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Doryx (Doxycycline Hyclate)

Prescription medicineOnly Available By Prescription

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What if I find a lower price with another pharmacy?

We guarantee the lowest price on all of our prescription products. If you find your medications cheaper at any other recognized licensed mail order pharmacy, we will not only match their price, we will beat it by 25% of the difference. It is our 125% price match guarantee!

Example: If you find a product on Canada Drugs Direct for $50.00 and find the same product for $40.00 at another mail order pharmacy, we will provide you with a $12.50 discount, bringing your total to $37.50.

To get the discount please make sure to mention the price match to the customer service team when they call to collect payment for your order. Or call toll free at 1-888-904-8467 to place the order through the phone.

Terms & Conditions of Program

  • Guaranteed lowest price is only valid at the time of sale.
  • We will only match the current advertised price.
  • Products must be identical and in stock at the time of placing an order with a licensed mail order pharmacy. The must be a member of CIPA (Canadian International Pharmacy Association).
  • Products must be authentic in brand and size (same manufacturer, same country of manufacture, same pack size, same strength and same quantity).
  • Products must be new. We cannot match the price of any used, short expiry or expired product.
  • Price match can only be issued over the phone with our customer service team
What is a Generic Drug?

A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.

The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.

Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.


Doryx is an antibacterial medication that your healthcare provider may prescribe to treat a variety of conditions that are caused by bacterial infection

Doryx is most commonly prescribed to treat long-term acne. Acne is a skin condition where red, bumpy, sometimes painful spots appear on the skin of the face. Acne is most common in teenagers but may be present in adults as well. It can be long-term or resolve quickly on its own.

It is unclear how Doryx helps to treat acne, but it is thought that bacteria are one of the causes of moderate to severe acne.


The usual dosage of Doryx is 100 mg twice daily on the first day, and then 100 mg by mouth once daily.

The doctor may increase the dose to 100 mg twice daily if the acne is severe.

Take Doryx with a full glass of water.

Take Doryx 1 hour before or 2 hours after a meal. Avoid taking it with multivitamins that contain minerals or foods that are high in calcium.


The active ingredient in Doryx is doxycycline hyclate delayed-release.


Tell your doctor and pharmacist about all medications you are taking before starting Doryx, especially:

  • Aminolevulinic Acid
  • Antacids
  • Barbiturates
  • BCG
  • Bile Acid Sequestrants
  • Bismuth Subsalicylate
  • Calcium Salts
  • Carbamazepine
  • Cholera Vaccine
  • Fosphenytoin
  • Iron Preparations
  • Lithium
  • Mecamylamine
  • Methoxyflurane
  • Multivitamins
  • Penicillin
  • Proton Pump Inhibitors
  • Quinapril
  • Sucralfate
  • Typhoid Vaccine
  • Warfarin


Wear sun protection while using Doryx because it can increase your sensitivity to the sun.

Side Effects

Doryx side effects can include:

  • Abdominal distention
  • Abdominal pain
  • Anorexia
  • Bone growth suppression
  • Diarrhea
  • Drug reaction with eosinophilia and systemic symptoms (DRESS)
  • Erythematous rash
  • Erythema multiforme
  • Esophageal injury
  • Increased blood urea nitrogen
  • Increased lactate dehydrogenase
  • Increased serum glucose
  • Photosensitivity
  • Stevens-Johnson syndrome
  • Upper abdominal pain
  • Vulvovaginal candidiasis
  • Xerostomia


Doryx [package insert]. Rockaway, NJ: Warner Chilcott; 2013.

IMPORTANT NOTE: The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.

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