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What if I find a lower price with another pharmacy?

We guarantee the lowest price on all of our prescription products. If you find your medications cheaper at any other recognized licensed mail order pharmacy, we will not only match their price, we will beat it by 25% of the difference. It is our 125% price match guarantee!

Example: If you find a product on Canada Drugs Direct for $50.00 and find the same product for $40.00 at another mail order pharmacy, we will provide you with a $12.50 discount, bringing your total to $37.50.

To get the discount please make sure to mention the price match to the customer service team when they call to collect payment for your order. Or call toll free at 1-888-904-8467 to place the order through the phone.

Terms & Conditions of Program

  • Guaranteed lowest price is only valid at the time of sale.
  • We will only match the current advertised price.
  • Products must be identical and in stock at the time of placing an order with a licensed mail order pharmacy. The must be a member of CIPA (Canadian International Pharmacy Association).
  • Products must be authentic in brand and size (same manufacturer, same country of manufacture, same pack size, same strength and same quantity).
  • Products must be new. We cannot match the price of any used, short expiry or expired product.
  • Price match can only be issued over the phone with our customer service team
What is a Generic Drug?

A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.

The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.

Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.


Berberine is a yellow-colored compound extracted from various plants like barberry and goldenseal. It's categorized as an isoquinoline alkaloid, which is a type of naturally occurring chemical substance known for various biological effects. The benefits of berberine may include the management of several conditions, including diabetes, high cholesterol, and high blood pressure. As a dietary supplement, berberine is not regulated as a prescription medication.


Berberine typically comes as an oral supplement. The dosage can vary but is generally 500 mg two to three times daily, taken before or with meals to help with absorption. It’s recommended to consult a healthcare professional, as berberine can interact with various medications. Long-term monitoring may be needed to assess the drug’s effects on the body.


Berberine is an alkaloid extracted from various plants, including the genera Berberis (e.g., barberry), Hydrastis (goldenseal), and Mahonia (Oregon grape). It is traditionally sourced from the roots, bark, and stems and appears as a yellow compound that contributes to the plants' color.


While berberine has shown potential benefits, it's important for individuals to be aware of certain contraindications. You should avoid taking berberine if any of the following apply:

  • Pregnancy: Berberine can potentially cause harm to the fetus and should not be used during pregnancy.
  • Infancy and Early Childhood: Due to possible risks, infants and young children should not take berberine.
  • Liver Disease: Individuals with liver problems should exercise caution as berberine may worsen liver issues.


  • Before taking berberine, you may want to consult a doctor or healthcare provider about:
    • Any medical conditions you have.
    • Other medications you take.
    • Whether you have allergic reactions to any medications.
  • Avoid combining berberine with cyclosporine, as berberine may slow the breakdown of this medication, increasing its potential side effects.
  • Be cautious when using berberine with dextromethorphan, losartan, and various medications metabolized by the liver, as berberine may alter how quickly these drugs are processed by the liver, potentially changing their effects and side effects.
  • For those on diabetes medications, berberine may lower blood sugar levels. Therefore, it's important to monitor blood sugar closely, as the combination may lead to low blood sugar (hypoglycemia).
  • Berberine can also lower blood pressure, so using it alongside blood pressure drugs might result in severe low blood pressure.
  • If you're taking medications that slow blood clotting, be aware that berberine might increase the risk of bruising and bleeding.
  • Berberine may increase the levels of metformin in the body, particularly when taken two hours before metformin, increasing its effects or side effects.
  • Berberine may interact with herbs and supplements, particularly those that lower blood pressure or blood sugar, slow blood clotting, or have sedative properties. Examples include CBD, garlic, ginger, ginkgo, and L-arginine.
  • Probiotics may be less effective when taken with berberine.
  • There are no known interactions with foods. Berberine is typically used in doses of 0.4-1.5 grams daily, but it’s recommended to consult a healthcare provider for advice on the appropriate dosage for your specific condition.

Side Effects

Taking berberine may lead to side effects. Common berberine side effects may include gastrointestinal issues such as constipation, diarrhea, gas, and stomach cramps. Some individuals might also experience headaches, dizziness, and fatigue.

In rare cases, berberine may lead to more severe side effects that could warrant immediate medical attention. These serious adverse effects may include liver problems and allergic reactions, with symptoms like difficulty breathing, chest pain, hives, swelling, and itching. If any severe side effects develop, seek help from a healthcare provider.


  1. Berberine Herbs and Supplements.MedlinePlus; 2023.

LiverTox: Clinical and Research Information on Drug-Induced Liver Injury [Internet]. Bethesda (MD): National Institute of Diabetes and Digestive and Kidney Diseases; 2012-. Berberine. [Updated 2020 Oct 6].

IMPORTANT NOTE: The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.

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