharitis, oral herpes, keratitis, itchy eyes, other herpes simplex virus infection, dry eye, eosinophilia, injection site reactions, mouth or throat pain, problems sleeping, toothache, gastritis, joint pain, and upper respiratory tract infections are some Dupixent side effects; however, these are not the only side effects that can occur. If you have side effects that bother you or won’t go away, contact your doctor.

Searching for a competitive Dupixent cost? You can buy Dupixent injections online at a competitive price and with a valid prescription from your doctor at Canada Drugs Direct.

Reference:

  1. Dupixent. Tarrytown, NY: Regeneron Pharmaceuticals, Inc.; 2022.



IMPORTANT NOTE: The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.

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