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Breztri Aerosphere (budesonide, glycopyrrolate, and formoterol fumarate)

Prescription medicineOnly Available By Prescription

Top brand choice

Strength Pack Size Qty
160mcg/7.2mcg/5mcg (same as 160mcg/9mcg/4.8mcg) (120 doses/Inhaler)
Pack Size
160mcg/9mcg/4.8mcg (same as 160mcg/7.2mcg/5mcg) (120 doses/inhaler)
Pack Size

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What if I find a lower price with another pharmacy?

We guarantee the lowest price on all of our prescription products. If you find your medications cheaper at any other recognized licensed mail order pharmacy, we will not only match their price, we will beat it by 25% of the difference. It is our 125% price match guarantee!

Example: If you find a product on Canada Drugs Direct for $50.00 and find the same product for $40.00 at another mail order pharmacy, we will provide you with a $12.50 discount, bringing your total to $37.50.

To get the discount please make sure to mention the price match to the customer service team when they call to collect payment for your order. Or call toll free at 1-888-904-8467 to place the order through the phone.

Terms & Conditions of Program

  • Guaranteed lowest price is only valid at the time of sale.
  • We will only match the current advertised price.
  • Products must be identical and in stock at the time of placing an order with a licensed mail order pharmacy. The must be a member of CIPA (Canadian International Pharmacy Association).
  • Products must be authentic in brand and size (same manufacturer, same country of manufacture, same pack size, same strength and same quantity).
  • Products must be new. We cannot match the price of any used, short expiry or expired product.
  • Price match can only be issued over the phone with our customer service team
What is a Generic Drug?

A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.

The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.

Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.


Breztri Aerosphere is an inhaler that contains three drugs used to treat patients suffering from chronic obstructive pulmonary disease (COPD).

Budesonide (inhaled corticosteroid), glycopyrrolate (anticholinergic), and formoterol fumarate (long-acting beta2-adrenergic agonist) are contained in Breztri Aerosphere.


Breztri comes as a pressurized metered dose inhaler. You should inhale the contents of Breztri by mouth. Each puff supplies 160 mcg of budesonide, 9 mcg of glycopyrrolate, and 4.8 mcg of formoterol fumarate. 

Maintenance COPD treatment dosing is 2 puffs by mouth two times a day. To prevent thrush, an oral fungal infection, you should rinse your mouth with water and spit it out after using Breztri. 

You should administer per the instructions on your prescription label. Talk to your doctor or pharmacist if you have any questions about how to use your inhaler.

You should not use Breztri to relieve the sudden onset of breathing trouble.


Micronized budesonide, micronized glycopyrrolate, and micronized formoterol fumarate are the active ingredients contained in Breztri Aerosphere.


Avoid using Breztri if you have any allergies to budesonide, glycopyrrolate, formoterol fumarate, or any of the other ingredients contained in Breztri. 


  • Before you start using Breztri Aerosphere, inform your doctor:
    • Of your allergies
    • Of all the medications you take, especially any inhalers, atropine, antifungal medications, and anti-HIV medications
    • Of your health conditions
    • If you are pregnant or have plans to become pregnant
    • If you are currently breastfeeding or have plans to breastfeed
  • You should not use Breztri with other medications that contain a long-acting beta2-adrenergic agonist due to an overdose risk.
  • Your risk for pneumonia is increased with the use of Breztri. Contact your doctor right away if you experience a fever, cough, chills, worsening breathing problems, mucus production, or mucus color changes.
  • Infections can be worsened with Breztri use.
  • When being switched from a systemic corticosteroid to an inhaled corticosteroid, your adrenal function can be affected. When switching to an inhaled corticosteroid, you should be slowly tapered off systemic corticosteroids.
  • Very high doses of Breztri can cause adrenal insufficiency and hypercorticism. Normal doses of Breztri can also cause these effects in sensitive patients. Contact your doctor right away if you develop weakness, nausea, vomiting, tiredness, no energy, or low blood pressure.
  • If you develop sudden breathing problems after using Breztri, stop taking Breztri and immediately contact your doctor. 
  • Let your doctor know about any heart problems you have.
  • Let your doctor know about any liver or kidney problems you have.
  • Let your doctor know if your bones are weak or thin (osteoporosis).
  • Let your doctor know if you have glaucoma, cataracts, or other vision problems.
  • Let your doctor know if you have a convulsive disorder, thyroid problems, diabetes, or ketoacidosis.
  • Urinary retention can worsen or be caused by Breztri. Contact your doctor right away if you have trouble urinating, painful urination, frequent urination, or urination in drips or a weak stream.
  • Low potassium levels can be caused by Breztri. Immediately contact your doctor if you develop muscle twitches, muscle weakness, or irregular heart rhythm.
  • Your blood sugar levels can increase with the use of Breztri.
  • Breztri Aerosphere should be stored at room temperature.

Side Effects

Breztri Aerosphere can cause the following side effects: back pain, thrush, influenza, muscle spasm, diarrhea, urinary tract infection, upper respiratory tract infection, pneumonia, and sinusitis.

These are not all the potential side effects that can be caused by Breztri Aerosphere. Call your doctor if you experience negative or persistent side effects.


  1. Breztri Aerosphere. Wilmington, DE: AstraZeneca Pharmaceuticals LP; 2021.
  2. Breztri Aerosphere. Wilmington, DE: AstraZeneca Pharmaceuticals LP; 2021.

IMPORTANT NOTE: The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.

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