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Combivir (Lamivudine/Zidovudine)

Prescription medicineOnly Available By Prescription

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What if I find a lower price with another pharmacy?

We guarantee the lowest price on all of our prescription products. If you find your medications cheaper at any other recognized licensed mail order pharmacy, we will not only match their price, we will beat it by 25% of the difference. It is our 125% price match guarantee!

Example: If you find a product on Canada Drugs Direct for $50.00 and find the same product for $40.00 at another mail order pharmacy, we will provide you with a $12.50 discount, bringing your total to $37.50.

To get the discount please make sure to mention the price match to the customer service team when they call to collect payment for your order. Or call toll free at 1-888-904-8467 to place the order through the phone.

Terms & Conditions of Program

  • Guaranteed lowest price is only valid at the time of sale.
  • We will only match the current advertised price.
  • Products must be identical and in stock at the time of placing an order with a licensed mail order pharmacy. They must be an online Canadian pharmacy with an address in Canada.
  • Products must be authentic in brand and size (same manufacturer, same country of manufacture, same pack size, same strength and same quantity).
  • Products must be new. We cannot match the price of any used, short expiry or expired product.
  • Price match can only be issued over the phone with our customer service team. Please note at this time we cannot offer price matching for the products Ozempic or Saxenda.
What is a Generic Drug?

A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.

The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.

Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.


Combivir is a prescription medication that is used to treat HIV-1 infection. It is available in an oral tablet containing two nucleoside analogue reverse transcriptase inhibitors: lamivudine and zidovudine.

Lamivudine and zidovudine are Combivir generic.


Take Combivir as your doctor has instructed. Discuss any questions or concerns about the medication with your doctor or pharmacist.

Adults, adolescents, and pediatrics who weigh 30 kg or more are recommended to take one tablet by mouth twice daily.


Combivir tablets contain 150 mg of lamivudine and 300 mg of zidovudine. Colloidal silicon dioxide, hypromellose, magnesium stearate, microcrystalline cellulose, polyethylene glycol, polysorbate 80, sodium starch glycolate, and titanium dioxide are the inactive ingredients included.


Patients who are allergic to lamivudine or zidovudine should avoid Combivir.


Combivir is associated with the following FDA Boxed Warnings:

  • Neutropenia, anemia, or any other hematologic toxicity can occur with the use of zidovudine, an active ingredient in Combivir.
  • Taking zidovudine for a long period of time can cause symptomatic myopathy.
  • Combivir is associated with lactic acidosis and severe liver enlargement with steatosis.
  • Stopping lamivudine, an active ingredient in Combivir, can worsen hepatitis B in patients with hepatitis B and HIV-1. Close monitoring of liver function should be done in these patients and anti-hepatitis B treatment started as necessary.
  • Before you begin taking Combivir, it’s important that you discuss the following with your doctor:
    • All the medications you take
    • Your allergies
    • Your medical problems and health history
    • If you are pregnant or breastfeeding
  • Patients should avoid taking Combivir with other medications that contain lamivudine, zidovudine, or emtricitabine.
  • Patients with HIV-1 and hepatitis C virus (HCV) and are receiving combination antiretroviral therapy and interferon alfa with or without ribavirin may develop liver problems.
  • HIV-1 patients with HCV may develop worsening anemia when taking ribavirin with zidovudine; therefore, this drug combination is not recommended in these patients.
  • Combivir may cause pancreatitis.
  • Combivir may cause immune system problems.
  • Combivir may cause accumulation of body fat.

Side Effects

Common Combivir side effects include headache, nausea, general discomfort, fatigue, diarrhea, cough, and nasal symptoms. Patients may experience other side effects as well. Contact your doctor immediately if you have side effects that bother you or won’t go away.

With a valid prescription from your doctor, you can buy Combivir 150 mg/300 mg tablets online at a competitive price at Canada Drugs Direct.


Combivir. Research Triangle Park, NC: GlaxoSmithKline; 2015.

IMPORTANT NOTE: The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.

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