Coreg CR (Carvedilol ER)

Prescription medicineOnly Available By Prescription

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What if I find a lower price with another pharmacy?

We guarantee the lowest price on all of our prescription products. If you find your medications cheaper at any other recognized licensed mail order pharmacy, we will not only match their price, we will beat it by 25% of the difference. It is our 125% price match guarantee!

Example: If you find a product on Canada Drugs Direct for $50.00 and find the same product for $40.00 at another mail order pharmacy, we will provide you with a $12.50 discount, bringing your total to $37.50.

To get the discount please make sure to mention the price match to the customer service team when they call to collect payment for your order. Or call toll free at 1-888-904-8467 to place the order through the phone.

Terms & Conditions of Program

  • Guaranteed lowest price is only valid at the time of sale.
  • We will only match the current advertised price.
  • Products must be identical and in stock at the time of placing an order with a licensed mail order pharmacy. They must be an online Canadian pharmacy with an address in Canada.
  • Products must be authentic in brand and size (same manufacturer, same country of manufacture, same pack size, same strength and same quantity).
  • Products must be new. We cannot match the price of any used, short expiry or expired product.
  • Price match can only be issued over the phone with our customer service team. Please note at this time we cannot offer price matching for the products Ozempic or Saxenda.
What is a Generic Drug?

A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.

The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.

Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.


Coreg CR is used to treat heart failure and high blood pressure. In addition, it's used to reduce cardiovascular death in clinically stable patients who've had a heart attack and have a left ventricular ejection fraction equal to 40% or less.

Coreg CR comes in 10 mg, 20 mg, 40 mg, and 80 mg oral capsules.

Carvedilol phosphate extended-release is the generic for Coreg CR.

Fact Table




US DailyMed



Legal status


Chemical Name


Elimination half-life

7–10 hours

Dosage (Strength)

10mg, 20mg, 40mg, 80mg


Consult Doctor



Protein binding


PubChem CID






ATC code






Routes of administration

By mouth


Carefully read the information that comes with your Coreg CR prescription. Take Coreg CR as prescribed by your doctor. If you have any questions or concerns about the medication, talk to your doctor or pharmacist. Do not abruptly stop taking Coreg CR; doing so can worsen chest pain or cause a heart attack or abnormal heart rhythms.

Because Coreg CR is designed to stay in the body longer, it's recommended to be taken once daily in the morning with food. Each patient's dose is based on the condition being treated, their health history, and their current health problems. 

Swallow the capsules whole; do not crush or chew them. 

However, swallowing capsules can be a challenge for some patients. Therefore, the capsules may be opened and the contents sprinkled over a spoonful of applesauce and consumed right away.


The active ingredient in Coreg CR is carvedilol phosphate, a beta-adrenergic blocking agent with alpha-1 blocking properties.


Coreg CR may not be the best treatment option for everyone. 

Do not take Coreg CR if you have any of the following conditions:

  • Bronchial asthma or other related conditions
  • Second- or third-degree AV block
  • Sick sinus syndrome
  • Severely low heart rate without a permanent pacemaker
  • Cardiogenic shock or decompensated heart failure that requires IV inotropic therapy
  • Severe liver problems
  • A previous allergy or reaction to Coreg CR or any of its components


Before you begin treatment with Coreg CR, inform your doctor of:

  • All the medications you take, including prescription and nonprescription
  • Your allergies
  • Your medical history and health problems
  • Your pregnancy or breastfeeding status
  • Coreg CR helps treat high blood pressure by lessening the stress on your heart and blood vessels. Because it can cause low blood pressure, caution should be used when standing from a sitting position. Do not drive or participate in other hazardous activities until you know how Coreg CR affects you.
  • Upon increasing the dose of Coreg CR, heart failure or fluid retention may worsen. Call your doctor right away if you have swelling, difficulty breathing, or rapid weight gain.
  • The symptoms of low blood sugar, including rapid heart rate, may be masked by Coreg CR. Patients with diabetes should monitor their blood sugar regularly and treat low blood sugar as instructed by their doctor.
  • The symptoms of slowed or stopped blood flow through the arteries in patients with peripheral vascular disease may worsen with the use of Coreg CR. Caution should be used in these patients.
  • Kidney function may worsen with the use of Coreg CR, especially in patients with low blood pressure, ischemic heart disease, diffuse vascular disease, and/or underlying kidney problems.
  • Patients should use caution before undergoing major surgery.
  • The signs of overactive thyroid, or hyperthyroidism, may be masked by Coreg CR. In addition, the symptoms of hyperthyroidism may worsen or a thyroid storm may occur if Coreg CR is stopped abruptly.
  • Caution should be used in patients who take Coreg CR and are suspected to have pheochromocytoma.
  • Caution should be used in patients who take Coreg CR and are suspected to have Prinzmetal's variant angina.
  • Coreg CR has alpha-blocking capabilities, which can cause Intraoperative Floppy Iris Syndrome during cataract surgery.
  • Severe allergic reactions, including difficulty breathing; swelling of the lips, throat, and tongue; and rash can occur with Coreg CR. Seek emergency care immediately if you have any of these effects.

Side Effects

Common Coreg CR side effects include weakness, fatigue, low heart rate, low blood pressure, headache, and dizziness; however, these are not all the side effects that can occur. 

Call your doctor immediately if you have bothersome or persistent side effects.


  1. Coreg CR-carvedilol phosphate capsule, extended release. GlaxoSmithKline LLC; 2020.

IMPORTANT NOTE: The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.

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