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Compazine (Prochlorperazine)

Prescription medicineOnly Available By Prescription

Top Generic choice

Strength Pack Size Qty
Pack Size
Pack Size

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What if I find a lower price with another pharmacy?

We guarantee the lowest price on all of our prescription products. If you find your medications cheaper at any other recognized licensed mail order pharmacy, we will not only match their price, we will beat it by 25% of the difference. It is our 125% price match guarantee!

Example: If you find a product on Canada Drugs Direct for $50.00 and find the same product for $40.00 at another mail order pharmacy, we will provide you with a $12.50 discount, bringing your total to $37.50.

To get the discount please make sure to mention the price match to the customer service team when they call to collect payment for your order. Or call toll free at 1-888-904-8467 to place the order through the phone.

Terms & Conditions of Program

  • Guaranteed lowest price is only valid at the time of sale.
  • We will only match the current advertised price.
  • Products must be identical and in stock at the time of placing an order with a licensed mail order pharmacy. They must be an online Canadian pharmacy with an address in Canada.
  • Products must be authentic in brand and size (same manufacturer, same country of manufacture, same pack size, same strength and same quantity).
  • Products must be new. We cannot match the price of any used, short expiry or expired product.
  • Price match can only be issued over the phone with our customer service team. Please note at this time we cannot offer price matching for the products Ozempic or Saxenda.
What is a Generic Drug?

A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.

The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.

Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.


Your healthcare provider may prescribe Compazine to treat nausea and vomiting when other treatments have failed. 

Compazine belongs to a group of medications called antipsychotics, but it is no longer used for the treatment of psychotic disorders. Compazine blocks dopamine receptors in the brain, which are what cause feelings of nausea and vomiting. By blocking these receptors, Compazine helps to relieve symptoms.

Fact Table






Unknown, but presumed substantial

Legal status


Chemical Name


Elimination half-life

4–8 hours

Dosage (Strength)



Consult Doctor


Compazine, Stemetil

Protein binding


PubChem CID






ATC code






Routes of administration

By mouth


Take Compazine exactly as directed by your healthcare provider. 

The normal dose of Compazine is 5-10 mg by mouth every 3-4 hours as needed. Do not take more than 40 mg of Compazine in 24 hours.


The name for Compazine generic and the active ingredient in Compazine is prochlorperazine.


Common drug-drug interactions with Compazine may include:

  • Aclidinium
  • Azelastine
  • Bromperidol
  • Buprenorphine
  • Cabergoline
  • Clozapine
  • Dofetilide
  • Dopamine agonists
  • Flunitrazepam
  • Glycopyrrolate
  • Iohexol
  • Ipratropium
  • Metoclopramide
  • Opioid agonists
  • Orphenadrine
  • Oxybate salt products
  • Potassium chloride
  • Pramlintide
  • Saquinavir
  • Suvorexant
  • Thalidomide
  • Tiotropium
  • Umeclidinium
  • Zolpidem

Tell your doctor and pharmacist about all of the medications you are taking before starting Compazine. 


Older adults with dementia-related psychosis are at an increased risk of death if they take antipsychotics, including Compazine. 

Tell your doctor if you have any heart conditions before taking Compazine. 

Compazine can affect your ability to drive. Do not drive a vehicle until you know how it affects you.

Use caution if you have a history of kidney or liver problems. 

Ask your doctor or pharmacist for a full list of precautions.

Side Effects

The most common side effects when taking Compazine can include:

  • Agranulocytosis
  • Amenorrhea
  • Blurred vision
  • Dizziness
  • Drowsiness
  • Extrapyramidal reactions
  • Hypotension
  • Leukopenia
  • Neuroleptic malignant syndrome (NMS)
  • Skin reactions


Compazine [package insert]. Research Triangle Park, NC: GlaxoSmithKline; 2004.

IMPORTANT NOTE: The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.

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