Canada Drugs Direct

Visiting from Canada?

Want to save up to 80% on your medications? Signup below to be notified if we open a Canadian Online Pharmacy.

I agree to receive email updates from Canada Drugs Direct

Looking for Call us toll free 1-800-500-2897

Diamicron MR (Gliclazide MR)

Also Known as Diamicron XR (Gliclazide XR)

Prescription medicineOnly Available By Prescription

Top brand choice

Strength Pack Size Qty
Pack Size
Pack Size

You'll have option to make 4 interest-free payments by credit card once your order is confirmed using

Top Generic choice

Strength Pack Size Qty
Pack Size
Pack Size

You'll have option to make 4 interest-free payments by credit card once your order is confirmed using

What if I find a lower price with another pharmacy?

We guarantee the lowest price on all of our prescription products. If you find your medications cheaper at any other recognized licensed mail order pharmacy, we will not only match their price, we will beat it by 25% of the difference. It is our 125% price match guarantee!

Example: If you find a product on Canada Drugs Direct for $50.00 and find the same product for $40.00 at another mail order pharmacy, we will provide you with a $12.50 discount, bringing your total to $37.50.

To get the discount please make sure to mention the price match to the customer service team when they call to collect payment for your order. Or call toll free at 1-888-904-8467 to place the order through the phone.

Terms & Conditions of Program

  • Guaranteed lowest price is only valid at the time of sale.
  • We will only match the current advertised price.
  • Products must be identical and in stock at the time of placing an order with a licensed mail order pharmacy. The must be a member of CIPA (Canadian International Pharmacy Association).
  • Products must be authentic in brand and size (same manufacturer, same country of manufacture, same pack size, same strength and same quantity).
  • Products must be new. We cannot match the price of any used, short expiry or expired product.
  • Price match can only be issued over the phone with our customer service team
What is a Generic Drug?

A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.

The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.

Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.


Your doctor may prescribe Diamicron MR to treat high blood sugar if you have type 2 diabetes. This medication contains gliclazide, which falls under the sulfonylurea class of drugs, and it helps to lower blood sugar by increasing insulin secretion from pancreatic beta cells.

Elevated blood sugar is a common concern in diabetes, and uncontrolled levels can lead to various health complications, including damage to the blood vessels of the eyes, kidneys, and nerves. Gliclazide stimulates the pancreas to release insulin, which, in turn, assists in glucose uptake by the body's cells.


The starting dosage is 40-80 mg by mouth once daily, with the largest meal of the day.

Your doctor may increase the dosage by 40-80 mg daily every 1-4 weeks. The maximum dosage is 320 mg daily.


The active ingredient is gliclazide MR.


Common drug-drug interactions with Diamicron MR may include:

  • Acarbose
  • Albiglutide
  • Alcohol (Ethyl)
  • Alogliptin
  • Alpelisib
  • Alpha-Lipoic Acid
  • Aminolevulinic Acid (Systemic)
  • Aminolevulinic Acid (Topical)
  • Amiodarone
  • Atenolol
  • Bisoprolol
  • Bortezomib
  • Canagliflozin
  • Carbocisteine
  • Carvedilol
  • Chloramphenicol (Systemic)
  • Citalopram
  • Clarithromycin
  • Dapagliflozin
  • Dipeptidyl Peptidase-IV Inhibitors
  • Direct Acting Antiviral Agents (HCV)
  • Dulaglutide
  • Empagliflozin
  • Ertugliflozin
  • Escitalopram
  • Etilefrine
  • Exenatide
  • Fibric Acid Derivatives
  • Fluconazole
  • Fluoxetine
  • Fluvastatin
  • Fluvoxamine
  • Glucagon-Like Peptide-1 Agonists
  • Guanethidine
  • Herbal Products with Glucose Lowering Effects
  • Labetalol
  • Linagliptin
  • Liraglutide
  • Lumacaftor and Ivacaftor
  • Maitake
  • Methoxsalen (Systemic)
  • Metoprolol
  • Miconazole (Oral)
  • Miglitol
  • Mitiglinide
  • Monoamine Oxidase Inhibitors
  • Nebivolol
  • Omeprazole
  • Paroxetine
  • Pegvisomant
  • Phenobarbital
  • Porfimer
  • Probenecid
  • Propranolol
  • Prothionamide
  • Quinolones
  • Rifampin
  • Rifapentine
  • Ritodrine
  • Salicylates
  • Saxagliptin
  • Selective Serotonin Reuptake Inhibitors
  • Semaglutide
  • Sertraline
  • Sitagliptin
  • Sotalol
  • St John's Wort
  • Sulfonamide Antibiotics
  • Tetracyclines
  • Thiazide and Thiazide-Like Diuretics
  • Thiazolidinediones
  • Valproic acid
  • Verteporfin
  • Voriconazole
  • Warfarin


Individuals with a history of sulfonamide allergies should inform their doctor.

Before starting Diamicron MR, tell your doctor if you have a history of liver disease or specific blood disorders. 

Blood glucose should be regularly monitored while on this medication, and any significant changes or concerns should be discussed with your healthcare provider. 

Do not adjust the dosage or discontinue Diamicron MR unless under the guidance of a healthcare professional. 

Side Effects

Common side effects may include:

  • Abdominal discomfort
  • Abnormal liver function
  • Blood disorders
  • Blurred vision
  • Diarrhea
  • Difficulty breathing
  • Hypoglycemia (low blood sugar)
  • Indigestion
  • Itching
  • Nausea
  • Rashes
  • Swelling
  • Weight gain


Diamicron MR [package insert]. Laval, Quebec: Servier Canada; 2019.

IMPORTANT NOTE: The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.

product-reviews Product Reviews