Comfortis Chewable Tablets (Spinosad)

Prescription medicineOnly Available By Prescription

What if I find a lower price with another pharmacy?

We guarantee the lowest price on all of our prescription products. If you find your medications cheaper at any other recognized licensed mail order pharmacy, we will not only match their price, we will beat it by 25% of the difference. It is our 125% price match guarantee!

Example: If you find a product on Canada Drugs Direct for $50.00 and find the same product for $40.00 at another mail order pharmacy, we will provide you with a $12.50 discount, bringing your total to $37.50.

To get the discount please make sure to mention the price match to the customer service team when they call to collect payment for your order. Or call toll free at 1-888-904-8467 to place the order through the phone.

Terms & Conditions of Program

  • Guaranteed lowest price is only valid at the time of sale.
  • We will only match the current advertised price.
  • Products must be identical and in stock at the time of placing an order with a licensed mail order pharmacy. They must be an online Canadian pharmacy with an address in Canada.
  • Products must be authentic in brand and size (same manufacturer, same country of manufacture, same pack size, same strength and same quantity).
  • Products must be new. We cannot match the price of any used, short expiry or expired product.
  • Price match can only be issued over the phone with our customer service team. Please note at this time we cannot offer price matching for the products Ozempic or Saxenda.
What is a Generic Drug?

A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.

The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.

Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.


Comfortis chewable tablets kill fleas and are indicated for the prevention and treatment of flea infestations on Dogs and now also Cats for one month.

Note: The UK doses Comfortis at a higher level than the U.S. therefore the weight in kg indicated on the UK sourced packs will be less than the actual weight when converted to lbs. Simply choose the appropriate Pack Size by your Pet's weight in LBS. and the correct RECOMMENDED U.S. MIN. DOSAGE of Spinosad will be shipped. Upon receipt, verify dosage (mg) indicated on Pack matches the recommended U.S. dosage (mg) for your Pet's weight in LBS.

DOG: Weight (lbs) DOG: Weight (kg) Indicated on Pack CAT: Weight (lbs) Spinosad (mg) Sourced from UK
5 - 10lbs 2.3 - 4.5kg 4.1 - 6lbs 140
10.1 - 20lbs 3.9 - 6kg 6.1 - 12lbs 270 YES
20.1 - 40lbs 9.1 - 18kg 12.1 - 24lbs 560
40.1 - 60lbs 18.1 - 27kg 810
60.1 - 120lbs 23.2 - 36kg 1620 YES

Dogs: Recommended U.S. Minimum Dosage is 13.5mg/lb per month
Cats: Recommended U.S. Minimum dosage is 22.5mg/lb per month


Comfortis chewable tablets should be given with food for maximum effectiveness. They are readily consumed when offered by hand prior to feeding but may also be given in food or by placing the tablet at the back of the tongue and encouraging the animal to swallow.
Treatment with Comfortis chewable tablets may begin at any time of the year, but should preferably begin one month before fleas become active and continue until the end of the flea season. In areas where fleas are common year-round, continue treatment with Comfortis throughout the year. In order to minimize the likelihood of flea reinfestation, all animals within a household should be treated with an approved flea protection product. DOGS: Minimum Dosage is 13.5mg/lb- Monthly 14 Weeks or older & 3.3lbs or greater Dogs over 120 lbs should be administered the appropriate combination

CATS: Minimum dosage is 22.5mg/lb -Monthly 14 Weeks or older & 2lbs. or greater Cats over 24lbs should be administered the appropriate combination




Comfortis should be used with caution in breeding females, however the safe use of this product has not been studied in breeding males. Comfortis should also be used with caution in dogs with pre-existing epilepsy.
Vomiting has been seen on rare occasions in association with the administration of Comfortis. If vomiting occurs within an hour of administration, it is recommended that the animal is redosed with another full dose of the medication.
On rare occasions, a reduced appetite, lethargy, diarrhea, a cough, increased drinking, reddened skin, salivation, hyperactivity, an increased appetite and vocalization have been seen in treated animals, most commonly in association with overdosing of the medication.
Comfortis chewable tablets have been safely administered in conjunction with other frequently used veterinary products, such as vaccines, anthelmintics, antibiotics, steroids, flea and tick control products, anesthetics, NSAIDs, antihistamines, alternative/herbal remedies, shampoos, and prescription diets.
Not for human use. Keep this and all drugs out of the reach of children.

Side Effects

IMPORTANT NOTE: The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for your pet. See your veterinarian for medical advice and treatment for your pet if you have any concerns.

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