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Colofac (Mebeverine)

Prescription medicineOnly Available By Prescription

Top Generic choice

Strength Pack Size Qty
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What if I find a lower price with another pharmacy?

We guarantee the lowest price on all of our prescription products. If you find your medications cheaper at any other recognized licensed mail order pharmacy, we will not only match their price, we will beat it by 25% of the difference. It is our 125% price match guarantee!

Example: If you find a product on Canada Drugs Direct for $50.00 and find the same product for $40.00 at another mail order pharmacy, we will provide you with a $12.50 discount, bringing your total to $37.50.

To get the discount please make sure to mention the price match to the customer service team when they call to collect payment for your order. Or call toll free at 1-888-904-8467 to place the order through the phone.

Terms & Conditions of Program

  • Guaranteed lowest price is only valid at the time of sale.
  • We will only match the current advertised price.
  • Products must be identical and in stock at the time of placing an order with a licensed mail order pharmacy. The must be a member of CIPA (Canadian International Pharmacy Association).
  • Products must be authentic in brand and size (same manufacturer, same country of manufacture, same pack size, same strength and same quantity).
  • Products must be new. We cannot match the price of any used, short expiry or expired product.
  • Price match can only be issued over the phone with our customer service team
What is a Generic Drug?

A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.

The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.

Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.


Colofac (Mebeverine) is an antispasmodic medicine used to alleviate symptoms related to irritable bowel syndrome (IBS) and intestinal spasms. It works by targeting specific muscles in the walls of the intestines, causing them to relax and easing pain and bloating in the lower abdomen. Classified as an antispasmodic, this medication is commonly taken to treat stomach cramps, diarrhea, and gas associated with IBS and similar conditions.

Fact Table







Legal status


Chemical Name


Elimination half-life

2 hours

Dosage (Strength)



Consult Doctor



Protein binding


PubChem CID



Not Assigned


Not Assigned

ATC code






Routes of administration

By mouth


The standard dosage for Colofac tablets is 135 mg, and it is recommended to take the doses about 20 minutes before your three main meals of the day. This timing helps to maximize the effectiveness of the medication in controlling muscle spasms and stomach cramps during mealtime.

To use Colofac effectively, swallow the tablets whole with a small glass of water. Do not chew the tablets, as they may have an unpleasant taste.


Colofac contains Mebeverine as the active ingredient.


Avoid taking or using this medication if you have a known or suspected hypersensitivity to Mebeverine or any of the ingredients in the medication.


  • If you plan to take Mebeverine, consider discussing with your doctor:
    • Other medications you are taking, including over-the-counter and prescription drugs
    • Existing medical conditions
    • If you are pregnant or breastfeeding
  • Individuals with cardiac dysrhythmia, atrioventricular heart block, angina, or severe ischaemic heart disease may need to use Colofac with caution.
  • Be mindful if you have symptoms of irritable bowel syndrome that might actually be due to lactose intolerance; Colofac tablets contain lactose.
  • Mebeverine coated tablets contain lactose and sucrose, which may cause issues for patients with certain hereditary problems. These problems may include galactose intolerance, Lapp lactase deficiency, glucose-galactose malabsorption, fructose intolerance, and sucrase-isomaltase insufficiency.
  • If you're living with kidney or liver problems, consult your healthcare provider before starting Colofac, as these conditions could influence how the drug is metabolized.

Side Effects

Colofac may cause side effects, although they are generally mild and often pass quickly. Some common side effects include heartburn, constipation, indigestion, dizziness, insomnia, rash, and headache.

In rare cases, Colofac may cause more serious side effects that require medical attention. If you or someone you know is taking Mebeverine and experiences signs of an allergic reaction, such as hives, severe rash, trouble breathing, swelling of the face or throat, seek medical help immediately.


  1. Colofac 135 mg Tablets Summary of Product Characteristics. Hertfordshire, UK: Mylan; 2016
  2. Colofac (Mebeverine) Package Leaflet. Hertfordshire, UK: Mylan; 2016
  3. Colofac (Mebeverine) Data Sheet. Ellerslie, NZ: Viatris; 2022

IMPORTANT NOTE: The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.

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