Clavulin

Prescription medicineOnly Available By Prescription

What if I find a lower price with another pharmacy?

We guarantee the lowest price on all of our prescription products. If you find your medications cheaper at any other recognized licensed mail order pharmacy, we will not only match their price, we will beat it by 25% of the difference. It is our 125% price match guarantee!

Example: If you find a product on Canada Drugs Direct for $50.00 and find the same product for $40.00 at another mail order pharmacy, we will provide you with a $12.50 discount, bringing your total to $37.50.

To get the discount please make sure to mention the price match to the customer service team when they call to collect payment for your order. Or call toll free at 1-888-904-8467 to place the order through the phone.

Terms & Conditions of Program

  • Guaranteed lowest price is only valid at the time of sale.
  • We will only match the current advertised price.
  • Products must be identical and in stock at the time of placing an order with a licensed mail order pharmacy. They must be an online Canadian pharmacy with an address in Canada.
  • Products must be authentic in brand and size (same manufacturer, same country of manufacture, same pack size, same strength and same quantity).
  • Products must be new. We cannot match the price of any used, short expiry or expired product.
  • Price match can only be issued over the phone with our customer service team. Please note at this time we cannot offer price matching for the products Ozempic or Saxenda.
What is a Generic Drug?

A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.

The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.

Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.

Description

Clavulin is a combination antibiotic containing amoxicillin, a penicillin-type beta-lactam antibiotic, and clavulanic acid, a beta-lactamase inhibitor. It is used to treat a variety of bacterial infections by extending the spectrum of amoxicillin to include beta-lactamase-producing organisms. Clavulin is effective against respiratory tract infections, urinary tract infections, skin and soft tissue infections, and certain dental infections. The clavulanic acid component protects amoxicillin from degradation by beta-lactamase enzymes, restoring its efficacy against resistant bacterial strains.

Fact Table

Formula

C16H19N3O5S (amoxicillin) + C8H9NO5 (clavulanic acid)

License

US FDA / Health Canada

Bioavailability

Amoxicillin: ~95%; Clavulanic acid: ~60% (oral)

Legal status

Prescription only

Chemical Name

Amoxicillin and Clavulanic Acid

Elimination half-life

Amoxicillin: 1–1.5 h; Clavulanic acid: ~1 h

Dosage (Strength)

250/125 mg, 500/125 mg, 875/125 mg tablets; oral suspension available

Pregnancy

Category B – No evidence of risk in humans

Brands

Clavulin, Augmentin, Co-amoxiclav, Curam, others

Protein binding

Amoxicillin: ~20%; Clavulanic acid: ~25%

PubChem CID

Amoxicillin: 33613; Clavulanic acid: 5280980

MedlinePlus

a685024

ChEBI

Amoxicillin: 2676; Clavulanic acid: 37531

ATC code

J01CR02

DrugBank

Amoxicillin: DB01060; Clavulanic acid: DB00766

KEGG

Amoxicillin: D07452; Clavulanic acid: D00210

Routes of administration

Oral, Intravenous

Directions

Clavulin should be administered orally and is available in various formulations, including tablets, chewable tablets, and oral suspensions. Dosing depends on the severity and type of infection, as well as patient age and renal function. It is typically taken every 8 or 12 hours with food to minimize gastrointestinal upset. The tablet should be swallowed whole, and suspensions must be shaken well before use. Always follow the prescribing physician’s instructions precisely.

Ingredients

Active ingredients:

  • Amoxicillin (as amoxicillin trihydrate)
  • Clavulanic acid (as potassium clavulanate)

Inactive ingredients vary by formulation but may include: microcrystalline cellulose, magnesium stearate, colloidal silicon dioxide, sodium starch glycolate, and flavoring agents in suspensions.

Contraindications

Clavulin is contraindicated in patients with:

  • A history of hypersensitivity to amoxicillin, clavulanic acid, other beta-lactam antibiotics (penicillins or cephalosporins)
  • A previous history of cholestatic jaundice or hepatic dysfunction associated with Clavulin or any of its components

Cautions

Use with caution in patients with hepatic impairment; monitor liver function tests during prolonged therapy. In patients with renal impairment, dosage adjustments are necessary. Severe allergic reactions, including anaphylaxis, have been reported. Clavulin should be discontinued if a skin rash or other signs of hypersensitivity appear. Pseudomembranous colitis has been reported with nearly all antibacterial agents, including Clavulin; evaluate patients presenting with diarrhea during or after treatment.

Side Effects

Common side effects may include:

  • Diarrhea
  • Nausea
  • Vomiting
  • Rash
  • Abdominal discomfort
  • Headache
  • Oral or vaginal candidiasis

Serious adverse effects may include hepatic dysfunction (elevated liver enzymes, hepatitis, cholestatic jaundice), severe allergic reactions, and Clostridioides difficile-associated diarrhea.

IMPORTANT NOTE: The information provided above is for general awareness and educational purposes only. It is not intended to diagnose, treat, or replace professional medical or veterinary advice. Always consult your physician, pharmacist, or veterinarian regarding the safety, suitability, and proper use of any medication for yourself or your pet.

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