Cytoxan (Cyclophosphamide)

Also Known as procytox

Prescription medicineOnly Available By Prescription
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Strength Pack Size Qty
Strength
50mg
Pack Size
Qty

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We guarantee the lowest price on all of our prescription products. If you find your medications cheaper at any other recognized licensed mail order pharmacy, we will not only match their price, we will beat it by 25% of the difference. It is our 125% price match guarantee!

Example: If you find a product on Canada Drugs Direct for $50.00 and find the same product for $40.00 at another mail order pharmacy, we will provide you with a $12.50 discount, bringing your total to $37.50.

To get the discount please make sure to mention the price match to the customer service team when they call to collect payment for your order. Or call toll free at 1-888-904-8467 to place the order through the phone.

Terms & Conditions of Program

  • Guaranteed lowest price is only valid at the time of sale.
  • We will only match the current advertised price.
  • Products must be identical and in stock at the time of placing an order with a licensed mail order pharmacy. They must be an online Canadian pharmacy with an address in Canada.
  • Products must be authentic in brand and size (same manufacturer, same country of manufacture, same pack size, same strength and same quantity).
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  • Price match can only be issued over the phone with our customer service team. Please note at this time we cannot offer price matching for the products Ozempic or Saxenda.
What is a Generic Drug?

A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.

The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.

Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.

Description

Cytoxan is a chemotherapy infusion used to treat many different types of cancers. It works by cross-linking DNA strands and preventing further replication of cells in the body, including cancerous cells.


Fact Table

Formula

C7H15Cl2N2O2P

License

US DailyMed

Bioavailability

More than 75% (by mouth)

Legal status

Rx-Only

Chemical Name

Cyclophosphamide

Elimination half-life

3 –12 hours

Dosage (Strength)

50mg (Generic)

Pregnancy

Consult Doctor

Brands

Cytoxan

Protein binding

More than 60%

PubChem CID

2907

MedlinePlus

a682080

ChEBI

4027

ATC code

L01AA01

DrugBank

DB00531

KEGG

D07760

Routes of administration

By mouth

Directions

Cytoxan is infused in a blood vessel over time. The dose will be determined by your oncologist and cancer-care team. Follow their instructions carefully.

Ingredients

The active ingredient in this drug is cyclophosphamide.

Interactions

Tell your oncologist about all drugs you are taking, including:

  • Abrocitinib
  • Baricitinib
  • BCG Products
  • Brivudine
  • Cladribine
  • Dengue Tetravalent Vaccine (Live)
  • Deucravacitinib
  • Dipyrone
  • Etanercept
  • Fexinidazole
  • Filgotinib
  • Mumps- Rubella- or Varicella-Containing Live Vaccines
  • Natalizumab
  • Pimecrolimus
  • Poliovirus Vaccine (Live/Trivalent/Oral)
  • Ruxolitinib (Topical)
  • Tacrolimus (Topical)
  • Talimogene Laherparepvec
  • Tertomotide
  • Tofacitinib
  • Typhoid Vaccine
  • Upadacitinib
  • Yellow Fever Vaccine

Cautions

Use caution if you have a history of kidney or liver disease before starting this drug.

Some formulations may contain ethyl alcohol, which can impair driving ability.

Ask your oncologist about precautions that apply to you.

Side Effects

The most common side effects include:

  • Acute myocardial infarction
  • Acute pancreatitis
  • Ageusia
  • Alopecia
  • Amenorrhea
  • Anemia
  • Atrial fibrillation
  • Atrial flutter
  • Azoospermia
  • Bladder carcinoma
  • Bladder disease
  • Bone marrow depression
  • Bradycardia
  • Cardiac tamponade
  • Cardiogenic shock
  • Cardiomyopathy
  • Changes in nails
  • Chest pain
  • Cholestasis
  • Colitis
  • Constipation
  • Cystitis
  • Decreased serum glucose
  • Defective oogenesis
  • Defective spermatogenesis
  • Dermatitis
  • Dysgeusia
  • Edema
  • Enteritis
  • Erythema multiforme
  • Erythema of skin
  • Febrile neutropenia
  • Fluid retention
  • Flushing
  • Gastrointestinal hemorrhage
  • Heart failure
  • Hematuria
  • Hot flash
  • Hyperhidrosis
  • Hypertension
  • Hyponatremia
  • Hypotension
  • Increased lactate dehydrogenase
  • Increased serum glucose
  • Infertility
  • Infrequent uterine bleeding
  • Leukopenia
  • Malignant neoplasm of thyroid
  • Myelodysplastic syndrome
  • Myocarditis
  • Nausea
  • Nephrogenic diabetes insipidus
  • Neutropenia
  • Neutropenic typhlitis
  • Oligospermia
  • Oral mucosa ulcer
  • Palpitations
  • Parotitis
  • Pericardial effusion
  • Pericarditis
  • Peripheral ischemia
  • Premature labor
  • Prolonged QT interval on ECG
  • Pruritus
  • Pulmonary embolism
  • Pulmonary hemorrhage
  • Pyelitis
  • Skin abnormalities related to radiation recall
  • Skin blister
  • Skin rash
  • Skin toxicity
  • Stevens-Johnson syndrome
  • Stomatitis
  • Supraventricular cardiac arrhythmia
  • Tachycardia
  • Testicular atrophy
  • Toxic epidermal necrolysis
  • Toxic nephrosis
  • Ureteral disease
  • Urticaria
  • Vasculitis
  • Venous thrombosis
  • Ventricular arrhythmia
  • Vomiting
  • Water intoxication

References

  1. Cytoxan [package insert]. Columbus, Ohio: Roxane; 2007.

IMPORTANT NOTE: The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.

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