Ycanth (Cantharidin)

Also Known as Cantharone

Prescription medicineOnly Available By Prescription

Top brand choice

Strength Pack Size Qty
Strength
Regular 0.7%
Pack Size
Qty
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What is a Generic Drug?

A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.

The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.

Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.

Description

Ycanth is a topical solution used to treat molluscum contagiosum in adults and children ages 2 and older. Molluscum is a contagious viral skin infection that causes small, firm, dome-shaped bumps, often with a dip in the center. It can spread through skin-to-skin contact or by sharing items such as towels and toys. A healthcare professional typically applies it directly to each bump in a clinic. It causes a small blister to form under the treated bump, which then dries, crusts, and falls away. The exact way cantharidin works against molluscum is not fully known.

Fact Table

Formula

C10H12O4

License

US FDA (NDA 212905)

Bioavailability

Absolute bioavailability not established; systemic absorption is low following topical administration

Legal status

Rx only

Chemical Name

1,2-Dimethyl-3,6-epoxyperhydrophthalic anhydride (Cantharidin)

Elimination half-life

Not established

Dosage (Strength)

0.7% topical solution (7mg/mL); each single-use applicator contains approximately 0.45mL; apply once to each lesion every 3 weeks as needed, using no more than 2 applicators per treatment session

Pregnancy

No adequate human pregnancy data; systemic exposure after topical use is low and fetal exposure is not expected

Brands

Ycanth, Cantharone

Protein binding

Not established

PubChem CID

5944

MedlinePlus

a623044

ChEBI

64213

ATC code

Not assigned

DrugBank

DB12328

KEGG

D11745

Routes of administration

Topical

Directions

A healthcare professional typically applies Ycanth after being trained to use it safely. It's important to wear gloves and eye protection, check the applicator for damage, and open it using the supplied tool. If an applicator is cracked or broken, it is placed in a sharps container and not used.

Ycanth is applied once to each wart or bump, using no more than two applicators per visit. It is for use on the skin only and must be kept away from the eyes, mouth, other moist body areas, and healthy skin. Any accidental contact should be wiped off immediately.

Treatment may be repeated every three weeks until the bumps clear, and the treated area should be washed with soap and water after 24 hours, or sooner if a severe skin reaction occurs.

Ingredients

The active ingredient in Ycanth is cantharidin. Inactive ingredients may include acetone, camphor, castor oil, denatonium benzoate, ethanol 32%, gentian violet, hydroxypropyl cellulose, and nitrocellulose.

Cautions

  • Before using this medication, you may want to consult a healthcare provider about the following:
    • Any existing health conditions
    • Any allergies
    • A list of all medications currently being taken
  • Do not swallow this solution. Taking cantharidin by mouth can cause life-threatening or fatal poisoning, which is why the formula carries a bitter agent and why the treated area must stay away from the mouth after application.
  • Keep the solution away from the eyes. If any reaches an eye, flush it with water for at least 15 minutes and get medical attention.
  • Stop a child from touching, licking, or sucking a treated spot, and cover it if needed.
  • Treat both the applicator and the treated skin as flammable, even after the solution dries. Stay clear of fire, flame, and cigarettes until it has been washed off.
  • Expect blistering, since vesicles at the treated site are how the medicine works. Tell your healthcare provider if the reaction turns severe, because they may wash it off before the 24-hour mark.
  • Wash the area with soap and water at 24 hours exactly as instructed rather than leaving the solution on longer.
  • Do not let it near the eyes or onto mucous membranes such as the lips, the inside of the nose, or the genital area.
  • Tell your healthcare provider if treated skin becomes painful, oozes pus, or develops redness, since molluscum lesions can become infected.
  • Ask about pigment changes if you have a deeper skin tone, since the label lists potential discoloration at the application site.
  • Store applicators where children cannot reach them, and put used ones in a sharps container.

Contraindications

There are no contraindications for Ycanth in the drug label.

Side Effects

Common side effects of Ycanth include:

  • Blistering at the treated site
  • Pain
  • Itching
  • Scabbing
  • Redness
  • Skin discolouration
  • Dryness
  • Swelling
  • Broken skin where it was applied

Contact your healthcare provider if blistering, pain, or redness extends beyond the treated lesion, or if you notice pus, red streaks, or a fever. Get immediate medical care for widespread blistering, trouble breathing, or swelling of the face, lips, or throat.

References

Ycanth Prescribing Information. West Chester, PA: Verrica Pharmaceuticals Inc.; 2023.

Ycanth Drug Label Information. West Chester, PA: Verrica Pharmaceuticals Inc.; 2023.




IMPORTANT NOTE: The information provided above is for general awareness and educational purposes only. It is not intended to diagnose, treat, or replace professional medical or veterinary advice. Always consult your physician, pharmacist, or veterinarian regarding the safety, suitability, and proper use of any medication for yourself or your pet.

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