Astagraf XL (Tacrolimus)

Also Known as Advagraf ER (Tacrolimus)

Prescription medicineOnly Available By Prescription
Sezzle

Top brand choice

Strength Pack Size Qty
Strength
5mg
Pack Size
Qty

You'll have option to make 4 interest-free payments by credit card once your order is confirmed using

What if I find a lower price with another pharmacy?

We guarantee the lowest price on all of our prescription products. If you find your medications cheaper at any other recognized licensed mail order pharmacy, we will not only match their price, we will beat it by 25% of the difference. It is our 125% price match guarantee!

Example: If you find a product on Canada Drugs Direct for $50.00 and find the same product for $40.00 at another mail order pharmacy, we will provide you with a $12.50 discount, bringing your total to $37.50.

To get the discount please make sure to mention the price match to the customer service team when they call to collect payment for your order. Or call toll free at 1-888-904-8467 to place the order through the phone.

Terms & Conditions of Program

  • Guaranteed lowest price is only valid at the time of sale.
  • We will only match the current advertised price.
  • Products must be identical and in stock at the time of placing an order with a licensed mail order pharmacy. They must be an online Canadian pharmacy with an address in Canada.
  • Products must be authentic in brand and size (same manufacturer, same country of manufacture, same pack size, same strength and same quantity).
  • Products must be new. We cannot match the price of any used, short expiry or expired product.
  • Price match can only be issued over the phone with our customer service team. Please note at this time we cannot offer price matching for the products Ozempic or Saxenda.
What is a Generic Drug?

A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.

The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.

Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.

Description

Astagraf XL (tacrolimus extended-release capsules) is a prescription medication that is administered with other medications for preventing organ rejection in patients who have had a kidney transplant.

Astagraf XL comes in 0.5 mg, 1 mg, and 5 mg capsules for oral administration.

Directions

Astagraf XL should be taken as your doctor has instructed.

Your doctor will determine an appropriate dose for you based on other treatments you are receiving and how much you weigh.

The capsules should be taken whole and at the same time each morning; take on an empty stomach. Avoid consuming alcohol, grapefruit, or grapefruit juice.

Astagraf XL should be kept at 25°C (77°F).

Carefully read the medication guide that comes with your prescription for additional instructions for use.

Do not hesitate to reach out to your doctor or pharmacist with any questions or concerns regarding your prescription.

Ingredients

Tacrolimus is the active ingredient in Astagraf XL.

Ethylcellulose NF, hypromellose USP, magnesium stearate NF, lactose monohydrate NF, gelatin NF, titanium dioxide USP, ferric oxide NF, and sodium lauryl sulfate are the inactive ingredients.

Contraindications

Astagraf XL (tacrolimus) capsules should not be prescribed to patients with an allergy to tacrolimus.

Cautions

  • Astagraf XL is associated with the following FDA Boxed Warning:
    • The risk for serious infections and malignancies that may require hospitalization or result in death is increased with Astagraf XL
    • Death in female liver transplant patients is increased with Astagraf XL therapy; therefore, Astagraf XL is not approved for use in liver transplantation
  • Before treatment with Astagraf XL is started, inform your doctor of the following:
    • All the medications you take, including prescription and nonprescription medications, supplements, and vitamins
    • Your allergies
    • Any existing health concerns
    • Your past medical history
    • If you are pregnant
    • If you are breastfeeding
  • Astagraf XL contains the following warnings and precautions:
    • Astagraf XL cannot be substituted for other tacrolimus medications
    • Development of diabetes
    • Kidney issues
    • Neurological issues
    • Elevated blood potassium levels
    • High blood pressure
    • A type of heart arrhythmia called QT interval prolongation
    • Live vaccines should not be administered
    • Pure red cell aplasia
    • Thrombotic microangiopathy (hemolytic uremic syndrome and thrombotic thrombocytopenic purpura)

Side Effects

Astagraf XL side effects include but are not limited to nausea, diarrhea, constipation, swelling, anemia, and tremor. Inform your doctor right away of any side effects that become bothersome or persistent.

Searching for a competitive Astagraf XL cost? Here, you can buy Astagraf XL.

Reference

Astagraf XL. Northbrook, IL: Astellas Pharma US, Inc.; 2023.




IMPORTANT NOTE: The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.

product-reviews Product Reviews