Cagrilintide

Prescription medicineOnly Available By Prescription

What if I find a lower price with another pharmacy?

We guarantee the lowest price on all of our prescription products. If you find your medications cheaper at any other recognized licensed mail order pharmacy, we will not only match their price, we will beat it by 25% of the difference. It is our 125% price match guarantee!

Example: If you find a product on Canada Drugs Direct for $50.00 and find the same product for $40.00 at another mail order pharmacy, we will provide you with a $12.50 discount, bringing your total to $37.50.

To get the discount please make sure to mention the price match to the customer service team when they call to collect payment for your order. Or call toll free at 1-888-904-8467 to place the order through the phone.

Terms & Conditions of Program

  • Guaranteed lowest price is only valid at the time of sale.
  • We will only match the current advertised price.
  • Products must be identical and in stock at the time of placing an order with a licensed mail order pharmacy. They must be an online Canadian pharmacy with an address in Canada.
  • Products must be authentic in brand and size (same manufacturer, same country of manufacture, same pack size, same strength and same quantity).
  • Products must be new. We cannot match the price of any used, short expiry or expired product.
  • Price match can only be issued over the phone with our customer service team. Please note at this time we cannot offer price matching for the products Ozempic or Saxenda.
What is a Generic Drug?

A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.

The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.

Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.

Description

Cagrilintide is an investigational long-acting amylin analogue developed for the treatment of obesity and overweight in individuals with or without type 2 diabetes. It mimics the physiological effects of endogenous amylin, a hormone co-secreted with insulin, to regulate appetite and food intake. Cagrilintide works by delaying gastric emptying and increasing satiety signals in the brain, leading to reduced caloric intake and body weight. It is being evaluated as a once-weekly subcutaneous injection, often in combination with GLP-1 receptor agonists such as semaglutide, to enhance weight loss outcomes.

Fact Table

Formula

C289H440N78O88S1

License

Investigational

Bioavailability

~85% (subcutaneous)

Legal status

Investigational

Chemical Name

Cagrilintide (AC-960)

Elimination half-life

6–8 days

Dosage (Strength)

0.3 mg to 4.5 mg weekly (in trials)

Pregnancy

Not recommended (insufficient data)

Brands

Not marketed yet

Protein binding

>99%

PubChem CID

145996392

MedlinePlus

Not listed

ChEBI

Not available

ATC code

None assigned

DrugBank

DB16495

KEGG

Not listed

Routes of administration

Subcutaneous injection

Directions

As an investigational agent, Cagrilintide is administered subcutaneously under the supervision of a healthcare provider in a clinical trial setting. In studies, it has been dosed once weekly, with titration to target doses based on tolerability and treatment response. Final dosage and administration schedules are subject to trial protocols or future regulatory guidance.

Ingredients

Active Ingredient: Cagrilintide (a modified amylin analogue) Full excipient details will be disclosed upon regulatory approval or expanded access availability.

Contraindications

Cagrilintide is not yet approved for general use and is currently contraindicated outside clinical research settings. Potential contraindications, based on its mechanism of action, may include:

  • Hypersensitivity to amylin analogues
  • History of severe gastrointestinal disease, such as gastroparesis
  • Patients with a history of medullary thyroid carcinoma or MEN2 (in combination therapy with GLP-1RAs)

Cautions

Use is limited to controlled clinical settings. Patients should be monitored for gastrointestinal adverse effects, hypoglycemia (especially if used with insulin or insulin secretagogues), and changes in appetite or weight. The combination of Cagrilintide with other incretin-based therapies may enhance efficacy but also risk of gastrointestinal intolerance. Long-term cardiovascular and endocrine effects are under investigation.

Side Effects

  • Nausea
  • Constipation
  • Vomiting
  • Decreased appetite
  • Injection site reactions
  • Possible hypoglycemia (especially with concomitant antidiabetic medications)

IMPORTANT NOTE: The information provided above is for general awareness and educational purposes only. It is not intended to diagnose, treat, or replace professional medical or veterinary advice. Always consult your physician, pharmacist, or veterinarian regarding the safety, suitability, and proper use of any medication for yourself or your pet.

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