Aklief Cream (Trifarotene)

Prescription medicineOnly Available By Prescription

Top brand choice

Strength Pack Size Qty
0.005 %
Pack Size

You'll have option to make 4 interest-free payments by credit card once your order is confirmed using

What if I find a lower price with another pharmacy?

We guarantee the lowest price on all of our prescription products. If you find your medications cheaper at any other recognized licensed mail order pharmacy, we will not only match their price, we will beat it by 25% of the difference. It is our 125% price match guarantee!

Example: If you find a product on Canada Drugs Direct for $50.00 and find the same product for $40.00 at another mail order pharmacy, we will provide you with a $12.50 discount, bringing your total to $37.50.

To get the discount please make sure to mention the price match to the customer service team when they call to collect payment for your order. Or call toll free at 1-888-904-8467 to place the order through the phone.

Terms & Conditions of Program

  • Guaranteed lowest price is only valid at the time of sale.
  • We will only match the current advertised price.
  • Products must be identical and in stock at the time of placing an order with a licensed mail order pharmacy. They must be an online Canadian pharmacy with an address in Canada.
  • Products must be authentic in brand and size (same manufacturer, same country of manufacture, same pack size, same strength and same quantity).
  • Products must be new. We cannot match the price of any used, short expiry or expired product.
  • Price match can only be issued over the phone with our customer service team. Please note at this time we cannot offer price matching for the products Ozempic or Saxenda.
What is a Generic Drug?

A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.

The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.

Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.


Aklief is a prescription acne medication used for teenagers acne treatment and able to be effective for both acne vulgaris and inflammatory acne. This acne solution is equally effective for the face, shoulders, chest, or back based on where the young person has acne resulting from overactive sebaceous glands that become this way as a young person passes through early puberty. Trifarotene is a retinoid molecule that helps skin with faster replacement of old skin cells while also exfoliating away old cells and limiting new acne blemishes forming.


For topical use on skin only. Keep cream away from eyes, lips, paranasal creases, or mucous membranes.

Apply a thin layer Aklief cream to affected areas once daily on clean, dry skin.

It is best to apply cream in the evening before bed.

Volume of cream applied will vary with body part being treated. Read instruction in pamphlet for more on what standard application guidelines apply for treatment area of body.

Using a moisturizer is recommended while using Aklief cream.


The active ingredient in Aklief cream is Trifarotene.


For use with ages 9 and up only.

Skin with cuts or abrasions, eczematous, or sunburnt skin should not be treated with this acne reduction cream.

Exposure to sunlight and sunlamps should be limited. Use sunscreen and protective clothing to cover treated skin in instances where skin will have direct, strong sunlight exposure.

Using a wax or use any type of depilatory hair removal product on skin while treating with Aklief cream is inadvisable.


No established drug interactions risks associated with using Aklief for acne treatment have been established, but it is still wise to discuss any other facial skincare products you may be using with the pharmacist before you buy Aklief acne cream.

Side Effects

Possible side effects from using Aklief cream include localized skin irritation with redness, scaling, dryness, or stinging / burning. If side effects are seen it may be best to discontinue use and speak to your doctor about acne treatment for teens options.

IMPORTANT NOTE: The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.

product-reviews Product Reviews