Bonefos (Clodronate Disodium)

Prescription medicineOnly Available By Prescription

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What if I find a lower price with another pharmacy?

We guarantee the lowest price on all of our prescription products. If you find your medications cheaper at any other recognized licensed mail order pharmacy, we will not only match their price, we will beat it by 25% of the difference. It is our 125% price match guarantee!

Example: If you find a product on Canada Drugs Direct for $50.00 and find the same product for $40.00 at another mail order pharmacy, we will provide you with a $12.50 discount, bringing your total to $37.50.

To get the discount please make sure to mention the price match to the customer service team when they call to collect payment for your order. Or call toll free at 1-888-904-8467 to place the order through the phone.

Terms & Conditions of Program

  • Guaranteed lowest price is only valid at the time of sale.
  • We will only match the current advertised price.
  • Products must be identical and in stock at the time of placing an order with a licensed mail order pharmacy. They must be an online Canadian pharmacy with an address in Canada.
  • Products must be authentic in brand and size (same manufacturer, same country of manufacture, same pack size, same strength and same quantity).
  • Products must be new. We cannot match the price of any used, short expiry or expired product.
  • Price match can only be issued over the phone with our customer service team. Please note at this time we cannot offer price matching for the products Ozempic or Saxenda.
What is a Generic Drug?

A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.

The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.

Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.


Chemical Name: Clodronate (KLA-dronayt)

Bisphosphonates, such as clodronate (BONEFOS), are used to treat problems arising from malignant tumors that have metastasized to sites in the skeleton. Clodronate (BONEFOS) is used for the treatment and prevention of hypercalcaemia, bone pain, and fractures due to malignant osteolysis, "erosion of bone", especially in breast cancer, multiple myeloma, and prostate cancer. Clodronate (BONEFOS) treats the harmful effects of cancer in your bones by reducing the risk of fractures, normalizing the elevated levels of calcium in your blood, relieves bone pain and protects your bones from further damage. Clodronate (BONEFOS) acts by inhibiting the process of formation of tumor metastases in the bones. Osteolysis, the abnormal destruction of bone, happens due to increased activity of the bone resorbing cells, called osteoclasts. BONEFOS effectively inhibits the activity of these cells.


SIDE EFFECTS that may occur while taking this medication include diarrhea, nausea and skin rashes.

Side Effects

You might experience a few side effects including

  • Diarrhea
  • Loss of appetite
  • Nausea
  • Stomach ache
  • Vomiting
  • Difficulty breathing
  • Pain in mouth
  • Muscle cramping
  • Skin rash
  • Swelling
  • Unexplainable fatigue
Also, if you suffer from any other issues, such as kidney problems or deteriorating jaw bone due to this medicine, immediately report it to your doctor.
IMPORTANT NOTE: The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.

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