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Descovy (Emtricitabine / Tenofovir)

Prescription medicineOnly Available By Prescription

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What if I find a lower price with another pharmacy?

We guarantee the lowest price on all of our prescription products. If you find your medications cheaper at any other recognized licensed mail order pharmacy, we will not only match their price, we will beat it by 25% of the difference. It is our 125% price match guarantee!

Example: If you find a product on Canada Drugs Direct for $50.00 and find the same product for $40.00 at another mail order pharmacy, we will provide you with a $12.50 discount, bringing your total to $37.50.

To get the discount please make sure to mention the price match to the customer service team when they call to collect payment for your order. Or call toll free at 1-888-904-8467 to place the order through the phone.

Terms & Conditions of Program

  • Guaranteed lowest price is only valid at the time of sale.
  • We will only match the current advertised price.
  • Products must be identical and in stock at the time of placing an order with a licensed mail order pharmacy. The must be a member of CIPA (Canadian International Pharmacy Association).
  • Products must be authentic in brand and size (same manufacturer, same country of manufacture, same pack size, same strength and same quantity).
  • Products must be new. We cannot match the price of any used, short expiry or expired product.
  • Price match can only be issued over the phone with our customer service team
What is a Generic Drug?

A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.

The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.

Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.


Your doctor may prescribe Descovy to suppress the infection caused by HIV (human immunodeficiency virus). HIV is a chronic infection that slowly attacks the immune system, slowly leading to potentially fatal infections. HIV can be appropriately suppressed with the long-term use of antiviral agents.

Descovy contains two different medications that work by preventing HIV viruses from replicating. Stopping replication gives the immune system a chance to manage the infection and prevent symptoms.


Take Descovy once daily, exactly as prescribed by your doctor. It can be taken with or without food.

Missing dosages can increase the risk of developing resistant strains of the virus, making Descovy less effective. 


The active ingredients are tenofovir 200 mg and emtricitabine 25 mg.


Descovy has many potential interactions with other medications. It can also react to over-the-counter (OTC) drugs, herbals, and supplements. Use caution if you are taking any of the following:

  • Acyclovir-Valacyclovir
  • Adefovir
  • Aminoglycosides
  • Cabozantinib
  • Carbamazepine
  • Cidofovir
  • Cladribine
  • Cobicistat
  • Fosphenytoin-Phenytoin
  • Ganciclovir-Valganciclovir
  • Nonsteroidal Anti-Inflammatory Drugs
  • Orlistat
  • Oxcarbazepine
  • Phenobarbital
  • Primidone
  • Rifabutin
  • Rifampin
  • Rifapentine
  • Ritonavir
  • St John's Wort
  • Tipranavir


Tell your doctor if you have a history of kidney or liver problems before taking this medication.

When starting Descovy, some patients are at risk of developing immune reconstitution syndrome. This occurs before the immune system suddenly becomes more active once treatment starts. Symptoms may include fever, lymphadenopathy, and worsening existing infections.

Tell your doctor if you have a history of lactic acidosis before starting Descovy.

Side Effects

Descovy side effects may include the following:

  • Abdominal pain
  • Decreased bone mineral density
  • Exacerbation of hepatitis B
  • Fanconi's syndrome
  • Fatigue
  • Headache
  • Increased serum triglycerides
  • Proximal tubular nephropathy
  • Skin rash urticaria


Descovy [package insert]. Foster City, CA: Gilead; 2021.

IMPORTANT NOTE: The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.

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