Cotellic (Cobimetinib)

Prescription medicineOnly Available By Prescription
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20mg
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We guarantee the lowest price on all of our prescription products. If you find your medications cheaper at any other recognized licensed mail order pharmacy, we will not only match their price, we will beat it by 25% of the difference. It is our 125% price match guarantee!

Example: If you find a product on Canada Drugs Direct for $50.00 and find the same product for $40.00 at another mail order pharmacy, we will provide you with a $12.50 discount, bringing your total to $37.50.

To get the discount please make sure to mention the price match to the customer service team when they call to collect payment for your order. Or call toll free at 1-888-904-8467 to place the order through the phone.

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  • Guaranteed lowest price is only valid at the time of sale.
  • We will only match the current advertised price.
  • Products must be identical and in stock at the time of placing an order with a licensed mail order pharmacy. They must be an online Canadian pharmacy with an address in Canada.
  • Products must be authentic in brand and size (same manufacturer, same country of manufacture, same pack size, same strength and same quantity).
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  • Price match can only be issued over the phone with our customer service team. Please note at this time we cannot offer price matching for the products Ozempic or Saxenda.
What is a Generic Drug?

A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.

The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.

Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.

Description

Cotellic (cobimetinib) is a medication prescribed to adults for treating unresectable or metastatic melanoma or histiocytic neoplasms.

Cotellic comes in 20 mg tablets for oral administration.

Directions

Cotellic should be taken as directed by your doctor, who will determine an appropriate Cotellic dosage.

Store Cotellic tablets below 30oC (86oF) and out of reach of children.

Carefully read the information leaflet that accompanies your Cotellic prescription for further instructions for use.

Any questions or concerns you have may be referred to your doctor or pharmacist.

Ingredients

Cobimetinib is the active ingredient in Cotellic.

Microcrystalline cellulose, lactose monohydrate, croscarmellose sodium, magnesium stearate, polyvinyl alcohol, titanium dioxide, polyethylene glycol 3350, and talc are the inactive ingredients included.

Contraindications

Cotellic does not have any contraindications per the most recent Prescribing Information.

Cautions

  • Inform your doctor of the following before you start taking Cotellic:
    • All the medications you take, including prescription and nonprescription medications, vitamins, and supplements
    • Any allergies you have
    • Any current health problems you have
    • Your past medical history
    • If you are pregnant or breastfeeding
  • Cotellic contains the following warnings and precautions:
    • New cancer development
    • Bleeding that is major
    • Heart muscle disease
    • Skin rashes that are severe
    • Retinopathy, retinal vein occlusion, or other eye problems
    • Liver issues
    • Muscle tissue breakdown that leads to the release of substances in the blood that can cause damage to the kidneys
    • Photosensitivity that is severe; therefore, it is recommended that you avoid exposure to the sun
    • Fetal harm; females of reproductive potential should be advised to use effective contraception while being treated with Cotellic and for 2 weeks after taking the last dose of treatment
    • Breastfeeding should be avoided

Side Effects

Cotellic side effects in patients with unresectable or metastatic melanoma include but are not limited to diarrhea, photosensitivity, nausea, fever, vomiting, abnormal labs (increased GGT, CPK, and liver enzymes and decreased phosphorus, sodium, and lymphocytes).

Cotellic side effects in patients with histiocytic neoplasms include but are not limited to acne, skin conditions, diarrhea, infection, fatigue, nausea, swelling, dry skin, skin rash, itching, indigestion, vomiting, shortness of breath, urinary tract infections, anemia, and abnormal labs (decreased sodium, potassium, calcium, lymphocytes, and leukocytes and increased CPK, creatinine, and liver enzymes).

Contact your doctor right away if you have bothersome or persistent side effects.

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References

  1. Cotellic. South San Francisco, CA: Genentech USA, Inc.; 2023.
  2. Rhabdomyolysis. Cleveland Clinic; Last reviewed February 24, 2023.



IMPORTANT NOTE: The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.

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