Ampyra (dalfampridine er)

Also Known as Fampyra

Prescription medicineOnly Available By Prescription

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What if I find a lower price with another pharmacy?

We guarantee the lowest price on all of our prescription products. If you find your medications cheaper at any other recognized licensed mail order pharmacy, we will not only match their price, we will beat it by 25% of the difference. It is our 125% price match guarantee!

Example: If you find a product on Canada Drugs Direct for $50.00 and find the same product for $40.00 at another mail order pharmacy, we will provide you with a $12.50 discount, bringing your total to $37.50.

To get the discount please make sure to mention the price match to the customer service team when they call to collect payment for your order. Or call toll free at 1-888-904-8467 to place the order through the phone.

Terms & Conditions of Program

  • Guaranteed lowest price is only valid at the time of sale.
  • We will only match the current advertised price.
  • Products must be identical and in stock at the time of placing an order with a licensed mail order pharmacy. They must be an online Canadian pharmacy with an address in Canada.
  • Products must be authentic in brand and size (same manufacturer, same country of manufacture, same pack size, same strength and same quantity).
  • Products must be new. We cannot match the price of any used, short expiry or expired product.
  • Price match can only be issued over the phone with our customer service team. Please note at this time we cannot offer price matching for the products Ozempic or Saxenda.
What is a Generic Drug?

A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.

The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.

Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.


Amprya is a medication prescribed to improve walking in adult patients with Multiple Sclerosis (MS). MS is a disease that affects many different parts of the body. It is a condition where the immune system attacks cells of the nervous system and causes permanent damage. Ampyra and other medications can improve symptoms and functioning in patients with MS but cannot cure it.

MS affects multiple systems in the body and can present with various symptoms, including pain, trouble with coordination, trouble thinking, fatigue, weakness, bladder issues, and other symptoms. 

Ampyra is a potassium channel blocker that increases the conduction in nerve cells that have experienced damage from attacks by the immune system.

Fact Table







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Chemical Name


Elimination half-life

125 +/- 23 min

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The usual dose of Ampyra is 10 mg by mouth twice daily (every 12 hours). Do not take more than 20 mg per day unless directed by your healthcare provider.

Do not crush, chew, or open the capsules. Take them whole with or without food.


The active ingredient in Ampyra is dalfampridine


Ampyra has drug-drug interactions with the following medications:

  • Cimetidine
  • Doxepin
  • Dolutegravir
  • Metformin
  • Pantoprazole
  • Quinidine
  • Trilaciclib
  • Trospium


Use caution if you have ever had a seizure or have a seizure disorder. Ampyra -- especially in doses higher than prescribed -- can induce seizures. If you experience one while taking this medication, your doctor should stop it.

Tell your doctor if you have a history of kidney issues.

Do not take 4-aminopyridine (4-AP, fampridine) while taking Ampyra because they have the same active ingredient.

Side Effects

The most common Ampyra side effects may include:

  • Acute exacerbations of multiple sclerosis
  • Anaphylaxis
  • Angioedema
  • Asthenia
  • Back pain
  • Balance impairment
  • Confusion
  • Constipation
  • Dizziness
  • Dyspepsia
  • Headache
  • Insomnia
  • Nasopharyngitis
  • Nausea
  • Paresthesia
  • Pharyngolarygeal pain
  • Seizure
  • Urinary tract infection
  • Vertigo
  • Vomiting


Ampyra [package insert]. Ardsley, NY: Acorda; 2021.

IMPORTANT NOTE: The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.

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