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Buccastem (Prochlorperazine)

Prescription medicineOnly Available By Prescription

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What if I find a lower price with another pharmacy?

We guarantee the lowest price on all of our prescription products. If you find your medications cheaper at any other recognized licensed mail order pharmacy, we will not only match their price, we will beat it by 25% of the difference. It is our 125% price match guarantee!

Example: If you find a product on Canada Drugs Direct for $50.00 and find the same product for $40.00 at another mail order pharmacy, we will provide you with a $12.50 discount, bringing your total to $37.50.

To get the discount please make sure to mention the price match to the customer service team when they call to collect payment for your order. Or call toll free at 1-888-904-8467 to place the order through the phone.

Terms & Conditions of Program

  • Guaranteed lowest price is only valid at the time of sale.
  • We will only match the current advertised price.
  • Products must be identical and in stock at the time of placing an order with a licensed mail order pharmacy. They must be an online Canadian pharmacy with an address in Canada.
  • Products must be authentic in brand and size (same manufacturer, same country of manufacture, same pack size, same strength and same quantity).
  • Products must be new. We cannot match the price of any used, short expiry or expired product.
  • Price match can only be issued over the phone with our customer service team. Please note at this time we cannot offer price matching for the products Ozempic or Saxenda.
What is a Generic Drug?

A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.

The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.

Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.


BUCCASTEM (prochlorperazine) is a medication prescribed to treat nausea and vomiting. It is a buccal tablet, which means it's placed between the gums and the lips, where it slowly releases medication over one to two hours.

Prochlorperazine is available in the United States, but this particular buccal formulation is not. 

BUCCASTEM works by blocking dopamine receptors in the brain. Dopamine is responsible for several functions of the body, including temperature regulation, muscle tone, and vomiting. By blocking these receptors, BUCCASTEM helps to treat nausea and vomiting.


Take BUCCASTEM exactly as directed by your doctor. 

The normal dose is 3-6 mg by mouth between the lips and gums twice daily. Leave BUCCASTEM in place for one to two hours while it slowly dissolves. Do not move BUCCASTEM around, as this may cause it to dissolve too quickly and increase certain side effects.

Do not take BUCCASTEM longer than two days unless directed by your doctor.


The active ingredient in BUCCASTEM is prochlorperazine. It comes as BUCCASTEM 3 mg tablets.


BUCCASTEM has drug interactions with the following types of medications:

  • Anticholinergic medications
  • Anticoagulants
  • Antiseizure medications
  • Blood pressure medications
  • Levodopa
  • Lithium 
  • Sedatives

Tell your doctor if you use any medications in these classes before you start using BUCCASTEM.


Tell your doctor if you have a history of low blood pressure or heart problems.

BUCCASTEM may increase the risk of falls, especially in older adults and those with low blood pressure.

Tell your doctor if you experience any visual problems while taking BUCCASTEM.

Side Effects

Common BUCCASTEM side effects include:

  • Agitation
  • Altered taste
  • Changes in blood sugar
  • Convulsions or tremor
  • Dizziness
  • Drowsiness
  • Dry mouth
  • Insomnia
  • Low blood pressure
  • Nausea
  • Numbness of the mouth
  • Restlessness or anxiety
  • Sensitivity to the sun
  • Skin reactions
  • Upper respiratory infection
  • Vomiting


Buccastem [package insert].Hereford, UK: Alliance Pharmaceuticals; 2020.

IMPORTANT NOTE: The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.

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