Daypro (Oxaprozin)

Prescription medicineOnly Available By Prescription

Top brand choice

Strength Pack Size Qty
Pack Size

You'll have option to make 4 interest-free payments by credit card once your order is confirmed using

What if I find a lower price with another pharmacy?

We guarantee the lowest price on all of our prescription products. If you find your medications cheaper at any other recognized licensed mail order pharmacy, we will not only match their price, we will beat it by 25% of the difference. It is our 125% price match guarantee!

Example: If you find a product on Canada Drugs Direct for $50.00 and find the same product for $40.00 at another mail order pharmacy, we will provide you with a $12.50 discount, bringing your total to $37.50.

To get the discount please make sure to mention the price match to the customer service team when they call to collect payment for your order. Or call toll free at 1-888-904-8467 to place the order through the phone.

Terms & Conditions of Program

  • Guaranteed lowest price is only valid at the time of sale.
  • We will only match the current advertised price.
  • Products must be identical and in stock at the time of placing an order with a licensed mail order pharmacy. They must be an online Canadian pharmacy with an address in Canada.
  • Products must be authentic in brand and size (same manufacturer, same country of manufacture, same pack size, same strength and same quantity).
  • Products must be new. We cannot match the price of any used, short expiry or expired product.
  • Price match can only be issued over the phone with our customer service team. Please note at this time we cannot offer price matching for the products Ozempic or Saxenda.
What is a Generic Drug?

A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.

The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.

Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.


Daypro is a non-steroidal anti-inflammatory drug (NSAID) available by prescription to relieve signs and symptoms of osteoarthritis (OA), rheumatoid arthritis (RA), and juvenile rheumatoid arthritis (JRA).

Daypro is available in 600 mg oral caplets.


Daypro should be taken as prescribed by your doctor. Any questions or concerns about the medication may be referred to your doctor or pharmacist.

Dosing for each patient is individualized and depends on treatment goals; however, the lowest effective dose should be used for the shortest duration.

Recommended dosing for OA: Two 600 mg caplets (1200 mg) by mouth once daily

Recommended dosing for RA: Two 600 mg caplets (1200 mg) by mouth once daily

Recommended dosing for JRA:

  • Patients weighing 22-31 kg (48.4-68.2 lbs): One caplet (600 mg) by mouth once daily
  • Patients weighing 32-54 kg (70.4-118.8 lbs): 900 mg by mouth once daily
  • Patients weighing at least 55 kg (121 lbs): Two caplets (1200 mg) by mouth once daily


The active ingredient in Daypro is oxaprozin.

The inactive ingredients in Daypro include microcrystalline cellulose, hypromellose, methylcellulose, magnesium stearate, polacrilin potassium, starch, polyethylene glycol, and titanium dioxide.


Some patients should avoid taking Daypro, including those who:

  • Have an allergy to the medication or any of its ingredients
  • Have a history of asthma, hives, or other allergic-type reactions after taking aspirin or other NSAIDs
  • Are undergoing coronary artery bypass graft (CABG) surgery


  • Daypro contains the following FDA Boxed Warning:
  • The risk of serious cardiovascular thrombotic events such as potentially fatal heart attack and stroke is increased by NSAID use. The risk may occur early in treatment and may increase the longer a patient is on the medication.
  • Patients who are undergoing CABG surgery should not take Daypro.
  • The risk of serious and potentially fatal gastrointestinal (GI) adverse events such as bleeding, ulceration, and perforation of the stomach or intestines, is increased by NSAID use. These events can occur at any time during treatment and may not always have warning symptoms. Those at greater risk include older patients and patients who have had peptic ulcer disease and/or GI bleeding.
  • Before you start taking Daypro medication, tell your doctor about:
    • All the medications you take, including prescription and over-the-counter medications
    • Your allergies
    • Your current health conditions and past medical history
    • Your pregnancy status
    • Your breastfeeding status
  • Liver damage that leads to warning signs and symptoms such as nausea, fatigue, lethargy, diarrhea, itching, right upper quadrant tenderness, flu-like symptoms, and yellowing of the skin or whites of the eyes can occur with Daypro use. If you experience any of these signs and symptoms, seek medical care right away.
  • Blood pressure should be monitored while on Daypro, as the medication can cause high blood pressure, worsen pre-existing high blood pressure, or affect the way some blood pressure medications work.
  • Patients who have severe heart failure or advanced kidney disease should avoid taking Daypro unless the benefits outweigh the risks.
  • Daypro can cause anaphylactic reactions in some people. Immediately seek emergency care if you have difficulty breathing; swelling of the face, lips, tongue, or throat; a rash; or other symptoms of a severe allergic reaction.
  • Patients who have aspirin-sensitive asthma should avoid taking Daypro. Monitoring should, however, still take place in patients with asthma that is not aspirin-sensitive.
  • Daypro can cause serious skin reactions. Quit Daypro use and contact your doctor as soon as you notice a rash or other signs of a reaction.
  • Daypro can cause life-threatening and potentially fatal Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS), which can cause a fever, rash, swollen lymph nodes, and/or facial swelling, liver or kidney inflammation, bleeding issues, heart muscle inflammation, or muscle inflammation. Quit Daypro use and seek emergency care immediately if you develop any of these effects.
  • Women who are about 30 weeks pregnant or later should avoid taking NSAIDs including Daypro because they can injure an unborn fetus.
  • Anemia and an increased risk of bleeding can be caused by NSAIDs including Daypro. Seek medical care immediately if you have symptoms of anemia or bleeding.

Side Effects

Constipation, diarrhea, indigestion, nausea, and rash are common Daypro side effects. These are not all the side effects that can occur, so call your doctor if you develop bothersome or persistent side effects.

You can buy Daypro today at a competitive price!


  1. Daypro. New York, NY: Pfizer Labs; 2022.

IMPORTANT NOTE: The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.

product-reviews Product Reviews