Bumex (Bumetanide)

Also Known as Burinex

Prescription medicineOnly Available By Prescription

Top brand choice

Strength Pack Size Qty
Strength
1mg
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Top Generic choice

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Strength
1mg
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What if I find a lower price with another pharmacy?

We guarantee the lowest price on all of our prescription products. If you find your medications cheaper at any other recognized licensed mail order pharmacy, we will not only match their price, we will beat it by 25% of the difference. It is our 125% price match guarantee!

Example: If you find a product on Canada Drugs Direct for $50.00 and find the same product for $40.00 at another mail order pharmacy, we will provide you with a $12.50 discount, bringing your total to $37.50.

To get the discount please make sure to mention the price match to the customer service team when they call to collect payment for your order. Or call toll free at 1-888-904-8467 to place the order through the phone.

Terms & Conditions of Program

  • Guaranteed lowest price is only valid at the time of sale.
  • We will only match the current advertised price.
  • Products must be identical and in stock at the time of placing an order with a licensed mail order pharmacy. They must be an online Canadian pharmacy with an address in Canada.
  • Products must be authentic in brand and size (same manufacturer, same country of manufacture, same pack size, same strength and same quantity).
  • Products must be new. We cannot match the price of any used, short expiry or expired product.
  • Price match can only be issued over the phone with our customer service team. Please note at this time we cannot offer price matching for the products Ozempic or Saxenda.
What is a Generic Drug?

A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.

The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.

Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.

Description

Bumex is a loop diuretic, also known as a water pill, that helps remove extra fluid from the body. It is often used to treat swelling caused by conditions like heart problems, liver disease, or kidney issues. This medicine works by stopping the body from keeping too much salt, which then leaves the body through urine. This helps reduce the swelling. Bumetanide usually comes as tablets that you take by mouth.

Fact Table

Formula

C17H20N2O5S

License

US FDA

Bioavailability

~80–90%

Legal status

Prescription only (Rx)

Chemical Name

Bumetanide

Elimination half-life

1–1.5 hours

Dosage (Strength)

0.5 mg, 1 mg, 2 mg oral tablets; 0.25 mg/mL IV injection

Pregnancy

Category C – Use with caution

Brands

Bumex

Protein binding

95%

PubChem CID

2471

MedlinePlus

a682602

ChEBI

3213

ATC code

C03CA02

DrugBank

DB00887

KEGG

D00256

Routes of administration

Oral, Intravenous (IV)

Directions

Bumex is typically taken by mouth. When using tablets, it's important to swallow them whole with a drink of water. The standard Bumex dosage ranges from 0.5 mg to 2 mg per day, often given as a single dose. It's possible to repeat the dose in 4 to 5 hours if needed, but the total daily dose should not exceed 10 mg per day. Some people may follow an intermittent dosing schedule for managing edema. This involves taking Bumex on alternate days or for 3 to 4 days with a rest period of 1 to 2 days.

Ingredients

The active ingredient in Bumex is bumetanide.

Contraindications

Avoid taking or using this medication if any of the following apply:

  • Anuria (lack of urine production)
  • Severe electrolyte depletion
  • Hepatic encephalopathy (brain problem caused by severe liver disease)
  • Hypersensitivity to bumetanide or related compounds
  • Severe kidney impairment

Cautions

  • Before taking Bumex, you may want to consult a healthcare provider about the following:
    • Any existing health conditions
    • Any allergies
    • A list of all medications you are currently taking
    • Whether you are pregnant or breastfeeding
  • Bumex is a powerful water pill used to help get rid of excess fluid. If too much is taken or taken too often, it can cause dehydration, low blood pressure, and dangerous imbalances in minerals like potassium, sodium, and magnesium.
  • Bumex can cause your potassium levels to drop, which may lead to muscle cramps, weakness, or irregular heartbeats. You’re at higher risk if you have heart failure, liver problems, certain kidney issues, or if you’re taking other medications that also lower potassium.
  • Very high doses or frequent injections of Bumex—especially in people with kidney problems—may increase the risk of hearing loss. This is rare but has been seen in lab animals. Be sure to let your doctor know if you notice any changes in your hearing while using this medication.
  • If you’re allergic to sulfa drugs, you may also react to Bumex. Signs of a serious allergic reaction include rash, itching, swelling, or trouble breathing—seek medical help immediately if these occur.
  • Bumex should only be used in pregnancy if absolutely necessary. It may affect the baby’s growth and development in very high doses. It’s not known if Bumex passes into breast milk—so nursing is not recommended while taking this medication.
  • Bumex is not approved for use in children. For older adults, lower doses may be needed because kidney function can decline with age, increasing the risk of side effects.

Side Effects

The most common side effects of Bumex include muscle cramps, dizziness, low blood pressure, headache, nausea, and mental confusion in people with liver disease. These reactions occurred in about 4% of patients and are typically mild. Less frequent side effects include rash, hearing changes, weakness, and abdominal or joint pain. Serious skin reactions like Stevens-Johnson syndrome and toxic epidermal necrolysis have also been reported.

Some patients may experience changes in lab values, such as low potassium, sodium, or chloride levels, or increased uric acid, blood sugar, and creatinine. Rare side effects include dehydration, dry mouth, erectile issues, chest pain, and fatigue. Bumex may also affect blood counts or liver enzymes, especially with high or prolonged doses. Talk to your healthcare provider if you notice symptoms like extreme tiredness, confusion, itching, or unusual bleeding.

References

  1. Bumex (bumetanide) Product Monograph. Parsippany, NJ: Validus Pharmaceuticals LLC; 2023.
  2. Bumex (bumetanide) Drug Label Information. Parsippany, NJ: Validus Pharmaceuticals LLC; 2023.


IMPORTANT NOTE: The information provided above is for general awareness and educational purposes only. It is not intended to diagnose, treat, or replace professional medical or veterinary advice. Always consult your physician, pharmacist, or veterinarian regarding the safety, suitability, and proper use of any medication for yourself or your pet.

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