Known as Atopica (Cyclosporine Modified) in the UK
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ATOPICA (cyclosporine capsules USP) MODIFIED is a new therapy for the control of atopic dermatitis. Unlike other frequently prescribed products, Atopica selectively targets certain specific immune cells responsible for the dogs allergic response. Atopica is an oral form of cyclosporine that immediately forms a microemulsion in an aqueous environment. Cyclosporine, the active ingredient in ATOPICA, is a cyclic polypeptide, immune modulating agent consisting of 11 amino acids. It is produced as a metabolite by the fungal species Beauveria nivea.
ATOPICA should be given at least 2 hours before or after feeding. Insert the capsule directly into the pet's mouth. If a dose is missed, next dose to be administered (without doubling) as soon as possible, but dose no more than once daily.
ATOPICA will initially be given daily until a satisfactory clinical improvement is seen. This will generally be the case within 4 weeks. If no response is obtained within the first 8 weeks, the treatment should be stopped.
WEIGHT (lbs) / DOSAGE (Btwn 1.5 to 3.0mg/lb. daily)
4 - 6.5lbs: 1 x 10mg
6.6 - 9lbs: 2 x 10mg
9.1- 16lbs: 1 x 25mg
16.1 - 33lbs: 1 x 50mg
33.1 - 64lbs: 1 x 100mg
64.1 -79lbs: 1 x 100mg + 1 x 50mg
79.1 - 121bs: 2 x 100mg
Once the clinical signs of atopic dermatitis are satisfactorily controlled, dose adjustment should only be carried out in consultation with Veterinarian.
ATOPICA contains 10mg, 25mg, 50mg or 100mg Cyclosporine A per capsule.
Do not use ATOPICA in dogs less than six months of age or less than 4.4 lbs (2kg) in weight. ATOPICA is not for use in breeding dogs, pregnant or lactating bitches.
The occurrence of adverse reactions is uncommon. Most common are vomiting and diarrhea. Generally are mild and transient and do not require the cessation of the treatment. Divided dosing or administration with a small amount of food may help to resolve. Other side effects are rare and may include lethargy or hyperactivity, anorexia, skin reactions such as lesions or change of hair coat, red and swollen pinnae, muscle weakness or muscle cramps. These effects generally resolve spontaneously after treatment is stopped.
If any serious effects or other effects not mentioned occur, consult Veterinarian.