Only Available By Prescription
Top Generic choice
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25mg
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50mg
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100mg
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200mg
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We guarantee the lowest price on all of our prescription products. If you find your medications cheaper at any other recognized licensed mail order pharmacy, we will not only match their price, we will beat it by 25% of the difference. It is our 125% price match guarantee!
Example: If you find a product on Canada Drugs Direct for $50.00 and find the same product for $40.00 at another mail order pharmacy, we will provide you with a $12.50 discount, bringing your total to $37.50.
To get the discount please make sure to mention the price match to the customer service team when they call to collect payment for your order. Or call toll free at 1-888-904-8467 to place the order through the phone.
Terms & Conditions of Program
A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.
The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.
Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.
Largactil is a medicine used to help people with certain mental health problems. It helps manage conditions like schizophrenia, bipolar disorder, and severe behavioral problems. Largactil can also be used to treat nausea, vomiting, and prolonged hiccups. It works by changing the way chemicals in the brain send messages, which can help improve mood, behavior, and other symptoms.
| Fact Table | |
| Formula | C17H19ClN2S |
| License | US FDA, EMA, WHO |
| Bioavailability | ~30–50% (oral) |
| Legal status | Rx-only |
| Chemical Name | 2-Chloro-10-(3-dimethylaminopropyl)phenothiazine |
| Elimination half-life | 16–30 hours (variable) |
| Dosage (Strength) | 10 mg, 25 mg, 50 mg, 100 mg, 200 mg tablets; oral syrup; 25–50 mg/mL injectable |
| Pregnancy | Category C – Caution advised |
| Brands | Largactil, Thorazine (US), Promapar, Hibernal |
| Protein binding | 90–99% |
| PubChem CID | 2726 |
| MedlinePlus | a682040 |
| ChEBI | 3648 |
| ATC code | N05AA01 |
| DrugBank | DB00477 |
| KEGG | D00271 |
| Routes of administration | Oral, Intramuscular, Intravenous, Rectal |
Largactil is typically taken by mouth as tablets. The amount you need and how often you take it will depend on your condition and other medicines you may be using—always follow the instructions from your doctor or pharmacist. Take your dose at the same time each day for the best results, and do not stop taking it unless your doctor tells you to, even if you start to feel better. Swallow tablets whole with water. If you miss a dose, just take the next one as usual; do not double up. If you are unsure about anything, or if you have trouble remembering your medicine, speak to your doctor or pharmacist for advice.
Chlorpromazine is the active ingredient in Largactil.
Avoid taking or using this medication if any of the following apply:
History of allergic reaction to Largactil or any listed ingredients
Previous allergic reaction to any phenothiazine (e.g., swelling of face, lips, tongue, throat, hands, or feet; difficulty breathing)
Circulatory problems
Blood disorders or bone marrow problems
High blood pressure
Liver problems
Depression of the central nervous system
Phaeochromocytoma (adrenal gland tumor)
Damaged or tampered packaging
Abnormal appearance of tablet, syrup, or ampoule
Before using Largactil, you may want to consult a healthcare provider about the following:
Any existing health conditions
Any allergies
A list of all medications you are currently taking
Whether you are pregnant or breastfeeding
Before taking Largactil, tell your doctor if you have any other health problems like asthma, heart disease, diabetes, epilepsy, prostate issues, glaucoma, or kidney or liver disease. Largactil can affect how these conditions are managed or may cause side effects that make them worse.
Largactil can interact with many medications, including antidepressants, antipsychotics, blood pressure drugs, antibiotics, and seizure medications. This can affect how well your medicines work or cause harmful side effects. Always tell your doctor or pharmacist about everything you're taking, even vitamins or supplements.
Drinking alcohol while on Largactil may make you feel more drowsy or dizzy. The medication can also make your skin more sensitive to sunlight, increasing the risk of sunburn. Avoid tanning beds and use sunscreen and protective clothing if you're going outdoors.
In some cases, Largactil may cause involuntary movements, especially in the face, mouth, or limbs. This side effect, called tardive dyskinesia, may become permanent with long-term use, especially in older adults. Let your doctor know right away if you notice any unusual body movements.
Largactil may cause dizziness, blurred vision, or sleepiness. Avoid driving or using machinery until you know how it affects you. Getting up slowly from sitting or lying down can help prevent light-headedness.
The most common side effects of Largactil include drowsiness, dizziness, dry mouth, constipation, blurred vision, and weight gain. Some people may also feel weak, have nasal congestion, or experience sexual side effects like difficulty urinating or impotence. Skin discoloration, agitation, or confusion can also occur. These effects are usually mild but should be reported if they become bothersome.
More serious side effects are rare but may require urgent medical care. These include seizures, muscle stiffness, high fever, or uncontrollable movements of the face or body—signs of serious conditions like neuroleptic malignant syndrome or tardive dyskinesia. Allergic reactions such as trouble breathing, swelling, or rash may also occur. Contact your doctor or go to the emergency room if you notice any serious symptoms.
Largactil Product Monograph. Haymarket, NSW: Healthdirect; 2023.
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