Deramaxx (Deracoxib)

Also Known as Deramaxx (Deracoxib)

Prescription medicineOnly Available By Prescription

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We guarantee the lowest price on all of our prescription products. If you find your medications cheaper at any other recognized licensed mail order pharmacy, we will not only match their price, we will beat it by 25% of the difference. It is our 125% price match guarantee!

Example: If you find a product on Canada Drugs Direct for $50.00 and find the same product for $40.00 at another mail order pharmacy, we will provide you with a $12.50 discount, bringing your total to $37.50.

To get the discount please make sure to mention the price match to the customer service team when they call to collect payment for your order. Or call toll free at 1-888-904-8467 to place the order through the phone.

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  • Guaranteed lowest price is only valid at the time of sale.
  • We will only match the current advertised price.
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What is a Generic Drug?

A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.

The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.

Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.


Deramaxx (deracoxib) is for use in dogs only by or on the order of a licensed veterinarian to manage pain and inflammation caused by osteoarthritis. It is also used in dogs to manage pain and inflammation associated with orthopedic and dental surgeries.

Fact Table







Legal status


Chemical Name


Elimination half-life

3 hours

Dosage (Strength)

12mg, 25mg, 75mg, 100mg


Not recommended



Protein binding

More than 90%

PubChem CID






ATC code






Routes of administration



Deramaxx comes in 12 mg, 25 mg, 75 mg, and 100 mg chewable, beefy-flavored tablets. If your dog's dose is less than 12 mg, the 12 mg tablet can be cut in half to provide a 6 mg dose. Talk to your veterinarian about how to give an accurate dose to your dog using the tablets. 

The instructions that are supplied with your dog's Deramaxx prescription should be followed. Talk to your veterinarian or pharmacist about any questions you may have about the medication.

Dosing for pain and inflammation in dogs caused by osteoarthritis:

0.45 mg to 0.91 mg per pound per day (1 mg to 2 mg per kg per day) as a single dose, as needed

Dosing for pain and inflammation in dogs after orthopedic surgery:

1.4 mg to 1.8 mg per pound per day (3 mg to 4 mg per kg per day) as a single dose, as needed. Do not administer for more than 7 days.

Dosing for pain and inflammation in dogs after dental surgery:

0.45 mg to 0.91 mg per pound per day (1 mg to 2 mg per kg per day) as a single dose for 3 days. Give the first dose one hour before dental surgery. Give the remaining doses once daily for up to two days.

You may give Deramaxx to your dog after your dog has eaten a meal (preferred) or you may give it without food. 


The active ingredient in Deramaxx is deracoxib.


Do not give your dog Deramaxx if your dog has an allergy to deracoxib.


  • Before you give Deramaxx to your dog, discuss the following with your veterinarian:
    • Your dog's medications or supplements
    • Your dog's allergies or history of allergic reactions to medications, including other NSAIDs
    • Your dog's medical conditions
    • Your dog's history of stomach problems
    • Your dog's history of kidney problems
    • If your dog is pregnant or if you plan to breed your dog
    • If your dog is nursing
  • Deramaxx should only be given to dogs. Avoid use in humans or cats.

Side Effects

Vomiting, diarrhea, weight loss, seizures, pyoderma, dermatitis, unilateral conjunctivitis, blood in the urine, urinary tract infection, enlarged spleen, and grade II murmur systolic can occur with the use of Deramaxx. These may not be the only side effects that can occur during treatment with Deramaxx. Watch for side effects and immediately inform your veterinarian of any troublesome or persistent side effects that develop in your dog.


Deramaxx (deracoxib) for oral use in dogs only. Greenfield, IN: Elanco US Inc.

IMPORTANT NOTE: The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.

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