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Anusol Plus Hemorrhoidal Ointment with Anesthetic


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Strength Pack Size Qty
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Example: If you find a product on Canada Drugs Direct for $50.00 and find the same product for $40.00 at another mail order pharmacy, we will provide you with a $12.50 discount, bringing your total to $37.50.

To get the discount please make sure to mention the price match to the customer service team when they call to collect payment for your order. Or call toll free at 1-888-904-8467 to place the order through the phone.

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  • Guaranteed lowest price is only valid at the time of sale.
  • We will only match the current advertised price.
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What is a Generic Drug?

A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.

The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.

Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.


Anusol Plus (zinc sulfate and pramoxine hydrochloride) is a topical ointment used to provide relief from the discomfort and other symptoms associated with internal hemorrhoids. Anusol Plus hemorrhoidal ointment treatment combines the astringent properties of zinc sulfate with the anesthetic effects of pramoxine hydrochloride. This ointment can be particularly helpful for those seeking a hemorrhoidal treatment with an anesthetic.

Fact Table


C21H30O5 (Hydrocortisone) and ZnSO4 (Zinc Sulfate)


US DailyMed


NNo data available for topical bioavailability. Systemic absorption is low

Legal status


Chemical Name

IHydrocortisone / Zinc Sulfate

Elimination half-life

No data for topical use. Oral hydrocortisone has a plasma half-life of 1.5-2 hours

Dosage (Strength)



Category C - Use with caution if benefits outweigh risks


Anusol HC Ointment

Protein binding

90% bound to plasma proteins (hydrocortisone)

PubChem CID

5754 (Hydrocortisone) and 61012024 (Zinc Sulfate)




168410 (Hydrocortisone) and 95769 (Zinc Sulfate)

ATC code

D07AA02 - Hydrocortisone, combinations


DB00635 (Hydrocortisone)


D00093 (Hydrocortisone)

Routes of administration



Anusol Plus is applied as an ointment directly to the affected area. Clean the area with mild soap and water, patting dry before application. Apply the ointment externally to the affected area up to 5 times daily, especially at night, in the morning, and after each bowel movement. For optimal results and comfort, apply the ointment using a fingertip or a cotton swab, making sure to cover the entire affected region. Avoid using excessive pressure during application to prevent further irritation.


Anusol Plus hemorrhoidal ointment with anesthetic contains the active ingredients zinc sulfate and pramoxine hydrochloride.


Do not use Anusol Plus if you are allergic to zinc sulfate, pramoxine hydrochloride, or any other ingredient in Anusol Plus.


  • Before using Anusol Plus, tell your doctor about:
    • Your allergies
    • Any health conditions
    • All the medications and treatments you are currently taking
    • If you are pregnant, planning to become pregnant, or nursing
  • Wash hands before and after applying the ointment.
  • For external use only; avoid ingestion or contact with eyes. Rinse the eyes immediately with water if contact occurs.
  • Stop using and consult your healthcare provider if symptoms persist or worsen after a week.
  • Keep the product stored at room temperature, away from children and pets.

Side Effects

Some possible side effects of Anusol Plus include minor skin irritation, redness, or a temporary burning sensation at the application site. Serious side effects are rare but may include allergic reactions. If you notice any symptoms that persist or worsen, contact your healthcare provider immediately.

Consult your healthcare provider for other potential side effects, warnings, and precautions before starting treatment.


Anusol Plus Product Label. Ewing, NJ: Church & Dwight; 2023.

IMPORTANT NOTE: The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.

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