Canada Drugs Direct

Visiting from Canada?

Want to save up to 80% on your medications? Signup below to be notified if we open a Canadian Online Pharmacy.

I agree to receive email updates from Canada Drugs Direct

Looking for Call us toll free 1-800-500-2897

Credelio (Lotilaner)

Prescription medicineOnly Available By Prescription

Top brand choice

Strength Pack Size Qty
112mg XS Dogs (2.5-5kg)
Pack Size
225mg S Dogs (>5.5-11kg)
Pack Size
450mg L Dogs (11-22kg)
Pack Size
900mg XL Dogs (22-45kg)
Pack Size
12mg Chew Tabs For Cat
Pack Size
48mg Chew Tabs For Cat
Pack Size

You'll have option to make 4 interest-free payments by credit card once your order is confirmed using

What if I find a lower price with another pharmacy?

We guarantee the lowest price on all of our prescription products. If you find your medications cheaper at any other recognized licensed mail order pharmacy, we will not only match their price, we will beat it by 25% of the difference. It is our 125% price match guarantee!

Example: If you find a product on Canada Drugs Direct for $50.00 and find the same product for $40.00 at another mail order pharmacy, we will provide you with a $12.50 discount, bringing your total to $37.50.

To get the discount please make sure to mention the price match to the customer service team when they call to collect payment for your order. Or call toll free at 1-888-904-8467 to place the order through the phone.

Terms & Conditions of Program

  • Guaranteed lowest price is only valid at the time of sale.
  • We will only match the current advertised price.
  • Products must be identical and in stock at the time of placing an order with a licensed mail order pharmacy. The must be a member of CIPA (Canadian International Pharmacy Association).
  • Products must be authentic in brand and size (same manufacturer, same country of manufacture, same pack size, same strength and same quantity).
  • Products must be new. We cannot match the price of any used, short expiry or expired product.
  • Price match can only be issued over the phone with our customer service team
What is a Generic Drug?

A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.

The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.

Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.


Credelio (lotilaner) is a medication used to treat and prevent flea infestations and to treat tick infestations in dogs and puppies that are at least 8 weeks old and weigh at least 4.4 pounds; it is prescribed by a licensed veterinarian.


Credelio is available in different strengths; it is a beef-flavored chewable tablet. The dose is dependent upon your dog's weight. Appropriate dosing should be discussed with your veterinarian. Your vet will provide instructions on how to properly administer Credelio to your dog. 

Credelio is given orally one time a month. It should be administered with food or within 30 minutes of feeding your dog. 

Humans should not use Credelio. Children and other pets should be kept away from the medication.


The active ingredient contained in Credelio is lotilaner, an isoxazoline.


Credelio has no known contraindications. 


  • Before administering Credelio to your dog, tell your vet if your dog:
    • Takes any medications
    • Has any allergies
    • Has any medical conditions
    • Is pregnant or nursing
  • Credelio belongs to a class of medications that has been associated with neurological adverse reactions such as tremors, balance and coordination problems, and seizures. Dogs that don't have a history of seizures may experience seizures. Dogs that have a history of seizures or neurological problems should be given Credelio with caution. 

Side Effects

Weight loss, excessive urination, diarrhea, and elevated blood urea nitrogen levels can be caused by Credelio. If your dog develops concerning or persistent side effects, immediately call your vet. 


  1. Credelio (lotilaner). Greenfield, IN: Elanco US Inc.; 2020.

IMPORTANT NOTE: The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.

product-reviews Product Reviews