Binosto (Alendronate Sodium)

Prescription medicineOnly Available By Prescription

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What if I find a lower price with another pharmacy?

We guarantee the lowest price on all of our prescription products. If you find your medications cheaper at any other recognized licensed mail order pharmacy, we will not only match their price, we will beat it by 25% of the difference. It is our 125% price match guarantee!

Example: If you find a product on Canada Drugs Direct for $50.00 and find the same product for $40.00 at another mail order pharmacy, we will provide you with a $12.50 discount, bringing your total to $37.50.

To get the discount please make sure to mention the price match to the customer service team when they call to collect payment for your order. Or call toll free at 1-888-904-8467 to place the order through the phone.

Terms & Conditions of Program

  • Guaranteed lowest price is only valid at the time of sale.
  • We will only match the current advertised price.
  • Products must be identical and in stock at the time of placing an order with a licensed mail order pharmacy. They must be an online Canadian pharmacy with an address in Canada.
  • Products must be authentic in brand and size (same manufacturer, same country of manufacture, same pack size, same strength and same quantity).
  • Products must be new. We cannot match the price of any used, short expiry or expired product.
  • Price match can only be issued over the phone with our customer service team. Please note at this time we cannot offer price matching for the products Ozempic or Saxenda.
What is a Generic Drug?

A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.

The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.

Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.


Binosto is a unique formulation of alendronate sodium that dissolves in water for people with difficulty swallowing. Binosto can be prescribed for postmenopausal women with osteoporosis or men with osteoporosis.

Binosto helps to slow the breakdown of bone and, in some cases, rebuild it. The bones matrix includes osteoclasts, which are always breaking down bone, and osteoblasts, which are always rebuilding it. 

Binosto incorporates into the bone matrix to prevent osteoclasts from breaking down bone. After several years of usage, Binosto can rebuild bone mass.

Fact Table







Legal status


Chemical Name

Alendronic acid

Elimination half-life

126 months

Dosage (Strength)



Not Recommended


Fosamax, Binosto

Protein binding


PubChem CID






ATC code






Routes of administration

By mouth


Take one Binosto 70 mg tablet by mouth once weekly.

Binosto should not be swallowed whole. Dissolve the tablet in 4 oz of room temperature water, waiting five minutes for it to dissolve fully. Stir the contents for 10 seconds, and consume the contents.

Do not lie down for 30 minutes after taking Binosto and do not eat or drink anything for 30 minutes.


Alendronate sodium is the active ingredient in Binosto effervescent tablets. 


Common drug-drug interactions with Binosto may include:

  • Aminoglycosides
  • Aspirin
  • Ibuprofen
  • Naproxen
  • Parathyroid hormone
  • Proton pump inhibitors


Tell your doctor if you have a history of low blood calcium or calcium problems. 

Tell your doctor if you have a history of kidney problems before starting Binosto.

Rare side effects of Binosto include osteonecrosis of the jaw and atypical femur fractures.

Do not take Binosto if you are on a sodium restricted diet.

Side Effects

Common adverse reactions to Binosto may include:

  • Abdominal pain
  • Acid regurgitation
  • Atypical femur fractures
  • Constipation
  • Decreased serum phosphate
  • Diarrhea
  • Dyspepsia
  • Headache
  • Hypocalcemia
  • Musculoskeletal pain
  • Nausea
  • Osteonecrosis of the jaw


Binosto [package insert]. San Antonio, TX: Mission Pharmacal; 1995.

IMPORTANT NOTE: The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.

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