Dolmatil (Sulpiride)

Prescription medicineOnly Available By Prescription

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What if I find a lower price with another pharmacy?

We guarantee the lowest price on all of our prescription products. If you find your medications cheaper at any other recognized licensed mail order pharmacy, we will not only match their price, we will beat it by 25% of the difference. It is our 125% price match guarantee!

Example: If you find a product on Canada Drugs Direct for $50.00 and find the same product for $40.00 at another mail order pharmacy, we will provide you with a $12.50 discount, bringing your total to $37.50.

To get the discount please make sure to mention the price match to the customer service team when they call to collect payment for your order. Or call toll free at 1-888-904-8467 to place the order through the phone.

Terms & Conditions of Program

  • Guaranteed lowest price is only valid at the time of sale.
  • We will only match the current advertised price.
  • Products must be identical and in stock at the time of placing an order with a licensed mail order pharmacy. They must be an online Canadian pharmacy with an address in Canada.
  • Products must be authentic in brand and size (same manufacturer, same country of manufacture, same pack size, same strength and same quantity).
  • Products must be new. We cannot match the price of any used, short expiry or expired product.
  • Price match can only be issued over the phone with our customer service team. Please note at this time we cannot offer price matching for the products Ozempic or Saxenda.
What is a Generic Drug?

A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.

The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.

Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.


Your doctor may prescribe Dolmatil to treat various psychiatric disorders, particularly schizophrenia. The active component of Dolmatil is sulpiride, an atypical antipsychotic that works by balancing the levels of neurotransmitters in the brain, specifically dopamine and serotonin. 

For people diagnosed with schizophrenia, they have abnormal levels of dopamine and serotonin in various parts of the brain. Dolmatil regulates neurotransmitters and helps alleviate the symptoms associated with schizophrenia.


The starting dosage is usually 400-800 mg by mouth once daily.

The dosage may be adjusted if you have a history of kidney problems.

Do not drink alcohol while taking Dolmatil.


The active ingredient in Dolmatil is sulpiride.


Some of the most common drug-drug interactions may include:

  • Aclidinium
  • Amiodarone
  • Apomorphine
  • Atazanavir
  • Atropine
  • Benztropine
  • clarithromycin
  • Clotrimazole
  • Cyclosporine
  • Darifenacin
  • Dicyclomine
  • Digoxin
  • Erythromycin
  • Erythromycin
  • Fesoterodine
  • Flavoxate
  • Fluconazole
  • Fluconazole
  • Glycopyrrolate
  • Hyoscyamine
  • Ipratropium
  • Itraconazole
  • Ketoconazole
  • Methscopolamine
  • Oxybutynin
  • Paroxetine
  • Posaconazole
  • Propantheline
  • Quinidine
  • Quinupristin/dalfopristin
  • Ritonavir
  • Scopolamine
  • Solifenacin
  • Telithromycin
  • Tiotropium
  • Tolterodine
  • Trihexyphenidyl
  • Trospium
  • Umeclidinium
  • Voriconazole


Tell your prescribing doctor about any pre-existing medical conditions, allergies, or medications you are currently taking, including over-the-counter drugs and herbal supplements. 

Certain medical conditions and medications may interact with Dolmatil, potentially leading to adverse effects or compromising efficacy.

Dolmatil may cause drowsiness or dizziness, impairing the ability to perform tasks requiring alertness. Refrain from driving, operating heavy machinery, or engaging in activities that demand mental acuity when starting this drug.

Do not discontinue Dolmatil abruptly, as this can lead to withdrawal symptoms or a relapse of symptoms. If you have any concerns or questions regarding the medication, discuss them with your healthcare provider for proper guidance and support.

Side Effects

The most common side effects of this drug include.

  • Akathisia
  • Allergic reactions
  • Anxiety
  • Blurred vision
  • Constipation
  • Decreased libido
  • Diarrhea
  • Dizziness
  • Drowsiness
  • Dry mouth
  • Dystonia
  • Erectile dysfunction
  • Extrapyramidal symptoms
  • Headache
  • Hyperprolactinemia
  • Increased appetite
  • Increased salivation
  • Insomnia
  • Irregular menstrual periods
  • Muscle stiffness
  • Nausea
  • Parkinsonism
  • Restlessness
  • Skin rash
  • Tremors
  • Vomiting
  • Weight gain


Domatil [package insert]. Quetigny, France: Sanofi; 2014.

IMPORTANT NOTE: The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.

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