Cefepime Injection (Cefepime)

Description

Cefepime Injection (Cefepime) is an antibiotic used to treat a wide variety of bacterial infections. It belongs to a class of drugs known as cephalosporin antibiotics and works by stopping the growth of bacteria. This medication is typically administered by healthcare professionals and is often used in a hospital or clinical setting to treat severe infections, including pneumonia, urinary tract infections, and infections of the skin or abdominal cavity.

Directions

The Cefepime Injection dosage must be determined by a healthcare provider and is usually administered as an IV (intravenous) or IM (intramuscular) injection. An example of a potential dosage is 0.5 g to 2 g every 12 hours for 7 to 10 days. The dosage may be based on the type and severity of the infection, your weight, age, and kidney function.

Follow your healthcare provider's instructions carefully. If you are administering cefepime at home, make sure you understand how to properly mix and give the injection.

Ingredients

Each vial of Cefepime for injection contains cefepime hydrochloride, typically in a strength of 0.5 g, 1 g, or 2 g.

Contraindications

Do not use Cefepime if you are allergic to cefepime or other cephalosporin or penicillin antibiotics.

Cautions

• Before you start using Cefepime, inform your healthcare provider about:
• Any allergies you have
• Any medications you take, including prescription and over-the-counter medications
• Any health conditions you have
• If you are pregnant or plan to become pregnant
• If you are nursing or plan to nurse your baby
• Cefepime therapy may need to be carefully monitored by healthcare professionals to detect any signs of superinfection or secondary infection during treatment.
• Complete the entire course of Cefepime as prescribed, even if symptoms improve before the medication is finished, to prevent the potential for antibiotic resistance.
• People on Cefepime may need to be monitored for neurological signs and symptoms, especially those with pre-existing neurological disorders or renal impairment. These events may include headaches, confusion, or even seizures.
• Cefepime may cause an increased risk of bleeding. Patients with a history of clotting disorders, or those taking anticoagulant medications, should be closely monitored while on Cefepime.
• If you experience a rash, hives, or other signs of an allergic reaction, seek medical attention immediately.
• Consult a healthcare provider if symptoms do not improve or worsen after beginning treatment with Cefepime.
• Cefepime administration may be associated with local reactions at the injection site, such as redness or swelling. Report any unusual reactions to your healthcare provider.
• Always follow the instructions provided by your healthcare provider or pharmacist for the proper mixing and administration of Cefepime injections.

Side Effects

The most common side effects of Cefepime injections include local reactions like pain or inflammation at the injection site, diarrhea, nausea, vomiting, and headache. Serious side effects may include seizures, hallucinations, allergic reactions, and severe diarrhea. Call your doctor right away if you experience any side effects that worsen or persist.

References:

1. Cefepime Injection Prescribing Information. Lake Forest, IL: Hospira, Inc.; 2021.
2. Maxipime (cefepime injection) Dosage Information. DailyMed. Accessed August 9, 2023.

About Dr. Gerardo Sison (Page Author)

An honors graduate of the University of Florida, Dr. Sison started his pharmacy career in a community setting, extending his services to hospitals and clinics over time. He has also worked in medication therapy management, advising patients on proper medication use for their chronic health conditions. Read More....