Combivent Respimat Inhaler (Ipratropium / Albuterol)

Prescription medicineOnly Available By Prescription

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Strength Pack Size Qty
20/100mcg (120 doses/inhaler)
Pack Size

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What is a Generic Drug?

A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.

The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.

Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.


Combivent Respimat is an inhalation spray that contains an anticholinergic, ipratropium bromide, and a beta2-adrenergic agonist, albuterol sulfate. It's used to treat chronic obstructive pulmonary disease (COPD) in patients who need a second medication to help relax and open up their airways to help them breathe easier.

Combivent Respimat is supplied as an inhaler. Each inhalation delivers 20 mcg of ipratropium bromide and 100 mcg of albuterol.

Fact Table




US DailyMed


2% and 7 to 28%

Legal status


Chemical Name

Ipratropium bromide/salbutamol

Elimination half-life

2 hours

Dosage (Strength)

20/100 mcg (120 doses/inhaler)


Consult Doctor


Combivent Respimat

Protein binding

Less than 20%

PubChem CID






ATC code






Routes of administration



The instructions that come with your Combivent Respimat prescription should be carefully read and followed. Use Combivent Respimat as your doctor has prescribed. Talk to your doctor or pharmacist if you have any questions or concerns. 

The typical dose is to inhale one spray by mouth four times a day. Do not exceed six inhalations within a day.


The active ingredients contained in Combivent Respimat are ipratropium bromide and albuterol sulfate.


Avoid using Combivent Respimat if you have an allergy to any of its ingredients.

Avoid using Combivent Respimat if you have an allergy to atropine or any of its derivatives.


  • Before you start treatment with Combivent Respimat, inform your doctor of:
    • All the medications you use
    • Your allergies
    • Your medical history and health problems
    • Your pregnancy or breastfeeding status
  • Airway constriction that can be life threatening can occur with the use of Combivent Respimat. Seek emergency care right away if this occurs.
  • Serious cardiovascular effects such as high blood pressure, heart attack, rapid heart rate, and other heart arrhythmias can occur with the use of beta2-adrenergic agonists, which is a component of Combivent Respimat. Patients with cardiovascular system disorders should use Combivent Respimat with caution. 
  • Increased pressure in the eyes can occur with the use of ipratropium bromide, a component of Combivent Respimat. Patients with glaucoma should use the medication with caution.
  • Urinary retention can occur with the use of ipratropium bromide, a component of Combivent Respimat. Patients with prostate problems or bladder-neck obstructions should use the medication with caution.
  • Severe allergic reactions can occur with the use of Combivent Respimat. Seek emergency care right away if you have breathing problems, swelling of the face, lips, or tongue, or skin reactions.
  • Patients who have seizures, high thyroid levels, diabetes, and patients who are sensitive to sympathomimetic amines should use Combivent Respimat with caution.
  • Low potassium levels in the blood can occur with the use of beta2-adrenergic agonists, which is a component of Combivent Respimat.

Side Effects

Cough, shortness of breath, headache, bronchitis, nasopharyngitis, and upper respiratory tract infections are some Combivent Respimat side effects; however, these are not all the side effects that can occur.

Call your doctor immediately if you have side effects that bother you or won't go away.


  1. Combivent Respimat (ipratropium bromide and albuterol inhalation spray), for oral inhalation use. Ridgefield, CT: Boehringer Ingelheim Pharmaceuticals, Inc.; 2021.

Frequently Asked Questions about Combivent Respimat Inhaler (Ipratropium / Albuterol)

What's Combivent Respimat used for?

Combivent Respimat helps with ongoing lung problems like wheezing and shortness of breath from COPD, which includes bronchitis and emphysema. It has ipratropium and albuterol to relax muscles around the airways for easier breathing.

How to use Combivent Respimat inhaler?

Use Combivent Respimat 4 times a day, as directed by your doctor. Don't exceed 6 inhalations in 24 hours to avoid risks. Stick to the prescribed dose.

How often can you use Combivent inhaler?

Usually 4 times a day, but you can take more if needed, up to 6 inhalations in 24 hours.

Is Combivent a steroid?

No, it's not. Combivent has ipratropium and albuterol, which help open up your airways but aren't steroids.

Who shouldn't take Combivent?

Avoid it if you're allergic to albuterol, ipratropium, or atropine. If you have heart disease, high blood pressure, epilepsy, diabetes, glaucoma, or kidney issues, talk to your doctor first.

How long can you use Combivent Respimat?

Use it 4 times daily, and one inhaler lasts 30 days with 120 puffs at 1 puff four times a day.

How long does it take for Combivent to work?

Many people feel it working within 15 minutes.

What are the benefits of Combivent?

It helps relax muscles in your airways, making breathing easier. Managing breathing problems can reduce missed work or school time.

What happens if you take too much Combivent?

Overuse may raise the risk of death. If your breathing worsens suddenly (paradoxical bronchospasm), stop using it and seek help immediately.

Is Combivent similar to Symbicort?

They both treat COPD, but Combivent and Symbicort have different ingredients. Combivent has ipratropium and albuterol, while Symbicort combines a corticosteroid with a long-acting bronchodilator.

IMPORTANT NOTE: The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.

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