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Example: If you find a product on Canada Drugs Direct for $50.00 and find the same product for $40.00 at another mail order pharmacy, we will provide you with a $12.50 discount, bringing your total to $37.50.
To get the discount please make sure to mention the price match to the customer service team when they call to collect payment for your order. Or call toll free at 1-888-904-8467 to place the order through the phone.
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A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.
The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.
Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.
Breyna is a prescription combination inhaler that contains budesonide, an inhaled corticosteroid, and formoterol, a long-acting bronchodilator. It’s used to help control asthma in patients 6 years and older and may also be prescribed for chronic obstructive pulmonary disease (COPD). The budesonide reduces airway inflammation, while formoterol relaxes the airway muscles to improve breathing. Breyna comes as a metered-dose inhaler in two strengths (80/4.5 mcg and 160/4.5 mcg per inhalation).
Fact Table | |
Formula | C25H34O6 (Budesonide), C25H37NO4 (Formoterol fumarate) |
License | US FDA |
Bioavailability | Budesonide: 39%; Formoterol: 61% |
Legal status | Rx-only |
Chemical Name | Budesonide and Formoterol fumarate dihydrate |
Elimination half-life | Budesonide: 2-3 hours; Formoterol: 10 hours |
Dosage (Strength) | 80mcg/4.5mcg and 160mcg/4.5mcg inhalation aerosol |
Pregnancy | Use during pregnancy only if clearly needed |
Brands | Breyna, Symbicort |
Protein binding | Budesonide: 85-90%; Formoterol: 50% |
PubChem CID | 5281004 (Budesonide), 3086833 (Formoterol) |
MedlinePlus | a623046 |
ChEBI | 31687 (Budesonide), 6687 (Formoterol) |
ATC code | R03AK07 |
DrugBank | DB01222 (Budesonide), DB00983 (Formoterol) |
KEGG | D00446 (Budesonide), D07543 (Formoterol) |
Routes of administration | Inhalation |
The usual dosage is 2 inhalations in the morning and 2 in the evening, about 12 hours apart. It’s important to use the inhaler correctly:
Always rinse your mouth with water after use to help prevent throat irritation or infections.
Before using the inhaler for the first time—or if it hasn’t been used for more than 7 days—you’ll need to prime it by shaking, pointing it away from your face, and releasing test sprays.
The inhaler comes with a built-in dose counter to track how much medicine is left, since it may not feel empty even when it runs out.
Breyna contains two active ingredients: budesonide and formoterol fumarate dihydrate.
Before taking this medication, you may want to consult a healthcare provider about the following:
Breyna should always be used with an inhaled corticosteroid (ICS), not by itself, for asthma. Using the long-acting medicine alone (LABA monotherapy) has been linked to serious risks, including hospitalization and even death, especially in children and teens.
This inhaler is not for sudden breathing problems or asthma attacks. For fast relief, a rescue inhaler (short-acting bronchodilator) should be used instead.
Do not take more doses than prescribed or combine Breyna with other LABA medicines. Overuse may cause dangerous heart problems or other serious side effects.
Rinse your mouth with water after each use to reduce the chance of getting a yeast infection in the mouth or throat. If you notice white patches or soreness, let your doctor know.
People with COPD may have a higher risk of pneumonia and lung infections while using Breyna. Contact your doctor if you develop fever, cough with mucus, or chest pain.
Because Breyna contains a steroid, it may weaken your immune system. Avoid close contact with people who have infections like chickenpox or measles if you haven’t had them or been vaccinated.
Long-term use of inhaled steroids may reduce bone strength, slow growth in children, or raise the risk of eye problems like cataracts or glaucoma. Regular checkups with your doctor can help monitor for these effects.
Breyna may also cause changes in blood sugar, potassium levels, or heart rhythm in some patients. Tell your doctor if you have diabetes, heart disease, or other ongoing health conditions.
Avoid taking this medication if any of the following apply:
The most common side effects of Breyna are mild breathing or throat problems, such as nasal congestion, sore throat, sinus infections, or cough. Some people also experience headache, back pain, stomach upset, or nausea and vomiting. Infections like colds, flu, or bronchitis have been reported, and oral yeast infections (thrush) can occur with inhaled steroids.
More serious side effects are less common but can include pneumonia in people with COPD, worsening asthma, or irregular heart rhythms. Using inhaled steroids for a long time may raise the risk of glaucoma, cataracts, slowed growth in children, or adrenal problems. Rarely, severe allergic reactions such as swelling, rash, or trouble breathing may occur. Anyone with serious or ongoing side effects should contact their healthcare provider.
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